product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-IRS-1 (Ser307) Antibody
catalog :
2381S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 5
Published Application/Species/DilutionReference
  • western blot; mouse; 1:500; fig 3
Barone E, Di Domenico F, Cassano T, Arena A, Tramutola A, Lavecchia M, et al. Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm. Free Radic Biol Med. 2016;91:127-42 pubmed publisher
  • western blot; mouse; 1:1500
Vinue A, Andrés-Blasco I, Herrero-Cervera A, Piqueras L, Andres V, Burks D, et al. Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling. Biochim Biophys Acta. 2015;1852:1729-42 pubmed publisher
  • western blot; rat; 1:1000
Kang E, Cho J. Effects of treadmill exercise on brain insulin signaling and β-amyloid in intracerebroventricular streptozotocin induced-memory impairment in rats. J Exerc Nutrition Biochem. 2014;18:89-96 pubmed publisher
Hoeks J, Wilde J, Hulshof M, Berg S, Schaart G, Dijk K, et al. High fat diet-induced changes in mouse muscle mitochondrial phospholipids do not impair mitochondrial respiration despite insulin resistance. PLoS ONE. 2011;6:e27274 pubmed publisher
Wen H, Gris D, Lei Y, JHA S, Zhang L, Huang M, et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol. 2011;12:408-15 pubmed publisher
product information
SKU :
2381S
Product-Name :
Phospho-IRS-1 (Ser307) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
180
Host :
Rabbit
Target :
IRS-1 (Ser307) phosphate
Primary-Protein :
IRS1
Alt-Names :
HIRS-1,IRS-1,IRS1,Insulin receptor substrate 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.