product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-eEF2 (Thr56) Antibody
catalog :
2331
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 4a
Salazar S, Gallardo C, Kaufman A, Herber C, Haas L, Robinson S, et al. Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease. J Neurosci. 2017;37:9207-9221 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1c
Biever A, Boubaker Vitre J, Cutando L, Gracia Rubio I, Costa Mattioli M, Puighermanal E, et al. Repeated Exposure to D-Amphetamine Decreases Global Protein Synthesis and Regulates the Translation of a Subset of mRNAs in the Striatum. Front Mol Neurosci. 2016;9:165 pubmed publisher
  • western blot; mouse; fig 4a
Zanos P, Moaddel R, Morris P, Georgiou P, Fischell J, Elmer G, et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature. 2016;533:481-6 pubmed publisher
  • western blot; human; fig 2
Thomassen M, Gunnarsson T, Christensen P, Pavlovic D, Shattock M, Bangsbo J. Intensive training and reduced volume increases muscle FXYD1 expression and phosphorylation at rest and during exercise in athletes. Am J Physiol Regul Integr Comp Physiol. 2016;310:R659-69 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Haas L, Salazar S, Kostylev M, Um J, Kaufman A, Strittmatter S. Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease. Brain. 2016;139:526-46 pubmed publisher
  • western blot; human; fig 4b
Fonseca B, Zakaria C, Jia J, Graber T, Svitkin Y, Tahmasebi S, et al. La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1). J Biol Chem. 2015;290:15996-6020 pubmed publisher
  • western blot; human
Wnorowski A, Sadowska M, Paul R, Singh N, Boguszewska Czubara A, Jimenez L, et al. Activation of β2-adrenergic receptor by (R,R')-4'-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells. Cell Signal. 2015;27:997-1007 pubmed publisher
  • western blot; mouse
Kettenbach A, Sano H, Keller S, Lienhard G, Gerber S. SPECHT - single-stage phosphopeptide enrichment and stable-isotope chemical tagging: quantitative phosphoproteomics of insulin action in muscle. J Proteomics. 2015;114:48-60 pubmed publisher
  • western blot; mouse; 1:1000
Areta J, Hawley J, Ye J, Chan M, Coffey V. Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells. Nutr Res. 2014;34:1000-7 pubmed publisher
  • western blot; human
Tavares C, Ferguson S, Giles D, Wang Q, Wellmann R, O Brien J, et al. The molecular mechanism of eukaryotic elongation factor 2 kinase activation. J Biol Chem. 2014;289:23901-16 pubmed publisher
  • western blot; rat; 1:1000; fig 2
  • western blot; mouse; 1:1000; fig 5
  • western blot; human; 1:1000; fig 7
Whittington R, Bretteville A, Virag L, Emala C, Maurin T, Marcouiller F, et al. Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation. Sci Rep. 2013;3:1388 pubmed publisher
  • western blot; mouse; fig 4
Alsted T, Ploug T, Prats C, Serup A, Høeg L, Schjerling P, et al. Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle. J Physiol. 2013;591:5141-55 pubmed publisher
  • western blot; human; fig 1
Areta J, Burke L, Ross M, Camera D, West D, Broad E, et al. Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. J Physiol. 2013;591:2319-31 pubmed publisher
Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci. 2016;17: pubmed publisher
Ulasov I, Shah N, Kaverina N, Lee H, Lin B, Lieber A, et al. Tamoxifen improves cytopathic effect of oncolytic adenovirus in primary glioblastoma cells mediated through autophagy. Oncotarget. 2015;6:3977-87 pubmed
Bian J, Wu N, Su R, Li J. Phosphatidylethanolamine-binding protein is not involved in µ-opioid receptor-mediated regulation of extracellular signal-regulated kinase. Mol Med Rep. 2015;11:3368-74 pubmed publisher
Neumann C, Bigliardi Qi M, Widmann C, Bigliardi P. The δ-opioid receptor affects epidermal homeostasis via ERK-dependent inhibition of transcription factor POU2F3. J Invest Dermatol. 2015;135:471-480 pubmed publisher
Bigliardi P, Neumann C, Teo Y, Pant A, Bigliardi Qi M. Activation of the ?-opioid receptor promotes cutaneous wound healing by affecting keratinocyte intercellular adhesion and migration. Br J Pharmacol. 2015;172:501-14 pubmed publisher
Rohailla S, Clarizia N, Sourour M, Sourour W, Gelber N, Wei C, et al. Acute, delayed and chronic remote ischemic conditioning is associated with downregulation of mTOR and enhanced autophagy signaling. PLoS ONE. 2014;9:e111291 pubmed publisher
Reimers J, Loweth J, Wolf M. BDNF contributes to both rapid and homeostatic alterations in AMPA receptor surface expression in nucleus accumbens medium spiny neurons. Eur J Neurosci. 2014;39:1159-69 pubmed publisher
Xue W, Zhou X, Yi N, Jiang L, Tao W, Wu R, et al. Yueju pill rapidly induces antidepressant-like effects and acutely enhances BDNF expression in mouse brain. Evid Based Complement Alternat Med. 2013;2013:184367 pubmed publisher
Teplova I, Lozy F, Price S, Singh S, Barnard N, Cardiff R, et al. ATG proteins mediate efferocytosis and suppress inflammation in mammary involution. Autophagy. 2013;9:459-75 pubmed publisher
Jensen T, Leutert R, Rasmussen S, Mouatt J, Christiansen M, Jensen B, et al. EMG-normalised kinase activation during exercise is higher in human gastrocnemius compared to soleus muscle. PLoS ONE. 2012;7:e31054 pubmed publisher
Thomson D, Hancock C, Evanson B, Kenney S, Malan B, Mongillo A, et al. Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice. J Appl Physiol (1985). 2010;108:1775-85 pubmed publisher
Peng S, Zhang Y, Zhang J, Wang H, Ren B. ERK in learning and memory: a review of recent research. Int J Mol Sci. 2010;11:222-32 pubmed publisher
Bensaad K, Cheung E, Vousden K. Modulation of intracellular ROS levels by TIGAR controls autophagy. EMBO J. 2009;28:3015-26 pubmed publisher
Broom O, Zhang Y, Oldenborg P, Massoumi R, Sjölander A. CD47 regulates collagen I-induced cyclooxygenase-2 expression and intestinal epithelial cell migration. PLoS ONE. 2009;4:e6371 pubmed publisher
product information
SKU :
2331S
Product-Name :
Phospho-eEF2 (Thr56) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, C
Applications :
Western blot
Product-Category :
Translational Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
95
Host :
Rabbit
Target :
eEF2 (Thr57) phosphate
Primary-Protein :
eEF-2
Alt-Names :
EEF-2,EEF2,EF-2,EF2,Elongation factor 2,eukaryotic translation elongation factor 2,polypeptidyl-tRNA translocase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.