| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; rat; fig 3a
| Bott L, Salomons F, Maric D, Liu Y, Merry D, Fischbeck K, et al. The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C(Cdh1) ubiquitin ligase complex. Sci Rep. 2016;6:27703 pubmed publisher |
- western blot; human; loading ...; fig 3e
| Titov D, Cracan V, Goodman R, Peng J, Grabarek Z, Mootha V. Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio. Science. 2016;352:231-5 pubmed publisher |
- immunocytochemistry; human; 1:1000; fig 7
- western blot; human; 1:1000; fig 2
| Chavali P, Chandrasekaran G, Barr A, Tátrai P, Taylor C, Papachristou E, et al. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun. 2016;7:11005 pubmed publisher |
- western blot; mouse; fig 3a
| Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, et al. CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene. 2016;35:2893-901 pubmed publisher |
- western blot; human; fig 5a
| Matsuda S, Adachi J, Ihara M, Tanuma N, Shima H, Kakizuka A, et al. Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor. Nucleic Acids Res. 2016;44:636-47 pubmed publisher |
- western blot; human; fig 3
| Martinez N, Agosto L, Qiu J, Mallory M, Gazzara M, Barash Y, et al. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev. 2015;29:2054-66 pubmed publisher |
- immunoprecipitation; human; fig 2d
- western blot; human; fig 2d
| Perera R, Stoykova S, Nicolay B, Ross K, Fitamant J, Boukhali M, et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 2015;524:361-5 pubmed publisher |
| Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher |
| Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina J, et al. ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain. Sci Rep. 2017;7:41290 pubmed publisher |
| Tagal V, Wei S, Zhang W, Brekken R, Posner B, Peyton M, et al. SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers. Nat Commun. 2017;8:14098 pubmed publisher |
| Yang C, Sengupta S, Hegde P, Mitra J, Jiang S, Holey B, et al. Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A. Nucleic Acids Res. 2017;45:739-748 pubmed publisher |
| Vanhoutte D, Schips T, Kwong J, Davis J, Tjondrokoesoemo A, Brody M, et al. Thrombospondin expression in myofibers stabilizes muscle membranes. elife. 2016;5: pubmed publisher |
| Wang Q, Zhang X, Han Y, Wang X, Gao G. M2BP inhibits HIV-1 virion production in a vimentin filaments-dependent manner. Sci Rep. 2016;6:32736 pubmed publisher |
| Neubauer H, Pham D, Zebol J, Moretti P, Peterson A, Leclercq T, et al. An oncogenic role for sphingosine kinase 2. Oncotarget. 2016;7:64886-64899 pubmed publisher |
| Weaver R, Limzerwala J, Naylor R, Jeganathan K, Baker D, van Deursen J. BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer. elife. 2016;5: pubmed publisher |
| Jo Y, Park N, Park S, Kim B, Shin J, Jo D, et al. O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity. Oncotarget. 2016;7:57186-57196 pubmed publisher |
| Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher |
| Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, et al. Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat Commun. 2016;7:12347 pubmed publisher |
| Kweon H, Kim D, Bae Y, Park J, Suh B. Acid-Sensing Ion Channel 2a (ASIC2a) Promotes Surface Trafficking of ASIC2b via Heteromeric Assembly. Sci Rep. 2016;6:30684 pubmed publisher |
| Wang Y, Sun H, Wang J, Wang H, Meng L, Xu C, et al. DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity. Cell Death Dis. 2016;7:e2316 pubmed publisher |
| Nakashima H, Ohkawara B, Ishigaki S, Fukudome T, Ito K, Tsushima M, et al. R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5. Sci Rep. 2016;6:28512 pubmed publisher |
| Liu C, Lin S, Hsu H, Yang S, Lin C, Yang M, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016;7:11798 pubmed publisher |
| Airik R, Schueler M, Airik M, Cho J, Ulanowicz K, Porath J, et al. SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling. PLoS ONE. 2016;11:e0156081 pubmed publisher |
| de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed publisher |
| Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed publisher |
