product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PU.1 (9G7) Rabbit mAb
catalog :
2258
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
9G7
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - free floating section
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4h
Zhu H, Zhang L, Wu Y, Dong B, Guo W, Wang M, et al. T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1. elife. 2018;7: pubmed publisher
  • western blot; human; loading ...; fig 9h
Chennupati V, Veiga D, Maslowski K, Andina N, Tardivel A, Yu E, et al. Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation. J Clin Invest. 2018;128:1597-1614 pubmed publisher
  • western blot; human; fig 5e
Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 2c
Wei S, Zhao M, Wang X, Li Y, Wang K. PU.1 controls the expression of long noncoding RNA HOTAIRM1 during granulocytic differentiation. J Hematol Oncol. 2016;9:44 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s2a
Burda P, Vargova J, Curik N, Salek C, Papadopoulos G, Strouboulis J, et al. GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in Erythroleukemia. PLoS ONE. 2016;11:e0152234 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
  • western blot; human
Bunaciu R, Jensen H, Macdonald R, Latocha D, Varner J, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. PLoS ONE. 2015;10:e0135668 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:400; tbl 1
Almolda B, de Labra C, Barrera I, Gruart A, Delgado Garcia J, Villacampa N, et al. Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10. Brain Behav Immun. 2015;45:80-97 pubmed publisher
Weng H, Huang H, Wu H, Qin X, Zhao B, Dong L, et al. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018;22:191-205.e9 pubmed publisher
Mohr S, Doebele C, Comoglio F, Berg T, Beck J, Bohnenberger H, et al. Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. Cancer Cell. 2017;31:549-562.e11 pubmed publisher
Su M, Cao J, Huang J, Liu S, Im D, Yoo J, et al. The In Vitro and In Vivo Anti-Inflammatory Effects of a Phthalimide PPAR-? Agonist. Mar Drugs. 2017;15: pubmed publisher
Bahram F, Hydbring P, Tronnersjö S, Zakaria S, Frings O, Fahlén S, et al. Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation. Oncotarget. 2016;7:2837-54 pubmed publisher
Smith A, Graham E, Feng S, Oldfield R, Bergin P, Mee E, et al. Adult human glia, pericytes and meningeal fibroblasts respond similarly to IFNy but not to TGF?1 or M-CSF. PLoS ONE. 2013;8:e80463 pubmed publisher
Smith A, Gibbons H, Oldfield R, Bergin P, Mee E, Curtis M, et al. M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia. J Neuroinflammation. 2013;10:85 pubmed publisher
Wilkinson A, Ballabio E, Geng H, North P, Tapia M, Kerry J, et al. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction. Cell Rep. 2013;3:116-27 pubmed publisher
Martin T, Jayanthi S, McCoy M, Brannock C, Ladenheim B, Garrett T, et al. Methamphetamine causes differential alterations in gene expression and patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens. PLoS ONE. 2012;7:e34236 pubmed publisher
Worm J, Stenvang J, Petri A, Frederiksen K, Obad S, Elmen J, et al. Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF. Nucleic Acids Res. 2009;37:5784-92 pubmed publisher
product information
SKU :
2258S
Product-Name :
PU.1 (9G7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, (Mk, Pg)
Applications :
Chromatin Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
42
Host :
Rabbit
Target :
PU.1
Primary-Protein :
PU.1
Alt-Names :
31 kDa transforming protein,31 kDa-transforming protein,OF,PU.1,SFPI1,SPI-1,SPI-1 proto-oncogene,SPI-A,SPI1,Transcription factor PU.1,hematopoietic transcription factor PU.1,spleen focus forming virus (SFFV) proviral integration oncogene spi1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.