product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PRMT5/Skb1Hs Methyltransferase Antibody
catalog :
2252
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1b, 6a
Yang C, Chiu L, Chang C, Chuang H, Tan T. Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation. FASEB J. 2018;:fj201800244RR pubmed publisher
  • western blot; human; loading ...; fig 1d
Clarke T, Sanchez Bailon M, Chiang K, Reynolds J, Herrero Ruiz J, Bandeiras T, et al. PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination. Mol Cell. 2017;65:900-916.e7 pubmed publisher
  • western blot; human; fig 1
Mounir Z, Korn J, Westerling T, Lin F, Kirby C, Schirle M, et al. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor. elife. 2016;5: pubmed publisher
Yu S, Wang Y, Yuan H, Zhao H, Lv W, Chen J, et al. Knockdown of Mediator Complex Subunit 19 Suppresses the Growth and Invasion of Prostate Cancer Cells. PLoS ONE. 2017;12:e0171134 pubmed publisher
Poh A, O Donoghue R, Ernst M. Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells. Oncotarget. 2015;6:15752-71 pubmed
Nicholas C, Yang J, Peters S, Bill M, Baiocchi R, Yan F, et al. PRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.). PLoS ONE. 2013;8:e74710 pubmed publisher
St Pierre J, Ostergaard H. A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation. PLoS ONE. 2013;8:e71531 pubmed publisher
product information
SKU :
2252S
Product-Name :
PRMT5/Skb1Hs Methyltransferase Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
70
Host :
Rabbit
Target :
PRMT5
Primary-Protein :
PRMT5
Alt-Names :
72 kDa ICln-binding protein,ANM5,HMT1 hnRNP methyltransferase-like 5,HRMT1L5,Histone-arginine N-methyltransferase PRMT5,IBP72,JBP1,Jak-binding protein 1,PRMT5,Protein arginine N-methyltransferase 5,SKB1,SKB1 homolog,SKB1Hs,Shk1 kinase-binding protein 1 homolog,protein arginine methyltransferase 5
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.