| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 4g
| Ibarra B, Machen C, ATIT R. Wnt-Dependent Activation of ERK Mediates Repression of Chondrocyte Fate during Calvarial Development. J Dev Biol. 2021;9: pubmed publisher |
- immunohistochemistry; mouse; 1:400; loading ...; fig 2a
| Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, et al. Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021;148: pubmed publisher |
- western blot; zebrafish ; 1:1000; fig 1g
| Yi C, Spitters T, Al Far E, Wang S, Xiong T, Cai S, et al. A calcineurin-mediated scaling mechanism that controls a K+-leak channel to regulate morphogen and growth factor transcription. elife. 2021;10: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 2s1a
| Rattner A, Terrillion C, Jou C, Kleven T, Hu S, Williams J, et al. Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus. elife. 2020;9: pubmed publisher |
- immunohistochemistry; mouse; 1:300; loading ...; fig 1a
| Matos I, Asare A, Levorse J, Ouspenskaia T, de la Cruz Racelis J, Schuhmacher L, et al. Progenitors oppositely polarize WNT activators and inhibitors to orchestrate tissue development. elife. 2020;9: pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 7b
| Engelbrecht E, Lévesque M, He L, Vanlandewijck M, Nitzsche A, Niazi H, et al. Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta. elife. 2020;9: pubmed publisher |
- western blot; human; loading ...; fig 5a
| Chen X, Xiong X, Cui D, Yang F, Wei D, Li H, et al. DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals. Oncogene. 2020;39:1557-1571 pubmed publisher |
- immunocytochemistry; mouse; 1:2000; loading ...; fig s4t
- western blot; mouse; 1:1000; loading ...; fig 4i
| Pedone E, Postiglione L, Aulicino F, Rocca D, Montes Olivas S, Khazim M, et al. A tunable dual-input system for on-demand dynamic gene expression regulation. Nat Commun. 2019;10:4481 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher |
- western blot; human; loading ...; fig 4h
| Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, et al. RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer. J Exp Clin Cancer Res. 2019;38:334 pubmed publisher |
- western blot; human; loading ...; fig ex8j
| Parolia A, Cieslik M, Chu S, Xiao L, Ouchi T, Zhang Y, et al. Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer. Nature. 2019;: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 1b
| Wang Y, Sabbagh M, Gu X, Rattner A, Williams J, Nathans J. Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures. elife. 2019;8: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1b
| Krimpenfort P, Snoek M, Lambooij J, Song J, van der Weide R, Bhaskaran R, et al. A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis. Nat Commun. 2019;10:1425 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1a
| Xing S, Gai K, Li X, Shao P, Zeng Z, Zhao X, et al. Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells. J Exp Med. 2019;: pubmed publisher |
- immunohistochemistry - frozen section; human; 1:50; loading ...; fig 6d
| Sahara M, Santoro F, Sohlmér J, Zhou C, Witman N, Leung C, et al. Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract. Dev Cell. 2019;48:475-490.e7 pubmed publisher |
- western blot; human; loading ...; fig 2a
| Zhou L, Jing J, Wang H, Wu X, Lu Z. Decorin promotes proliferation and migration of ORS keratinocytes and maintains hair anagen in mice. Exp Dermatol. 2018;27:1237-1244 pubmed publisher |
- immunohistochemistry; mouse; 1:500; loading ...; fig 7a
| Hoefert J, Bjerke G, Wang D, Yi R. The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. J Cell Biol. 2018;217:2185-2204 pubmed publisher |
- immunocytochemistry; mouse; 1:200; fig 8a
| Yu W, Li X, Eliason S, Romero Bustillos M, Ries R, Cao H, et al. Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation. Dev Biol. 2017;429:44-55 pubmed publisher |
- western blot; human; loading ...; fig 6c
| Subramaniam M, Cicek M, Pitel K, Bruinsma E, Nelson Holte M, Withers S, et al. TIEG1 modulates ?-catenin sub-cellular localization and enhances Wnt signaling in bone. Nucleic Acids Res. 2017;45:5170-5182 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 6a
- western blot; human; loading ...; fig 6b
| Barnes L, Saurat J, Kaya G. Senescent Atrophic Epidermis Retains Lrig1+ Stem Cells and Loses Wnt Signaling, a Phenotype Shared with CD44KO Mice. PLoS ONE. 2017;12:e0169452 pubmed publisher |
- immunohistochemistry; mouse; 1:250; loading ...; tbl 1
| Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig s7d
| Lian G, Dettenhofer M, Lu J, Downing M, Chenn A, Wong T, et al. Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development. 2016;143:4509-4520 pubmed |
| Guo Y, Wang L, Li B, Xu H, Yang J, Zheng L, et al. Wnt/?-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling. Oncotarget. 2016;7:42513-42526 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:400; fig 6e
| Petit F, Deng C, Jamin S. Partial Müllerian Duct Retention in Smad4 Conditional Mutant Male Mice. Int J Biol Sci. 2016;12:667-76 pubmed publisher |
- western blot; mouse; loading ...; fig 6a
| Lu C, Thoeni C, Connor A, Kawabe H, Gallinger S, Rotin D. Intestinal knockout of Nedd4 enhances growth of Apcmin tumors. Oncogene. 2016;35:5839-5849 pubmed publisher |
