product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Thioredoxin 1 (C63C6) Rabbit mAb
catalog :
2429
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C63C6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig s5
Trzeciecka A, Klossowski S, Bajor M, Zagozdzon R, Gaj P, Muchowicz A, et al. Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma. Oncotarget. 2016;7:1717-31 pubmed publisher
  • western blot; human; 1:1000
Morrison J, Pike L, Sams S, Sharma V, Zhou Q, Severson J, et al. Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor in thyroid cancer. Mol Cancer. 2014;13:62 pubmed publisher
Zheng Z, Fan S, Zheng J, Huang W, Gasparetto C, Chao N, et al. Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma. J Hematol Oncol. 2018;11:29 pubmed publisher
Shen W, Yau B, Lee S, Zhu L, Yam M, Gillies M. Effects of Ranibizumab and Aflibercept on Human Müller Cells and Photoreceptors under Stress Conditions. Int J Mol Sci. 2017;18: pubmed publisher
Gao K, Chi Y, Sun W, Takeda M, Yao J. 5'-AMP-activated protein kinase attenuates adriamycin-induced oxidative podocyte injury through thioredoxin-mediated suppression of the apoptosis signal-regulating kinase 1-P38 signaling pathway. Mol Pharmacol. 2014;85:460-71 pubmed publisher
Prickett T, Zerlanko B, Gartner J, Parker S, Dutton Regester K, Lin J, et al. Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin. J Invest Dermatol. 2014;134:452-460 pubmed publisher
Xiao F, Li Y, Dai L, Deng Y, Zou Y, Li P, et al. Hexavalent chromium targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent caspase-3 activation in L-02 hepatocytes. Int J Mol Med. 2012;30:629-35 pubmed publisher
Vrba J, Orolinova E, Ulrichova J. Induction of heme oxygenase-1 by Macleaya cordata extract and its constituent sanguinarine in RAW264.7 cells. Fitoterapia. 2012;83:329-35 pubmed publisher
Randazzo J, Zhang Z, Hoff M, Kawada H, Sachs A, Yuan Y, et al. Orally active multi-functional antioxidants are neuroprotective in a rat model of light-induced retinal damage. PLoS ONE. 2011;6:e21926 pubmed publisher
Yu Y, Richardson D. Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1. J Biol Chem. 2011;286:15413-27 pubmed publisher
product information
SKU :
2429S
Product-Name :
Thioredoxin 1 (C63C6) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
12
Host :
Rabbit
Target :
Thioredoxin 1
Primary-Protein :
TXN
Alt-Names :
ADF,ATL-derived factor,DKFZp686B1993,MGC61975,SASP,Surface-associated sulphydryl protein,THIO,TRDX,TRX,TRX1,TXN,Thioredoxin
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.