product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
c-Jun (L70B11) Mouse mAb
catalog :
2315
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L70B11
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 5a
Xue Z, Vis D, Bruna A, Sustic T, van Wageningen S, Batra A, et al. MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models. Cell Res. 2018;28:719-729 pubmed publisher
  • western blot; rat; loading ...; fig 5c
Chambers T, Santiesteban L, Gomez D, Chambers J. Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity. Toxicology. 2017;382:24-35 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 6g
Fallahi Sichani M, Becker V, Izar B, Baker G, Lin J, Boswell S, et al. Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state. Mol Syst Biol. 2017;13:905 pubmed publisher
  • western blot; human; loading ...; fig 6c
Xiao B, Chen D, Luo S, Hao W, Jing F, Liu T, et al. Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. Oncotarget. 2016;7:50057-50073 pubmed publisher
  • western blot; rat; 1:200; fig 2
Rubattu S, Di Castro S, Schulz H, Geurts A, Cotugno M, Bianchi F, et al. Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. J Am Heart Assoc. 2016;5: pubmed publisher
  • western blot; rat; fig 4b
Smith C, D Mello S. Cell and Context-Dependent Effects of the Heat Shock Protein DNAJB6 on Neuronal Survival. Mol Neurobiol. 2016;53:5628-39 pubmed publisher
  • western blot; human; fig 2
Martinez N, Agosto L, Qiu J, Mallory M, Gazzara M, Barash Y, et al. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev. 2015;29:2054-66 pubmed publisher
  • western blot; human; fig 5
Peiris Pagès M, Sotgia F, Lisanti M. Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells. Oncotarget. 2015;6:10728-45 pubmed
  • immunocytochemistry; human; 1:200
Fallahi Sichani M, Moerke N, Niepel M, Zhang T, Gray N, Sorger P. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Mol Syst Biol. 2015;11:797 pubmed publisher
Schattauer S, Land B, Reichard K, Abraham A, Burgeno L, Kuhar J, et al. Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase. Nat Commun. 2017;8:743 pubmed publisher
Liu Y, Long Y, Xing Z, Zhang D. C-Jun recruits the NSL complex to regulate its target gene expression by modulating H4K16 acetylation and promoting the release of the repressive NuRD complex. Oncotarget. 2015;6:14497-506 pubmed
Gendron L, Mittal N, Beaudry H, Walwyn W. Recent advances on the ? opioid receptor: from trafficking to function. Br J Pharmacol. 2015;172:403-19 pubmed publisher
Tsoi H, Yu A, Chen Z, Ng N, Chan A, Yuen L, et al. A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia. J Med Genet. 2014;51:590-5 pubmed publisher
Ju L, Zhang G, Zhang X, Jia Z, Gao X, Jiang Y, et al. Proteomic analysis of cellular response induced by multi-walled carbon nanotubes exposure in A549 cells. PLoS ONE. 2014;9:e84974 pubmed publisher
Adhikary S, Kocieda V, Yen J, Tuma R, Ganea D. Signaling through cannabinoid receptor 2 suppresses murine dendritic cell migration by inhibiting matrix metalloproteinase 9 expression. Blood. 2012;120:3741-9 pubmed publisher
Takaoka Y, Shimizu Y, Hasegawa H, Ouchi Y, Qiao S, Nagahara M, et al. Forced expression of miR-143 represses ERK5/c-Myc and p68/p72 signaling in concert with miR-145 in gut tumors of Apc(Min) mice. PLoS ONE. 2012;7:e42137 pubmed publisher
Liang J, Wang J, Saad Y, Warble L, Becerra E, Kolattukudy P. Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines. J Neuroinflammation. 2011;8:182 pubmed publisher
Liang F, Kina S, Takemoto H, Matayoshi A, Phonaphonh T, Sunagawa N, et al. HPV16E6-dependent c-fos expression contributes to AP-1 complex formation in SiHa cells. Mediators Inflamm. 2011;2011:263216 pubmed publisher
product information
SKU :
2315S
Product-Name :
c-Jun (L70B11) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
43, 48
Host :
Mouse
Target :
JUN
Primary-Protein :
Jun
Alt-Names :
AP-1,AP1,Activator protein 1,JUN,Jun activation domain binding protein,Proto-oncogene c-Jun,Transcription factor AP-1,V-jun avian sarcoma virus 17 oncogene homolog,c-Jun,enhancer-binding protein AP1,jun oncogene,p39,v-jun sarcoma virus 17 oncogene homolog
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.