Phospho-HER2/ErbB2 (Tyr1221/1222) Antibody | Cell Signaling Technology 2249 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-HER2/ErbB2 (Tyr1221/1222) Antibody

catalog :

2249

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

more info or order :

Cell Signaling Technology product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 3c	Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110Î± loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed publisher
western blot; human; 1:500; fig s2	Deblois G, Smith H, Tam I, Gravel S, Caron M, Savage P, et al. ERR? mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nat Commun. 2016;7:12156 pubmed publisher
western blot; human; loading ...; fig 3b	Teng Y, Pi W, Wang Y, Cowell J. WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling. Oncogene. 2016;35:4633-40 pubmed publisher
western blot; human; loading ...; fig 4a,b	Fumagalli I, Dugue D, Bibault J, ClÃ©menson C, Vozenin M, Mondini M, et al. Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines. Onco Targets Ther. 2015;8:335-45 pubmed publisher
western blot; human; fig 4c	Zhang L, Castanaro C, Luan B, Yang K, Fan L, Fairhurst J, et al. ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models. Mol Cancer Ther. 2014;13:1345-55 pubmed publisher
western blot; human	Hsu F, Yang M, Lin E, Tseng C, Lin H. The significance of Her2 on androgen receptor protein stability in the transition of androgen requirement in prostate cancer cells. Am J Physiol Endocrinol Metab. 2011;300:E902-8 pubmed publisher
	Kitowska K, Kowalska A, Mieszkowska M, Piasecka D, Skladanowski A, Romanska H, et al. Progesterone impairs Herceptin effect on breast cancer cells. Oncol Lett. 2018;15:1817-1822 pubmed publisher
	Prince T, Kijima T, Tatokoro M, Lee S, Tsutsumi S, Yim K, et al. Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants. PLoS ONE. 2015;10:e0141786 pubmed publisher
	Berstad M, Weyergang A, Berg K. Photochemical internalization (PCI) of HER2-targeted toxins: synergy is dependent on the treatment sequence. Biochim Biophys Acta. 2012;1820:1849-58 pubmed publisher

product information

SKU :

2249S

Product-Name :

Phospho-HER2/ErbB2 (Tyr1221/1222) Antibody

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

Applications :

Western blot

Product-Category :

RTK

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

185

Host :

Rabbit

Target :

HER2/ErbB2 (Tyr1221/Tyr1222) phosphate

Primary-Protein :

HER2

Alt-Names :

CD340,ERBB2,HER-2,HER-2/neu,HER2,MLN 19,MLN19,Metastatic lymph node gene 19 protein,NEU,NGL,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Receptor tyrosine-protein kinase erbB-2,TKR1,Tyrosine kinase-type cell surface receptor HER2,c-erb B2/neu protein,erbB-2,herstatin,neuroblastoma/glioblastoma derived oncogene homolog,p185erbB2,v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog),v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

more info or order :

Cell Signaling Technology product webpage