product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PP2A C Subunit (52F8) Rabbit mAb
catalog :
2259
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
52F8
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 7a
  • western blot; mouse; fig 6e
Xiao G, Chan L, Klemm L, Braas D, Chen Z, Geng H, et al. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018;173:470-484.e18 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
  • western blot; human; 1:1000; fig s7
Yu C, Ji S, Sha Q, Sun Q, Fan H. CRL4-DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation. Nat Commun. 2015;6:8017 pubmed publisher
  • western blot; mouse; fig 3
Boding L, Hansen A, Meroni G, Johansen B, Braunstein T, Bonefeld C, et al. Midline 1 directs lytic granule exocytosis and cytotoxicity of mouse killer T cells. Eur J Immunol. 2014;44:3109-18 pubmed publisher
  • immunoprecipitation; human; 1:500
  • western blot; human; fig 5
Nakahata S, Ichikawa T, Maneesaay P, Saito Y, Nagai K, Tamura T, et al. Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers. Nat Commun. 2014;5:3393 pubmed publisher
Ishii T, Takanashi Y, Sugita K, Miyazawa M, Yanagihara R, Yasuda K, et al. Endogenous reactive oxygen species cause astrocyte defects and neuronal dysfunctions in the hippocampus: a new model for aging brain. Aging Cell. 2017;16:39-51 pubmed publisher
Crajoinas R, Pessoa T, Rodrigues M, Malnic G, Girardi A. Changes in the activity and expression of protein phosphatase-1 accompany the differential regulation of NHE3 before and after the onset of hypertension in spontaneously hypertensive rats. Acta Physiol (Oxf). 2014;211:395-408 pubmed publisher
Amissah F, Duverna R, Aguilar B, Poku R, Lamango N. Polyisoprenylated methylated protein methyl esterase is both sensitive to curcumin and overexpressed in colorectal cancer: implications for chemoprevention and treatment. Biomed Res Int. 2013;2013:416534 pubmed publisher
Hagen K, Zeng X, Lee M, Tucker Kahn S, Harrison Pitner M, Zaky S, et al. Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis. Cell Div. 2013;8:10 pubmed publisher
Lebedeva G, Sorokin A, Faratian D, Mullen P, Goltsov A, Langdon S, et al. Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network. Eur J Pharm Sci. 2012;46:244-58 pubmed publisher
product information
SKU :
2259P
Product-Name :
PP2A C Subunit (52F8) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk, Dm, (C, Pg)
Applications :
Flow cytometry
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
36, 38
Host :
Rabbit
Target :
PP2A C subunit
Primary-Protein :
PPP2CA
Alt-Names :
PP2A-alpha,PP2AA,PP2Ac,PP2CA,PP2Calpha,PPP2CA,RP-C,Replication protein C,Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform,protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform,protein phosphatase 2, catalytic subunit, alpha isoform,protein phosphatase 2, catalytic subunit, alpha isozyme,protein phosphatase 2A catalytic subunit, alpha isoform,serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.