product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Shh/Ihh Antibody
catalog :
2271
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
citations: 29
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4
Chen Y, Wei M, Wang C, Lee H, Pan S, Gao M, et al. Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer. Cancer Lett. 2015;357:582-90 pubmed publisher
Rodgers S, Ferguson D, Mitchell C, Ooms L. Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases. Biosci Rep. 2017;37: pubmed publisher
Amoroso M, Matassa D, Agliarulo I, Avolio R, Lu H, Sisinni L, et al. TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial-mesenchymal transition. Cell Death Dis. 2016;7:e2522 pubmed publisher
Yuan F, XU M, Li X, Xinlong H, Fang W, Dong J. The Roles of Acidosis in Osteoclast Biology. Front Physiol. 2016;7:222 pubmed publisher
Chandra V, Karamitri A, Richards P, Cormier F, Ramond C, Jockers R, et al. Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells. Sci Rep. 2016;6:25765 pubmed publisher
Yu R, Yu B, Chen J, Lv X, Yan Z, Cheng Y, et al. Anti-tumor effects of Atractylenolide I on bladder cancer cells. J Exp Clin Cancer Res. 2016;35:40 pubmed publisher
Wang H, Liu W, Black S, Turner O, Daniel J, Dean Colomb W, et al. Kaiso, a transcriptional repressor, promotes cell migration and invasion of prostate cancer cells through regulation of miR-31 expression. Oncotarget. 2016;7:5677-89 pubmed publisher
Kong D, Li S, Du Z, Liu C, Liu B, Li C, et al. BAG3 elevation inhibits cell proliferation via direct interaction with G6PD in hepatocellular carcinomas. Oncotarget. 2016;7:700-11 pubmed publisher
Tsurumaki H, Mogi C, Aoki Saito H, Tobo M, Kamide Y, Yatomi M, et al. Protective Role of Proton-Sensing TDAG8 in Lipopolysaccharide-Induced Acute Lung Injury. Int J Mol Sci. 2015;16:28931-42 pubmed publisher
Qin H, Sha J, Jiang C, Gao X, Qu L, Yan H, et al. miR-122 inhibits metastasis and epithelial-mesenchymal transition of non-small-cell lung cancer cells. Onco Targets Ther. 2015;8:3175-84 pubmed publisher
Liu M, Qi Z, Liu B, Ren Y, Li H, Yang G, et al. RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway. Oncotarget. 2015;6:25281-94 pubmed publisher
Cohen Solal K, Boregowda R, Lasfar A. RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression. Mol Cancer. 2015;14:137 pubmed publisher
Tobo A, Tobo M, Nakakura T, Ebara M, Tomura H, Mogi C, et al. Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses. PLoS ONE. 2015;10:e0129334 pubmed publisher
Yuan F, Zhao M, Jiang L, Wang H, Cao L, Zhou X, et al. Molecular actions of ovarian cancer G protein-coupled receptor 1 caused by extracellular acidification in bone. Int J Mol Sci. 2014;15:22365-73 pubmed publisher
Park M, Kim B, Dong S, Lee S, Kim D, Rho S. The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1? expression. Oncotarget. 2014;5:4935-44 pubmed
Ren W, Liu Y, Wan S, Fei C, Wang W, Chen Y, et al. BMP9 inhibits proliferation and metastasis of HER2-positive SK-BR-3 breast cancer cells through ERK1/2 and PI3K/AKT pathways. PLoS ONE. 2014;9:e96816 pubmed publisher
Muniz Feliciano L, Van Grol J, Portillo J, Liew L, Liu B, Carlin C, et al. Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the parasite. PLoS Pathog. 2013;9:e1003809 pubmed publisher
Song T, Wang L, Mo Z, Mao L, Ma X, Niu R, et al. Expression of p-Akt in ovarian serous carcinoma and its association with proliferation and apoptosis. Oncol Lett. 2014;7:59-64 pubmed
Juvin V, Malek M, Anderson K, Dion C, Chessa T, Lecureuil C, et al. Signaling via class IA Phosphoinositide 3-kinases (PI3K) in human, breast-derived cell lines. PLoS ONE. 2013;8:e75045 pubmed publisher
Leal P, Garcia P, Sandoval A, Buchegger K, Weber H, Tapia O, et al. AKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines. Onco Targets Ther. 2013;6:1373-84 pubmed publisher
Dobbin Z, Landen C. The importance of the PI3K/AKT/MTOR pathway in the progression of ovarian cancer. Int J Mol Sci. 2013;14:8213-27 pubmed publisher
De Marco C, Rinaldo N, Bruni P, Malzoni C, Zullo F, Fabiani F, et al. Multiple genetic alterations within the PI3K pathway are responsible for AKT activation in patients with ovarian carcinoma. PLoS ONE. 2013;8:e55362 pubmed publisher
Lee H, Kim J, Kim E. Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways. PLoS ONE. 2012;7:e50624 pubmed publisher
McCubrey J, Steelman L, Chappell W, Abrams S, Montalto G, Cervello M, et al. Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response. Oncotarget. 2012;3:954-87 pubmed
He J, Xu Q, Wang M, Li C, Qian X, Shi Z, et al. Oral administration of apigenin inhibits metastasis through AKT/P70S6K1/MMP-9 pathway in orthotopic ovarian tumor model. Int J Mol Sci. 2012;13:7271-82 pubmed publisher
Virtakoivu R, Pellinen T, Rantala J, Perälä M, Ivaska J. Distinct roles of AKT isoforms in regulating ?1-integrin activity, migration, and invasion in prostate cancer. Mol Biol Cell. 2012;23:3357-69 pubmed publisher
Saji M, Narahara K, McCarty S, Vasko V, La Perle K, Porter K, et al. Akt1 deficiency delays tumor progression, vascular invasion, and distant metastasis in a murine model of thyroid cancer. Oncogene. 2011;30:4307-15 pubmed publisher
Kumar R, Blakemore S, Ellis C, Petricoin E, Pratt D, Macoritto M, et al. Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693. BMC Genomics. 2010;11:419 pubmed publisher
Smith D, Patel S, Raffoul F, Haller E, Mills G, Nanjundan M. Arsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells. Cell Death Differ. 2010;17:1867-81 pubmed publisher
product information
SKU :
2271S
Product-Name :
Shh/Ihh Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
M, (H, R)
Applications :
Western blot
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
19, (42, 45)
Host :
Rabbit
Target :
SHH
Primary-Protein :
SHH
Alt-Names :
HHG-1,HHG1,HLP3,HPE3,MCOPCB5,SHH,SMMCI,Sonic hedgehog protein,Sonic hedgehog protein C-product,Sonic hedgehog protein N-product,TPT,TPTPS,sonic hedgehog homolog (Drosophila)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.