product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
FosB (5G4) Rabbit mAb
catalog :
2251
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
5G4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 2c
Vallejo A, Perurena N, Guruceaga E, Mazur P, Martínez Canarias S, Zandueta C, et al. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nat Commun. 2017;8:14294 pubmed publisher
  • western blot; human; 1:1000
Carthy J, Sundqvist A, Heldin A, van Dam H, Kletsas D, Heldin C, et al. Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2. J Cell Physiol. 2015;230:3084-92 pubmed publisher
  • chromatin immunoprecipitation; human; fig 2
  • immunocytochemistry; human; fig 7
  • western blot; human; fig 1
Butin Israeli V, Adam S, Jain N, Otte G, Neems D, Wiesmüller L, et al. Role of lamin b1 in chromatin instability. Mol Cell Biol. 2015;35:884-98 pubmed publisher
  • western blot; mouse; 1:500
Yan T, Li L, Sun B, Liu F, Yang P, Chen T, et al. Luteolin inhibits behavioral sensitization by blocking methamphetamine-induced MAPK pathway activation in the caudate putamen in mice. PLoS ONE. 2014;9:e98981 pubmed publisher
Gajewski P, Turecki G, ROBISON A. Differential Expression of FosB Proteins and Potential Target Genes in Select Brain Regions of Addiction and Depression Patients. PLoS ONE. 2016;11:e0160355 pubmed publisher
Ho J, Hsu R, Wu C, Liao G, Gao H, Wang T, et al. Reduced miR-550a-3p leads to breast cancer initiation, growth, and metastasis by increasing levels of ERK1 and 2. Oncotarget. 2016;7:53853-53868 pubmed publisher
Liu Y, Xu F, Pei H, Zhu X, Lin X, Song C, et al. Vaspin regulates the osteogenic differentiation of MC3T3-E1 through the PI3K-Akt/miR-34c loop. Sci Rep. 2016;6:25578 pubmed publisher
Liu Z, Cai H, Zheng X, Zhang B, Xia C. The Involvement of Mutual Inhibition of ERK and mTOR in PLCγ1-Mediated MMP-13 Expression in Human Osteoarthritis Chondrocytes. Int J Mol Sci. 2015;16:17857-69 pubmed publisher
Brobeil A, Kämmerer F, Tag C, Steger K, Gattenlöhner S, Wimmer M. PTPIP51—A New RelA-tionship with the NFκB Signaling Pathway. Biomolecules. 2015;5:485-504 pubmed publisher
Zhang Y, Crofton E, Li D, Lobo M, Fan X, Nestler E, et al. Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment. Front Behav Neurosci. 2014;8:297 pubmed publisher
Hamilton G, Abraham A, Morton J, Sampson O, Pefani D, Khoronenkova S, et al. AKT regulates NPM dependent ARF localization and p53mut stability in tumors. Oncotarget. 2014;5:6142-67 pubmed
Li C, Li F, Zhao K, Yao J, Cheng Y, Zhao L, et al. LFG-500 inhibits the invasion of cancer cells via down-regulation of PI3K/AKT/NF-?B signaling pathway. PLoS ONE. 2014;9:e91332 pubmed publisher
Guo S, Li Z, Jiang D, Lu Y, Liu Y, Gao L, et al. IRF4 is a novel mediator for neuronal survival in ischaemic stroke. Cell Death Differ. 2014;21:888-903 pubmed publisher
Huang L, Kondo F, Harato M, Feng G, Ishikawa N, Fujiwara Y, et al. Enhanced expression of WD repeat-containing protein 35 via nuclear factor-kappa B activation in bupivacaine-treated Neuro2a cells. PLoS ONE. 2014;9:e86336 pubmed publisher
Chen Y, Thang M, Chan Y, Huang Y, Ma N, Yu A, et al. Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. PLoS ONE. 2013;8:e82751 pubmed publisher
Yuan F, Chen J, Sun P, Guan S, Xu J. Wedelolactone inhibits LPS-induced pro-inflammation via NF-kappaB pathway in RAW 264.7 cells. J Biomed Sci. 2013;20:84 pubmed publisher
Wickert L, Blanchette J, Waldschmidt N, Bertics P, Denu J, Denlinger L, et al. The C-terminus of human nucleotide receptor P2X7 is critical for receptor oligomerization and N-linked glycosylation. PLoS ONE. 2013;8:e63789 pubmed publisher
Saito T, Uda S, Tsuchiya T, Ozaki Y, Kuroda S. Temporal decoding of MAP kinase and CREB phosphorylation by selective immediate early gene expression. PLoS ONE. 2013;8:e57037 pubmed publisher
Tominaga Yamanaka K, Abdelmohsen K, Martindale J, Yang X, Taub D, Gorospe M. NF90 coordinately represses the senescence-associated secretory phenotype. Aging (Albany NY). 2012;4:695-708 pubmed
Pillon N, Arane K, Bilan P, Chiu T, Klip A. Muscle cells challenged with saturated fatty acids mount an autonomous inflammatory response that activates macrophages. Cell Commun Signal. 2012;10:30 pubmed publisher
Sundar I, Chung S, Hwang J, Lapek J, Bulger M, Friedman A, et al. Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-?B-dependent genes. PLoS ONE. 2012;7:e31378 pubmed publisher
Rahman M, Kundu J, Shin J, Na H, Surh Y. Docosahexaenoic acid inhibits UVB-induced activation of NF-?B and expression of COX-2 and NOX-4 in HR-1 hairless mouse skin by blocking MSK1 signaling. PLoS ONE. 2011;6:e28065 pubmed publisher
Aviello G, Canadanović Brunet J, Milic N, Capasso R, Fattorusso E, Taglialatela Scafati O, et al. Potent antioxidant and genoprotective effects of boeravinone G, a rotenoid isolated from Boerhaavia diffusa. PLoS ONE. 2011;6:e19628 pubmed publisher
Giampietri C, Petrungaro S, Coluccia P, Antonangeli F, Giannakakis K, Faraggiana T, et al. c-Flip overexpression affects satellite cell proliferation and promotes skeletal muscle aging. Cell Death Dis. 2010;1:e38 pubmed publisher
Bitel C, Feng Y, Souayah N, Frederikse P. Increased expression and local accumulation of the prion protein, Alzheimer A? peptides, superoxide dismutase 1, and nitric oxide synthases 1 & 2 in muscle in a rabbit model of diabetes. BMC Physiol. 2010;10:18 pubmed publisher
Jensen T, Schjerling P, Viollet B, Wojtaszewski J, Richter E. AMPK alpha1 activation is required for stimulation of glucose uptake by twitch contraction, but not by H2O2, in mouse skeletal muscle. PLoS ONE. 2008;3:e2102 pubmed publisher
Larson D, Gosse J, Holowka D, Baird B, Webb W. Temporally resolved interactions between antigen-stimulated IgE receptors and Lyn kinase on living cells. J Cell Biol. 2005;171:527-36 pubmed
product information
SKU :
2251S
Product-Name :
FosB (5G4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Chromatin Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
38 FosB2 48 FosB
Host :
Rabbit
Target :
FosB
Primary-Protein :
FosB
Alt-Names :
AP-1,DKFZp686C0818,FBJ murine osteosarcoma viral oncogene homolog B,FOSB,G0/G1 switch regulatory protein 3,G0S3,GOS3,GOSB,MGC42291,Protein fosB,activator protein 1,oncogene FOS-B
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.