| Dreer M, Fertey J, van de Poel S, Straub E, Madlung J, Macek B, et al. Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication. PLoS Pathog. 2016;12:e1005556 pubmed publisher |
| Sorber R, Teper Y, Abisoye Ogunniyan A, Waterfall J, Davis S, Killian J, et al. Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion. PLoS ONE. 2016;11:e0149833 pubmed publisher |
| Zhao C, Deng Y, Liu L, Yu K, Zhang L, Wang H, et al. Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nat Commun. 2016;7:10883 pubmed publisher |
| Kayama T, Mori M, Ito Y, Matsushima T, Nakamichi R, Suzuki H, et al. Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon. Mol Cell Biol. 2016;36:1297-309 pubmed publisher |
| Boeynaems S, Bogaert E, Michiels E, Gijselinck I, Sieben A, JoviÄić A, et al. Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD. Sci Rep. 2016;6:20877 pubmed publisher |
| Lai S, Pelech S. Regulatory roles of conserved phosphorylation sites in the activation T-loop of the MAP kinase ERK1. Mol Biol Cell. 2016;27:1040-50 pubmed publisher |
| Zhang Y, Cai R, Zhou R, Li Y, Liu L. Tousled-like kinase mediated a new type of cell death pathway in Drosophila. Cell Death Differ. 2016;23:146-57 pubmed publisher |
| Yang B, Zhang M, Gao J, Li J, Fan L, Xiang G, et al. Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer. Oncotarget. 2015;6:37613-25 pubmed publisher |
| Xu D, Shan B, Lee B, Zhu K, Zhang T, Sun H, et al. Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system. elife. 2015;4:e10510 pubmed publisher |
| Young G, Radhakrishnan V, Centuori S, Gomes C, Martinez J. Comparative analysis of 14-3-3 isoform expression and epigenetic alterations in colorectal cancer. BMC Cancer. 2015;15:826 pubmed publisher |
| Xiong Y, Su H, Lv P, Ma Y, Wang S, Miao H, et al. A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region. Oncotarget. 2015;6:35625-35 pubmed publisher |
| Zulliger R, Conley S, Mwoyosvi M, Stuck M, Azadi S, Naash M. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS ONE. 2015;10:e0138508 pubmed publisher |
| Fekrmandi F, Wang T, White J. The hormone-bound vitamin D receptor enhances the FBW7-dependent turnover of NF-κB subunits. Sci Rep. 2015;5:13002 pubmed publisher |
| Yarosh C, Tapescu I, Thompson M, Qiu J, Mallory M, Fu X, et al. TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acids Res. 2015;43:9006-16 pubmed publisher |
| Qin Y, Guo T, Li G, Tang T, Zhao S, Jiao X, et al. CSB-PGBD3 Mutations Cause Premature Ovarian Failure. PLoS Genet. 2015;11:e1005419 pubmed publisher |
| Bertoli G, Cava C, Castiglioni I. MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer. Theranostics. 2015;5:1122-43 pubmed publisher |
| Golden E, Benito Gonzalez A, Doetzlhofer A. The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015;112:E3864-73 pubmed publisher |
| Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed |
| Cluxton C, Caffrey B, Kinsella G, Moynagh P, Fares M, Fallon P. Functional conservation of an ancestral Pellino protein in helminth species. Sci Rep. 2015;5:11687 pubmed publisher |
| Tang X, Chen X, Xu Y, Qiao Y, Zhang X, Wang Y, et al. CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells. Cell Signal. 2015;27:1694-702 pubmed publisher |
| Simões A, Pereira D, Gomes S, Brito H, Carvalho T, French A, et al. Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation. Cell Death Dis. 2015;6:e1718 pubmed publisher |
| Ikeda M, Ide T, Fujino T, Arai S, Saku K, Kakino T, et al. Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress. PLoS ONE. 2015;10:e0119687 pubmed publisher |
| Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed publisher |
| Popa A, Zhang W, Harrison M, Goodner K, Kazakov T, Goodwin E, et al. Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection. PLoS Pathog. 2015;11:e1004699 pubmed publisher |
| Mo X, Yang C, Wang X, Burkhardt B, Li Y, Xia H, et al. F3MB(PANDER) decreases mice hepatic triglyceride and is associated with decreased DGAT1 expression. PLoS ONE. 2015;10:e0117156 pubmed publisher |
| Hornbeck P, Zhang B, Murray B, Kornhauser J, Latham V, Skrzypek E. PhosphoSitePlus, 2014: mutations, PTMs and recalibrations. Nucleic Acids Res. 2015;43:D512-20 pubmed publisher |
