product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PP2A B Subunit (100C1) Rabbit mAb
catalog :
2290
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
100C1
reactivity :
human, mouse, rat, cow, fruit fly
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; fruit fly; fig 4b
Williams B, Filter J, Blake Hodek K, Wadzinski B, Fuda N, Shalloway D, et al. Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers. elife. 2014;3:e01695 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
  • western blot; human; 1:1000; fig s7
Yu C, Ji S, Sha Q, Sun Q, Fan H. CRL4-DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation. Nat Commun. 2015;6:8017 pubmed publisher
  • western blot; rat
Kolupaeva V, Daempfling L, Basilico C. The B55? regulatory subunit of protein phosphatase 2A mediates fibroblast growth factor-induced p107 dephosphorylation and growth arrest in chondrocytes. Mol Cell Biol. 2013;33:2865-78 pubmed publisher
Sá F, Lima Leopoldo A, Jacobsen B, Ferron A, Estevam W, Campos D, et al. Obesity Resistance Promotes Mild Contractile Dysfunction Associated with Intracellular Ca2+ Handling. Arq Bras Cardiol. 2015;105:588-96 pubmed publisher
Wong P, Feng Y, Wang J, Shi R, Jiang X. Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun. 2015;6:8048 pubmed publisher
Gan X, Zhao G, Huang C, Rowe A, Purdham D, Karmazyn M. Identification of fat mass and obesity associated (FTO) protein expression in cardiomyocytes: regulation by leptin and its contribution to leptin-induced hypertrophy. PLoS ONE. 2013;8:e74235 pubmed publisher
Kurimchak A, Haines D, Garriga J, Wu S, De Luca F, Sweredoski M, et al. Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55? holoenzyme. Mol Cell Biol. 2013;33:3330-42 pubmed publisher
McConnell B, Koto K, Gutierrez Hartmann A. Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression. Mol Cancer. 2011;10:75 pubmed publisher
product information
SKU :
2290P
Product-Name :
PP2A B Subunit (100C1) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk, Dm, (C, B, Pg)
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
52
Host :
Rabbit
Target :
PP2A B subunit
Primary-Protein :
PPP2R2A
Alt-Names :
2ABA,B55A,B55ALPHA,DKFZp686N05117,FLJ26613,FLJ41727,MGC52248,PP2A subunit B isoform B55-alpha,PP2A subunit B isoform PR55-alpha,PP2A subunit B isoform R2-alpha,PP2A subunit B isoform alpha,PPP2R2A,PR52A,PR55A,protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform,protein phosphatase 2, regulatory subunit B, alpha,serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, alpha isoform
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.