| Published Application/Species/Dilution | Reference |
|---|
- western blot; human; 1:500; fig 4
| Harley M, Murina O, Leitch A, Higgs M, Bicknell L, Yigit G, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nat Genet. 2016;48:36-43 pubmed publisher |
- western blot; human; fig s2
| Tepper S, Jeschke J, Böttcher K, Schmidt A, Davari K, Muller P, et al. PARP activation promotes nuclear AID accumulation in lymphoma cells. Oncotarget. 2016;7:13197-208 pubmed publisher |
- western blot; mouse; 1:1000; fig s1
| Yang C, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, et al. Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells. Nat Commun. 2016;7:12135 pubmed publisher |
- immunocytochemistry; human
- western blot; human
| Mortusewicz O, Evers B, Helleday T. PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites. Oncogene. 2016;35:761-70 pubmed publisher |
- western blot; common platanna; fig S3
| Aparicio T, Baer R, Gottesman M, Gautier J. MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts. J Cell Biol. 2016;212:399-408 pubmed publisher |
- western blot; human; 1:1000; fig s4
| Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, et al. New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress. Nucleic Acids Res. 2016;: pubmed |
- western blot; human; fig 5b
| Moniz S, Bandarra D, Biddlestone J, Campbell K, Komander D, Bremm A, et al. Cezanne regulates E2F1-dependent HIF2α expression. J Cell Sci. 2015;128:3082-93 pubmed publisher |
| Sekimoto T, Oda T, Kurashima K, Hanaoka F, Yamashita T. Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication. Mol Cell Biol. 2015;35:699-715 pubmed publisher |
- western blot; human; fig 3
| Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed publisher |
- immunocytochemistry; mouse; 1:50; fig 5c,e
| Fedoriw A, Menon D, Kim Y, Mu W, Magnuson T. Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes. Development. 2015;142:2972-80 pubmed publisher |
- other; mouse; 1:1000; fig s1
| Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher |
- western blot; human; fig 4
| Chung Y, Pan C, Liou W, Sheu M, Lin W, Chen T, et al. NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway. J Pharmacol Sci. 2014;124:7-17 pubmed |
- western blot; human; fig 4
| Moskwa P, Zinn P, Choi Y, Shukla S, Fendler W, Chen C, et al. A functional screen identifies miRs that induce radioresistance in glioblastomas. Mol Cancer Res. 2014;12:1767-78 pubmed publisher |
| Lin B, Gupta D, Heinen C. Human pluripotent stem cells have a novel mismatch repair-dependent damage response. J Biol Chem. 2014;289:24314-24 pubmed publisher |
- western blot; human; 1:1000; fig s3
| Chan Y, West S. Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nat Commun. 2014;5:4844 pubmed publisher |
| Osterman M, Kathawa D, Liu D, Guo H, Zhang C, Li M, et al. Elevated DNA damage response in pancreatic cancer. Histochem Cell Biol. 2014;142:713-20 pubmed publisher |
| Kaistha B, Honstein T, Muller V, Bielak S, Sauer M, Kreider R, et al. Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells. Br J Cancer. 2014;111:1780-7 pubmed publisher |
- western blot; chicken
- western blot; human
| Tuul M, Kitao H, Iimori M, Matsuoka K, Kiyonari S, Saeki H, et al. Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance. PLoS ONE. 2013;8:e55361 pubmed publisher |
| Wei Q, Li J, Liu T, Tong X, Ye X. Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation. J Biol Chem. 2013;288:19715-25 pubmed publisher |
| Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T. SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways. Cell Cycle. 2013;12:3770-80 pubmed publisher |
- immunocytochemistry; mouse
- western blot; mouse
| Luebben S, Kawabata T, Akre M, Lee W, Johnson C, O'Sullivan M, et al. Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res. 2013;41:10283-97 pubmed publisher |
| Blakemore L, Boes C, Cordell R, Manson M. Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage. Carcinogenesis. 2013;34:351-60 pubmed publisher |
- immunocytochemistry; human; fig 4
| Sakasai R, Teraoka H, Takagi M, Tibbetts R. Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison. J Biol Chem. 2010;285:15201-8 pubmed publisher |
| Kubara P, Kernéis-Golsteyn S, Studény A, Lanser B, Meijer L, Golsteyn R. Human cells enter mitosis with damaged DNA after treatment with pharmacological concentrations of genotoxic agents. Biochem J. 2012;446:373-81 pubmed publisher |
| Bartucci M, Svensson S, Romania P, Dattilo R, Patrizii M, Signore M, et al. Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy. Cell Death Differ. 2012;19:768-78 pubmed publisher |
| Kunnev D, Rusiniak M, Kudla A, Freeland A, Cady G, Pruitt S. DNA damage response and tumorigenesis in Mcm2-deficient mice. Oncogene. 2010;29:3630-8 pubmed publisher |
| Nam E, Zhao R, Glick G, Bansbach C, Friedman D, Cortez D. Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase. J Biol Chem. 2011;286:28707-14 pubmed publisher |