| Lin L, Pan S, Zhao J, Liu C, Wang P, Fu L, et al. HSPD1 interacts with IRF3 to facilitate interferon-beta induction. PLoS ONE. 2014;9:e114874 pubmed publisher |
| Kim J, Shim M. Prostaglandin F2α receptor (FP) signaling regulates Bmp signaling and promotes chondrocyte differentiation. Biochim Biophys Acta. 2015;1853:500-12 pubmed publisher |
| Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, et al. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nat Commun. 2014;5:5482 pubmed publisher |
| Zhou L, Yeo A, Ballarano C, Weber U, Allen K, Gilmore T, et al. Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO). Biochemistry. 2014;53:7929-44 pubmed publisher |
| Duarte L, Young A, Wang Z, Wu H, Panda T, Kou Y, et al. Histone H3.3 and its proteolytically processed form drive a cellular senescence programme. Nat Commun. 2014;5:5210 pubmed publisher |
| Ortiz Ruiz M, Ãlvarez Fernández S, Parrott T, Zaknoen S, Burrows F, Ocaña A, et al. Therapeutic potential of ERK5 targeting in triple negative breast cancer. Oncotarget. 2014;5:11308-18 pubmed |
| Lee S, Seo A, Park B, Jo H, Huh Y. Neuropathic pain model of peripheral neuropathies mediated by mutations of glycyl-tRNA synthetase. J Korean Med Sci. 2014;29:1138-44 pubmed publisher |
| Witek M, Snook A, Lin J, Blomain E, Xiang B, Magee M, et al. A novel CDX2 isoform regulates alternative splicing. PLoS ONE. 2014;9:e104293 pubmed publisher |
| Izumi H, Kaneko Y. Trim32 facilitates degradation of MYCN on spindle poles and induces asymmetric cell division in human neuroblastoma cells. Cancer Res. 2014;74:5620-30 pubmed publisher |
| Huang Y, Bulavin D. Oncogene-mediated regulation of p53 ISGylation and functions. Oncotarget. 2014;5:5808-18 pubmed |
| Lin T, Chou C, Chung H, Chiang C, Li C, Wu J, et al. Hypoxia-inducible factor 2 alpha is essential for hepatic outgrowth and functions via the regulation of leg1 transcription in the zebrafish embryo. PLoS ONE. 2014;9:e101980 pubmed publisher |
| Failler M, Gee H, Krug P, Joo K, Halbritter J, Belkacem L, et al. Mutations of CEP83 cause infantile nephronophthisis and intellectual disability. Am J Hum Genet. 2014;94:905-14 pubmed publisher |
| Cross S, Macalinao D, McKie L, Rose L, Kearney A, Rainger J, et al. A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LDB1-mediated dimerization [corrected]. PLoS Genet. 2014;10:e1004359 pubmed publisher |
| Michel M, Wilhelmi I, Schultz A, Preussner M, Heyd F. Activation-induced tumor necrosis factor receptor-associated factor 3 (Traf3) alternative splicing controls the noncanonical nuclear factor ?B pathway and chemokine expression in human T cells. J Biol Chem. 2014;289:13651-60 pubmed publisher |
| Zhang X, Ling J, Barcia G, Jing L, Wu J, Barry B, et al. Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. Am J Hum Genet. 2014;94:547-58 pubmed publisher |
| Cimica V, Dalrymple N, Roth E, Nasonov A, Mackow E. An innate immunity-regulating virulence determinant is uniquely encoded by the Andes virus nucleocapsid protein. MBio. 2014;5: pubmed publisher |
| Kim S, Rhee K. Importance of the CEP215-pericentrin interaction for centrosome maturation during mitosis. PLoS ONE. 2014;9:e87016 pubmed publisher |
| Wolff N, Ghio A, Garrick L, Garrick M, Zhao L, Fenton R, et al. Evidence for mitochondrial localization of divalent metal transporter 1 (DMT1). FASEB J. 2014;28:2134-45 pubmed publisher |
| Motta Mena L, Reade A, Mallory M, Glantz S, Weiner O, Lynch K, et al. An optogenetic gene expression system with rapid activation and deactivation kinetics. Nat Chem Biol. 2014;10:196-202 pubmed publisher |
| Wang W, Razy Krajka F, Siu E, Ketcham A, Christiaen L. NK4 antagonizes Tbx1/10 to promote cardiac versus pharyngeal muscle fate in the ascidian second heart field. PLoS Biol. 2013;11:e1001725 pubmed publisher |
| Lamb T, Vickery J, Bell Pedersen D. Regulation of gene expression in Neurospora crassa with a copper responsive promoter. G3 (Bethesda). 2013;3:2273-80 pubmed publisher |
| Thompson R, Vardinogiannis I, Gilmore T. Identification of an NF-?B p50/p65-responsive site in the human MIR155HG promoter. BMC Mol Biol. 2013;14:24 pubmed publisher |
