product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Myc-Tag (71D10) Rabbit mAb
catalog :
2278
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
71D10
reactivity :
human, mouse, rat, fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - free floating section
citations: 76
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - free floating section; fruit fly; 1:200; loading ...
Ashley J, Sorrentino V, Lobb Rabe M, Nagarkar Jaiswal S, Tan L, Xu S, et al. Transsynaptic interactions between IgSF proteins DIP-α and Dpr10 are required for motor neuron targeting specificity. elife. 2019;8: pubmed publisher
  • western blot; human; fig 3
Wang Y, Sun H, Wang J, Wang H, Meng L, Xu C, et al. DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity. Cell Death Dis. 2016;7:e2316 pubmed publisher
  • western blot; human; 1:1000; fig s1
Gu X, Mao X, Lussier M, Hutchison M, Zhou L, Hamra F, et al. GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons. Nat Commun. 2016;7:10873 pubmed publisher
  • western blot; scFv; fig 2
Hoa L, Kulaberoglu Y, Gundogdu R, Cook D, Mavis M, Gomez M, et al. The characterisation of LATS2 kinase regulation in Hippo-YAP signalling. Cell Signal. 2016;28:488-497 pubmed publisher
  • western blot; scFv; fig 4
Dai X, Zhuang L, Wang D, Zhou T, Chang L, Gai R, et al. Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells. Oncotarget. 2016;7:6933-47 pubmed publisher
  • western blot; human; fig 9
Yu C, Liang J, Li J, Lee Y, Chang B, Su C, et al. Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathog. 2015;11:e1005350 pubmed publisher
  • immunohistochemistry; scFv; fig 2
He Q, Liu K, Tian Z, Du S. The Effects of Hsp90α1 Mutations on Myosin Thick Filament Organization. PLoS ONE. 2015;10:e0142573 pubmed publisher
  • western blot; human; fig 3a
Hochrainer K, Pejanovic N, Olaseun V, Zhang S, Iadecola C, Anrather J. The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation. Nucleic Acids Res. 2015;43:9889-904 pubmed publisher
  • western blot; scFv; fig 2
Lv X, Wu W, Tang X, Wu Y, Zhu Y, Liu Y, et al. Regulation of SOX10 stability via ubiquitination-mediated degradation by Fbxw7α modulates melanoma cell migration. Oncotarget. 2015;6:36370-82 pubmed publisher
  • immunocytochemistry; scFv; 1:500; fig 7
  • western blot; scFv; 1:1000; fig 7
Choi I, Kim B, Byun J, Baik S, Huh Y, Kim J, et al. LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase. Nat Commun. 2015;6:8255 pubmed publisher
  • western blot; scFv; 1:1000; fig 3
Zhu C, Chen C, Huang J, Zhang H, Zhao X, Deng R, et al. SUMOylation at K707 of DGCR8 controls direct function of primary microRNA. Nucleic Acids Res. 2015;43:7945-60 pubmed publisher
  • western blot; rat; fig 6a
Pedros C, Gaud G, Bernard I, Kassem S, Chabod M, Lagrange D, et al. An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development. J Immunol. 2015;195:1608-16 pubmed publisher
  • western blot; scFv; fig 1
Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed
  • western blot; scFv
Tang X, Chen X, Xu Y, Qiao Y, Zhang X, Wang Y, et al. CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells. Cell Signal. 2015;27:1694-702 pubmed publisher
  • western blot; scFv; fig s4
He R, Peng J, Yuan P, Xu F, Wei W. Divergent roles of BECN1 in LC3 lipidation and autophagosomal function. Autophagy. 2015;11:740-7 pubmed publisher
  • immunocytochemistry; scFv; 1:200
  • western blot; scFv; 1:1000
Bunse L, Schumacher T, Sahm F, Pusch S, Oezen I, Rauschenbach K, et al. Proximity ligation assay evaluates IDH1R132H presentation in gliomas. J Clin Invest. 2015;125:593-606 pubmed publisher
  • immunoprecipitation; scFv
