product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cathepsin D Antibody
catalog :
2284
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4e
Wang H, Bu L, Wang C, Zhang Y, Zhou H, Zhang X, et al. The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein-Barr virus by inhibiting the molecular chaperone function of Hsp70. Cell Death Dis. 2018;9:734 pubmed publisher
  • western blot; human; loading ...; fig 4c
Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 2b
Shi B, Huang Q, Birkett R, Doyle R, Dorfleutner A, Stehlik C, et al. SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages. Autophagy. 2017;13:285-301 pubmed publisher
  • immunocytochemistry; human; 1:50; fig s3
Walenbergh S, Houben T, Rensen S, Bieghs V, Hendrikx T, van Gorp P, et al. Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention. Sci Rep. 2016;6:38278 pubmed publisher
  • western blot; human; 1:1000; fig 7
Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed publisher
  • immunocytochemistry; human
  • western blot; human; fig 3e
Ju X, Yan Y, Liu Q, Li N, Sheng M, Zhang L, et al. Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture. J Virol. 2015;89:10347-58 pubmed publisher
  • western blot; mouse; fig 2
Li S, Wang W, Niu T, Wang H, Li B, Shao L, et al. Nrf2 deficiency exaggerates doxorubicin-induced cardiotoxicity and cardiac dysfunction. Oxid Med Cell Longev. 2014;2014:748524 pubmed publisher
Harpsøe K, Isberg V, Tehan B, WEISS D, Arsova A, Marshall F, et al. Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants. Sci Rep. 2015;5:13869 pubmed publisher
Dikshit N, Bist P, Fenlon S, Pulloor N, Chua C, Scidmore M, et al. Intracellular Uropathogenic E. coli Exploits Host Rab35 for Iron Acquisition and Survival within Urinary Bladder Cells. PLoS Pathog. 2015;11:e1005083 pubmed publisher
Gao L, She H, Li W, Zeng J, Zhu J, Jones D, et al. Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease. Antioxid Redox Signal. 2014;20:2936-48 pubmed publisher
product information
SKU :
2284S
Product-Name :
Cathepsin D Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk
Applications :
Flow cytometry
Product-Category :
Adhesion/ECM
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
46, 43, 28
Host :
Rabbit
Target :
Cathepsin D
Primary-Protein :
CTSD
Alt-Names :
CATD,CLN10,CPSD,CTSD,Cathepsin D,Cathepsin D heavy chain,Cathepsin D light chain,MGC2311,ceroid-lipofuscinosis, neuronal 10,lysosomal aspartyl peptidase,lysosomal aspartyl protease
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.