| Bujalka H, Koenning M, Jackson S, Perreau V, Pope B, Hay C, et al. MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. PLoS Biol. 2013;11:e1001625 pubmed publisher |
| Ren G, Beech C, Smas C. The immunoglobulin superfamily protein differentiation of embryonic stem cells 1 (dies1) has a regulatory role in preadipocyte to adipocyte conversion. PLoS ONE. 2013;8:e65531 pubmed publisher |
| Chaudhuri D, Sancak Y, Mootha V, Clapham D. MCU encodes the pore conducting mitochondrial calcium currents. elife. 2013;2:e00704 pubmed publisher |
| Thompson J, Shuttleworth T. How many Orai's does it take to make a CRAC channel?. Sci Rep. 2013;3:1961 pubmed publisher |
| Reis A, McCauley J. The influenza virus protein PB1-F2 interacts with IKK? and modulates NF-?B signalling. PLoS ONE. 2013;8:e63852 pubmed publisher |
| Cao K, Lailler N, Zhang Y, Kumar A, Uppal K, Liu Z, et al. High-resolution mapping of h1 linker histone variants in embryonic stem cells. PLoS Genet. 2013;9:e1003417 pubmed publisher |
| Hlawatsch J, Karlstetter M, Aslanidis A, Lückoff A, Walczak Y, Plank M, et al. Sterile alpha motif containing 7 (samd7) is a novel crx-regulated transcriptional repressor in the retina. PLoS ONE. 2013;8:e60633 pubmed publisher |
| El Zaatari M, Kao J, Tessier A, Bai L, Hayes M, Fontaine C, et al. Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS ONE. 2013;8:e58935 pubmed publisher |
| Shpargel K, Sengoku T, Yokoyama S, Magnuson T. UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet. 2012;8:e1002964 pubmed publisher |
| Lamers F, Schild L, Koster J, Speleman F, Øra I, Westerhout E, et al. Identification of BIRC6 as a novel intervention target for neuroblastoma therapy. BMC Cancer. 2012;12:285 pubmed publisher |
| Schmidt P, Sparrow L, Attwood R, Xiao X, Adams T, McKimm Breschkin J. Taking down the FLAG! How insect cell expression challenges an established tag-system. PLoS ONE. 2012;7:e37779 pubmed publisher |
| Choi Y, Sandford G, Nicholas J. Human herpesvirus 8 interferon regulatory factor-mediated BH3-only protein inhibition via Bid BH3-B mimicry. PLoS Pathog. 2012;8:e1002748 pubmed publisher |
| Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho Santos M, et al. Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal. PLoS Genet. 2012;8:e1002576 pubmed publisher |
| Chuang C, Yang D, Bai G, Freeland A, Pruitt S, Schimenti J. Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells. Nucleic Acids Res. 2012;40:4914-24 pubmed publisher |
| Hornbeck P, Kornhauser J, Tkachev S, Zhang B, Skrzypek E, Murray B, et al. PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse. Nucleic Acids Res. 2012;40:D261-70 pubmed publisher |
| Lamb T, Goldsmith C, Bennett L, Finch K, Bell Pedersen D. Direct transcriptional control of a p38 MAPK pathway by the circadian clock in Neurospora crassa. PLoS ONE. 2011;6:e27149 pubmed publisher |
| Janas M, Khaled M, Schubert S, Bernstein J, Golan D, Veguilla R, et al. Feed-forward microprocessing and splicing activities at a microRNA-containing intron. PLoS Genet. 2011;7:e1002330 pubmed publisher |
| Halder U, Bagchi P, Chattopadhyay S, Dutta D, Chawla Sarkar M. Cell death regulation during influenza A virus infection by matrix (M1) protein: a model of viral control over the cellular survival pathway. Cell Death Dis. 2011;2:e197 pubmed publisher |
| Zhao J, Yue W, Zhu M, Du M. AMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5. J Biol Chem. 2011;286:16426-34 pubmed publisher |
| Forrester M, Eyler C, Rich J. Bacterial flavohemoglobin: a molecular tool to probe mammalian nitric oxide biology. Biotechniques. 2011;50:41-5 pubmed publisher |
| Khan M, Vaidya A, Meucci O. CXCL12-mediated regulation of ANP32A/Lanp, a component of the inhibitor of histone acetyl transferase (INHAT) complex, in cortical neurons. J Neuroimmune Pharmacol. 2011;6:163-70 pubmed publisher |
| Pfeffer L, Brisson B, Lei H, Barton E. The insulin-like growth factor (IGF)-I E-peptides modulate cell entry of the mature IGF-I protein. Mol Biol Cell. 2009;20:3810-7 pubmed publisher |
