p14 ARF (4C6/4) Mouse mAb | Cell Signaling Technology 2407 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

p14 ARF (4C6/4) Mouse mAb

catalog :

2407

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4C6/4

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, proximity ligation assay

more info or order :

Cell Signaling Technology product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 6d	Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee S, Keerthikumar S, et al. Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis. Nat Commun. 2021;12:3950 pubmed publisher
western blot; human; 1:1000; loading ...; fig s2d	Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, et al. Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition. Nat Commun. 2019;10:1665 pubmed publisher
immunohistochemistry; human; 1:50; loading ...; fig 2h	Xie Y, Fan H, Lu W, Yang Q, Nurkesh A, Yeleussizov T, et al. Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer. Oncogene. 2019;38:2967-2983 pubmed publisher
western blot; human; loading ...; fig 2c	Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher
western blot; human; fig S1B	Ding X, Jiang W, Zhou P, Liu L, Wan X, Yuan X, et al. Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7). PLoS ONE. 2015;10:e0145023 pubmed publisher
proximity ligation assay; human; 1:100; fig 7c	Wang L, Liu R, Ye P, Wong C, Chen G, Zhou P, et al. Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation. Nat Commun. 2015;6:5909 pubmed publisher
	Xie Y, Lu W, Liu S, Yang Q, Goodwin J, Sathyanarayana S, et al. MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo. Oncotarget. 2016;7:47609-47619 pubmed publisher
	Hesse R, Kouklis G, Ahituv N, Pomerantz J. The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration. elife. 2015;4: pubmed publisher
	Kong L, Hao Q, Wang Y, Zhou P, Zou B, Zhang Y. Regulation of p53 expression and apoptosis by vault RNA2-1-5p in cervical cancer cells. Oncotarget. 2015;6:28371-88 pubmed publisher
	Lo D, Zhang Y, Dai M, Sun X, Zeng S, Lu H. Nucleostemin stabilizes ARF by inhibiting the ubiquitin ligase ULF. Oncogene. 2015;34:1688-97 pubmed publisher
	Lu W, Xie Y, Ma Y, Matusik R, Chen Z. ARF represses androgen receptor transactivation in prostate cancer. Mol Endocrinol. 2013;27:635-48 pubmed publisher
	To K, Pajovic S, Gallie B, Thériault B. Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development. BMC Cancer. 2012;12:69 pubmed publisher
	Shao C, Folkard M, Held K, Prise K. Estrogen enhanced cell-cell signalling in breast cancer cells exposed to targeted irradiation. BMC Cancer. 2008;8:184 pubmed publisher

product information

SKU :

2407S

Product-Name :

p14 ARF (4C6/4) Mouse mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

Applications :

Immunohistochemistry (Paraffin)

Product-Category :

Cell Cycle / Checkpoint Control

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Mouse

Target :

p14 Arf

Primary-Protein :

p14ARF

Alt-Names :

ARF,CD2A2,CDK4 inhibitor p16-INK4,CDK4I,CDKN2,CDKN2A,CMM2,Cyclin-dependent kinase inhibitor 2A, isoform 4,INK4,INK4a,MLM,MTS-1,MTS1,TP16,cell cycle negative regulator beta,cyclin-dependent kinase 4 inhibitor A,cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4),cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3,cyclin-dependent kinase inhibitor p16,multiple tumor suppressor 1,p14,p14ARF,p16,p16-INK4,p16-INK4a,p16INK4,p16INK4a,p19,p19ARF

more info or order :

Cell Signaling Technology product webpage