Norton L, Chen X, Fourcaudot M, Acharya N, DeFronzo R, Heikkinen S. The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells. Nucleic Acids Res. 2014;42:13646-61 pubmed publisher
  • western blot; human; 1:1000; fig s2
Tsoi H, Yu A, Chen Z, Ng N, Chan A, Yuen L, et al. A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia. J Med Genet. 2014;51:590-5 pubmed publisher
  • immunoprecipitation; human
  • western blot; human
Zhang B, Cui S, Bai X, Zhuo L, Sun X, Hong Q, et al. SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3-FOXO1 signaling pathway. Age (Dordr). 2013;35:2237-53 pubmed publisher
  • immunoprecipitation; human
  • western blot; human
  • immunoprecipitation; mouse
  • western blot; mouse
Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon A, et al. A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. Blood. 2012;119:1935-45 pubmed publisher
  • western blot; scFv
Tanida I, Yamasaki M, Komatsu M, Ueno T. The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation. Autophagy. 2012;8:88-97 pubmed publisher
Duan J, Pandey S, Li T, Castellano D, Gu X, Li J, et al. Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development. Front Cell Neurosci. 2019;13:217 pubmed publisher
Mokuda S, Nakamichi R, Matsuzaki T, Ito Y, Sato T, Miyata K, et al. Wwp2 maintains cartilage homeostasis through regulation of Adamts5. Nat Commun. 2019;10:2429 pubmed publisher
Bunda S, Heir P, Metcalf J, Li A, Agnihotri S, Pusch S, et al. CIC protein instability contributes to tumorigenesis in glioblastoma. Nat Commun. 2019;10:661 pubmed publisher
Sager R, Woodford M, Backe S, Makedon A, Baker Williams A, DiGregorio B, et al. Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90. Cell Rep. 2019;26:1344-1356.e5 pubmed publisher
Sbrissa D, Semaan L, Govindarajan B, Li Y, Caruthers N, Stemmer P, et al. A novel cross-talk between CXCR4 and PI4KIIIα in prostate cancer cells. Oncogene. 2019;38:332-344 pubmed publisher
Noy P, Gavin R, Colombo D, Haining E, Reyat J, Payne H, et al. Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells. Haematologica. 2018;: pubmed publisher
Grozdanov P, Masoumzadeh E, Latham M, MacDonald C. The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity. Nucleic Acids Res. 2018;46:12022-12039 pubmed publisher
Fort L, Batista J, Thomason P, Spence H, Whitelaw J, Tweedy L, et al. Fam49/CYRI interacts with Rac1 and locally suppresses protrusions. Nat Cell Biol. 2018;20:1159-1171 pubmed publisher
Tonn Eisinger K, Woolfrey K, Swanson S, Schnell S, Meitzen J, DELL ACQUA M, et al. Palmitoylation of caveolin-1 is regulated by the same DHHC acyltransferases that modify steroid hormone receptors. J Biol Chem. 2018;293:15901-15911 pubmed publisher
Mirman Z, Lottersberger F, Takai H, Kibe T, Gong Y, Takai K, et al. 53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in. Nature. 2018;560:112-116 pubmed publisher
Kaneko S, Li X. X chromosome protects against bladder cancer in females via a KDM6A-dependent epigenetic mechanism. Sci Adv. 2018;4:eaar5598 pubmed publisher
Kendall G, Watson S, Xu L, LaVigne C, Murchison W, Rakheja D, et al. PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. elife. 2018;7: pubmed publisher
Razidlo G, Burton K, McNiven M. Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. J Biol Chem. 2018;293:11143-11153 pubmed publisher
Ford C, NANS A, Boucrot E, Hayward R. Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entry. PLoS Pathog. 2018;14:e1007051 pubmed publisher
Li W, Tam K, Chan W, Koon A, Ngo J, Chan H, et al. Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1. J Biol Chem. 2018;293:7674-7688 pubmed publisher
Lokau J, Garbers C. The length of the interleukin-11 receptor stalk determines its capacity for classic signaling. J Biol Chem. 2018;293:6398-6409 pubmed publisher
