product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
IKKβ (2C8) Rabbit mAb
catalog :
2370S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
clone name :
2C8
reactivity :
human, mouse, rat
application :
western blot
citations: 6
Published Application/Species/DilutionReference
  • western blot (knockout validation); mouse; 1 ug/ml; fig 1
Zhao T, Yang L, Sun Q, Arguello M, Ballard D, Hiscott J, et al. The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways. Nat Immunol. 2007;8:592-600 pubmed
  • western blot; human; fig 1
Strohecker A, Joshi S, Possemato R, Abraham R, Sabatini D, White E. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. Oncogene. 2015;34:5662-76 pubmed publisher
Luedde T, Heinrichsdorff J, De Lorenzi R, De Vos R, Roskams T, Pasparakis M. IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver. Proc Natl Acad Sci U S A. 2008;105:9733-8 pubmed publisher
Barisic S, Schmidt C, Walczak H, Kulms D. Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFkappaB activation via Src-dependent blockade of PP2A. Biochem Pharmacol. 2010;80:439-47 pubmed publisher
Sarkar S, Han J, Sinsimer K, Liao B, Foster R, Brewer G, et al. RNA-binding protein AUF1 regulates lipopolysaccharide-induced IL10 expression by activating IkappaB kinase complex in monocytes. Mol Cell Biol. 2011;31:602-15 pubmed publisher
Gardner A, Fisher A, Richter C, Johnson G, Moisey E, Brodlie M, et al. The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation. Am J Pathol. 2012;180:2293-308 pubmed publisher
product information
SKU :
2370S
Product-Name :
IKKβ (2C8) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
87
Host :
Rabbit
Target :
IKK-beta
Primary-Protein :
IKK-beta
Alt-Names :
FLJ40509,I-kappa-B kinase 2,I-kappa-B-kinase beta,IKBKB,IKK-B,IKK-beta,IKK2,IKKB,Inhibitor of nuclear factor kappa-B kinase subunit beta,MGC131801,NFKBIKB,Nuclear factor NF-kappa-B inhibitor kinase beta,inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.