- western blot; human; fig 2
| Kim J, Lee H, Park K, Choi Y, Nam J, Hong I. CWP232228 targets liver cancer stem cells through Wnt/β-catenin signaling: a novel therapeutic approach for liver cancer treatment. Oncotarget. 2016;7:20395-409 pubmed publisher |
- immunohistochemistry; mouse; 1:100; fig 4d
| Franco C, Jones M, Bernabeu M, Vion A, Barbacena P, Fan J, et al. Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling. elife. 2016;5:e07727 pubmed publisher |
- immunocytochemistry; mouse
| Yuri S, Nishikawa M, Yanagawa N, Jo O, Yanagawa N. Maintenance of Mouse Nephron Progenitor Cells in Aggregates with Gamma-Secretase Inhibitor. PLoS ONE. 2015;10:e0129242 pubmed publisher |
- immunocytochemistry; mouse; 1:100; fig s3d
| Yang N, Li L, Eguether T, Sundberg J, Pazour G, Chen J. Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis. Development. 2015;142:2194-202 pubmed publisher |
- western blot; human; fig 3b
| Beltran M, Aparicio Prat E, Mazzolini R, Millanes Romero A, Massó P, Jenner R, et al. Splicing of a non-coding antisense transcript controls LEF1 gene expression. Nucleic Acids Res. 2015;43:5785-97 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:500; fig 6n-s
| Gay M, Valenta T, Herr P, Paratore Hari L, Basler K, Sommer L. Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation. BMC Biol. 2015;13:24 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:300; fig 1
| Cui C, Yin M, Sima J, Childress V, Michel M, Piao Y, et al. Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014;141:3752-60 pubmed publisher |
- chromatin immunoprecipitation; mouse
| Landin Malt A, Cesario J, Tang Z, Brown S, Jeong J. Identification of a face enhancer reveals direct regulation of LIM homeobox 8 (Lhx8) by wingless-int (WNT)/β-catenin signaling. J Biol Chem. 2014;289:30289-301 pubmed publisher |
- western blot; human; fig 5
| Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, et al. YAP/TAZ incorporation in the ?-catenin destruction complex orchestrates the Wnt response. Cell. 2014;158:157-70 pubmed publisher |
- western blot; human; fig 4
| Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, et al. Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. Carcinogenesis. 2014;35:1901-10 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Xu Y, Xu Y, Liao L, Zhou N, Theissen S, Liao X, et al. Inducible knockout of Twist1 in young and adult mice prolongs hair growth cycle and has mild effects on general health, supporting Twist1 as a preferential cancer target. Am J Pathol. 2013;183:1281-1292 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:75
| Lewis A, Vasudevan H, O Neill A, Soriano P, Bush J. The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Dev Biol. 2013;379:229-34 pubmed publisher |
- western blot; mouse; 1:1000
| Wallmen B, Schrempp M, Hecht A. Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/?-catenin target gene expression. Nucleic Acids Res. 2012;40:9455-69 pubmed publisher |
| Wu J, Tian Y, Han L, Liu C, Sun T, Li L, et al. FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling. BMC Biol. 2020;18:87 pubmed publisher |
| Alldredge A, Fuhrmann S. Loss of Axin2 Causes Ocular Defects During Mouse Eye Development. Invest Ophthalmol Vis Sci. 2016;57:5253-5262 pubmed publisher |
| Phua Y, Chu J, Marrone A, Bodnar A, Sims Lucas S, Ho J. Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival. Physiol Rep. 2015;3: pubmed publisher |
| Raines A, Magella B, Adam M, Potter S. Key pathways regulated by HoxA9,10,11/HoxD9,10,11 during limb development. BMC Dev Biol. 2015;15:28 pubmed publisher |
| Bankhead E, Colasanto M, Dyorich K, Jamrich M, Murtaugh L, Fuhrmann S. Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis. Am J Pathol. 2015;185:197-213 pubmed publisher |
| Shang D, Bi R, Han T, Wang D, Tian Y, Liu Y. Expression and proliferation-promoting role of lymphoid enhancer-binding factor 1 in human clear cell renal carcinoma. Cancer Invest. 2014;32:368-74 pubmed publisher |
| Boras Granic K, Dann P, VanHouten J, Karaplis A, Wysolmerski J. Deletion of the nuclear localization sequences and C-terminus of PTHrP impairs embryonic mammary development but also inhibits PTHrP production. PLoS ONE. 2014;9:e90418 pubmed publisher |
| Wang W, Yao Y, Jiang L, Hu T, Ma J, Ruan Z, et al. Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients. Dis Markers. 2013;35:395-405 pubmed publisher |
| Walther N, Ulrich A, Vockerodt M, von Bonin F, Klapper W, Meyer K, et al. Aberrant lymphocyte enhancer-binding factor 1 expression is characteristic for sporadic Burkitt's lymphoma. Am J Pathol. 2013;182:1092-8 pubmed publisher |
| Zhang Z, Wlodarczyk B, Niederreither K, Venugopalan S, Florez S, Finnell R, et al. Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS ONE. 2011;6:e24608 pubmed publisher |
| Luderer H, Gori F, Demay M. Lymphoid enhancer-binding factor-1 (LEF1) interacts with the DNA-binding domain of the vitamin D receptor. J Biol Chem. 2011;286:18444-51 pubmed publisher |
| Kriegl L, Horst D, Reiche J, Engel J, Kirchner T, Jung A. LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer. J Transl Med. 2010;8:123 pubmed publisher |