Serio J, Ropa J, Chen W, Mysliwski M, Saha N, Chen L, et al. The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia. Oncogene. 2018;37:450-460 pubmed publisher
Kumar S, Nakashizuka H, Jones A, Lambert A, Zhao X, Shen M, et al. Proteolytic Degradation and Inflammation Play Critical Roles in Polypoidal Choroidal Vasculopathy. Am J Pathol. 2017;187:2841-2857 pubmed publisher
He R, Peng J, Yuan P, Yang J, Wu X, Wang Y, et al. Glucosyltransferase Activity of Clostridium difficile Toxin B Triggers Autophagy-mediated Cell Growth Arrest. Sci Rep. 2017;7:10532 pubmed publisher
Zhang C, Lai M, Khandan L, Lee L, Chen Z, Junge H. Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function. Nat Commun. 2017;8:16050 pubmed publisher
Hummel T, Ackfeld T, Schönberg M, Ciupka G, Schulz F, Oberdoerster A, et al. Synthetic Deletion of the Interleukin 23 Receptor (IL-23R) Stalk Region Led to Autonomous IL-23R Homodimerization and Activation. Mol Cell Biol. 2017;37: pubmed publisher
Ji L, Jiang B, Jiang X, Charlat O, Chen A, Mickanin C, et al. The SIAH E3 ubiquitin ligases promote Wnt/?-catenin signaling through mediating Wnt-induced Axin degradation. Genes Dev. 2017;31:904-915 pubmed publisher
Wetendorf M, Wu S, Wang X, Creighton C, Wang T, Lanz R, et al. Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment. Biol Reprod. 2017;96:313-326 pubmed publisher
Schou K, Mogensen J, Morthorst S, Nielsen B, Aleliunaite A, Serra Marques A, et al. KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling. Nat Commun. 2017;8:14177 pubmed publisher
Kidger A, Rushworth L, Stellzig J, Davidson J, Bryant C, Bayley C, et al. Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling. Proc Natl Acad Sci U S A. 2017;114:E317-E326 pubmed publisher
Fontana G, Rigamonti A, Lenzken S, Filosa G, Alvarez R, Calogero R, et al. Oxidative stress controls the choice of alternative last exons via a Brahma-BRCA1-CstF pathway. Nucleic Acids Res. 2017;45:902-914 pubmed publisher
Dreer M, Fertey J, van de Poel S, Straub E, Madlung J, Macek B, et al. Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication. PLoS Pathog. 2016;12:e1005556 pubmed publisher
Lee D, Wang Y, Kalaitzidis D, Ramachandran J, Eda H, Sykes D, et al. Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy. J Clin Invest. 2016;126:1300-10 pubmed publisher
Ganesan S, Falla A, Goldfless S, Nasamu A, Niles J. Synthetic RNA-protein modules integrated with native translation mechanisms to control gene expression in malaria parasites. Nat Commun. 2016;7:10727 pubmed publisher
Shin H, Park E, Yun S, Kim S, Jung W, Woo S, et al. p31comet-Induced Cell Death Is Mediated by Binding and Inactivation of Mad2. PLoS ONE. 2015;10:e0141523 pubmed publisher
Miesfeld J, Gestri G, Clark B, Flinn M, Poole R, Bader J, et al. Yap and Taz regulate retinal pigment epithelial cell fate. Development. 2015;142:3021-32 pubmed publisher
Abrams A, Hufnagel R, Rebelo A, Zanna C, Patel N, Gonzalez M, et al. Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder. Nat Genet. 2015;47:926-32 pubmed publisher
Moon J, Hisata S, Park M, DeNicola G, Ryter S, Nakahira K, et al. mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation. Cell Rep. 2015;12:102-115 pubmed publisher
Toruń A, Szymańska E, Castanon I, Wolińska Nizioł L, Bartosik A, Jastrzębski K, et al. Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling. PLoS ONE. 2015;10:e0130818 pubmed publisher
Ma P, Foote D, Sinnamon A, Brass L. Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1). PLoS ONE. 2015;10:e0119496 pubmed publisher
Wang Y, Zhang Y, Zhu Y, Zhang P. Lipolytic inhibitor G0/G1 switch gene 2 inhibits reactive oxygen species production and apoptosis in endothelial cells. Am J Physiol Cell Physiol. 2015;308:C496-504 pubmed publisher
