product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Chk1 (Ser317) Antibody
catalog :
2344
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, rat
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig s10a, s10b
Nam J, Kim A, Choi S, Kim J, Choi K, Cho S, et al. An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage. Nat Commun. 2021;12:3279 pubmed publisher
  • western blot; human; loading ...; fig 3b
Moses N, Zhang M, Wu J, Hu C, Xiang S, Geng X, et al. HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1. Cells. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 3a
Liu Z, Yanagisawa K, Griesing S, Iwai M, Kano K, Hotta N, et al. TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas. Oncogene. 2017;36:3740-3748 pubmed publisher
  • western blot; human; loading ...; fig 1d
Nagano T, Nakano M, Nakashima A, Onishi K, Yamao S, Enari M, et al. Identification of cellular senescence-specific genes by comparative transcriptomics. Sci Rep. 2016;6:31758 pubmed publisher
  • western blot; human; fig 4
Morales J, Richard P, Patidar P, Motea E, Dang T, Manley J, et al. XRN2 Links Transcription Termination to DNA Damage and Replication Stress. PLoS Genet. 2016;12:e1006107 pubmed publisher
  • western blot; human; fig 7h
Choe K, Nicolae C, Constantin D, Imamura Kawasawa Y, Delgado Diaz M, De S, et al. HUWE1 interacts with PCNA to alleviate replication stress. EMBO Rep. 2016;17:874-86 pubmed publisher
  • western blot; human; fig 5
Huang C, Cheng J, Bawa Khalfe T, Yao X, Chin Y, Yeh E. SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability. Cell Rep. 2016;15:147-157 pubmed publisher
  • western blot; human; loading ...; fig 1a
Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  • western blot; human; 1:500; fig s6c
Walter D, Hoffmann S, Komseli E, Rappsilber J, Gorgoulis V, Sørensen C. SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication. Nat Commun. 2016;7:10530 pubmed publisher
  • western blot; human; fig 1
Moudry P, Watanabe K, Wolanin K, Bartkova J, Wassing I, Watanabe S, et al. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. J Cell Biol. 2016;212:281-8 pubmed publisher
  • western blot; human; fig 2d
Baude A, Aaes T, Zhai B, Al Nakouzi N, Oo H, Daugaard M, et al. Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination. Nucleic Acids Res. 2016;44:2214-26 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5d
Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed publisher
  • western blot; human; 1:1000; fig 5
Hassan M, El Khattouti A, Ejaeidi A, Ma T, Day W, Espinoza I, et al. Elevated Expression of Hepatoma Up-Regulated Protein Inhibits γ-Irradiation-Induced Apoptosis of Prostate Cancer Cells. J Cell Biochem. 2016;117:1308-18 pubmed publisher
  • western blot; human; 1:1000; fig 2
Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
  • western blot; human
Mortusewicz O, Evers B, Helleday T. PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites. Oncogene. 2016;35:761-70 pubmed publisher
product information
SKU :
2344S
Product-Name :
Phospho-Chk1 (Ser317) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, R, Mk, Mi
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
56
Host :
Rabbit
Target :
Chk1 (Ser317) phosphate
Primary-Protein :
Chk1
Alt-Names :
CHEK1,CHK1,CHK1 checkpoint homolog (S. pombe),Checkpoint, S. pombe, homolog of, 1,Serine/threonine-protein kinase Chk1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.