Mo S, Chiang S, Lai T, Cheng Y, Chung C, Kuo S, et al. Visualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cells. PLoS ONE. 2014;9:e116074 pubmed publisher
Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, et al. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nat Commun. 2014;5:5482 pubmed publisher
Tanida I, Ueno T, Uchiyama Y. A super-ecliptic, pHluorin-mKate2, tandem fluorescent protein-tagged human LC3 for the monitoring of mammalian autophagy. PLoS ONE. 2014;9:e110600 pubmed publisher
Sourvinos G, Morou A, Sanidas I, Codruta I, Ezell S, Doxaki C, et al. The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection. PLoS Pathog. 2014;10:e1004136 pubmed publisher
Yi J, Xiong W, Gong X, Bellister S, Ellis L, Liu Q. Analysis of LGR4 receptor distribution in human and mouse tissues. PLoS ONE. 2013;8:e78144 pubmed publisher
Cheung H, Dunbar C, Mórotz G, Cheng W, Chan H, Miller C, et al. FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth. FASEB J. 2014;28:337-49 pubmed publisher
Higa N, Toma C, Koizumi Y, Nakasone N, Nohara T, Masumoto J, et al. Vibrio parahaemolyticus effector proteins suppress inflammasome activation by interfering with host autophagy signaling. PLoS Pathog. 2013;9:e1003142 pubmed publisher
He H, Mou Z, Li W, Fei L, Tang Y, Zhang J, et al. Proteomic methods reveal cyclophilin A function as a host restriction factor against rotavirus infection. Proteomics. 2013;13:1121-32 pubmed publisher
Tattoli I, Philpott D, Girardin S. The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole. Biol Open. 2012;1:1215-25 pubmed publisher
Savaryn J, Reitsma J, Bigley T, Halligan B, Qian Z, Yu D, et al. Human cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection. J Virol. 2013;87:2463-74 pubmed publisher
Liao W, Zhao R, Lu L, Zhang R, Zou J, Xu T, et al. Overexpression of a novel osteopetrosis-related gene CCDC154 suppresses cell proliferation by inducing G2/M arrest. Cell Cycle. 2012;11:3270-9 pubmed publisher
Song N, Ding Y, Zhuo W, He T, Fu Z, Chen Y, et al. The nuclear translocation of endostatin is mediated by its receptor nucleolin in endothelial cells. Angiogenesis. 2012;15:697-711 pubmed publisher
Petrucelli A, Umashankar M, Zagallo P, Rak M, Goodrum F. Interactions between proteins encoded within the human cytomegalovirus UL133-UL138 locus. J Virol. 2012;86:8653-62 pubmed publisher
Sommer J, Effenberger T, Volpi E, Waetzig G, Bernhardt M, Suthaus J, et al. Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling. J Biol Chem. 2012;287:13743-51 pubmed publisher
Goel S, Chin E, Fakhraldeen S, Berry S, Beebe D, Alexander C. Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts. J Biol Chem. 2012;287:16454-66 pubmed publisher
Olsen B, Wang S, Svenstrup T, Chen B, Guerra B. Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage. BMC Mol Biol. 2012;13:7 pubmed publisher
Zhu Z, Kremer P, Tadmori I, Ren Y, Sun D, He X, et al. Lithium suppresses astrogliogenesis by neural stem and progenitor cells by inhibiting STAT3 pathway independently of glycogen synthase kinase 3 beta. PLoS ONE. 2011;6:e23341 pubmed publisher
Welcker M, Clurman B. Fbw7/hCDC4 dimerization regulates its substrate interactions. Cell Div. 2007;2:7 pubmed
Takizawa N, Smith T, Nebl T, Crowley J, Palmieri S, Lifshitz L, et al. Supervillin modulation of focal adhesions involving TRIP6/ZRP-1. J Cell Biol. 2006;174:447-58 pubmed
product information
SKU :
2278P
Product-Name :
Myc-Tag (71D10) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
All
Applications :
Flow cytometry
Product-Category :
Related Products
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
Myc Tag
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.