Caspase-1 Antibody | Cell Signaling Technology 2225 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Caspase-1 Antibody

catalog :

2225

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; fig 3a	Okondo M, Johnson D, Sridharan R, Go E, Chui A, Wang M, et al. DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis. Nat Chem Biol. 2017;13:46-53 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 8b immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2 western blot; human; 1:1000; loading ...; fig 3a, 3c	Yang Y, Liu P, Bao W, Chen S, Wu F, Zhu P. Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. BMC Cancer. 2020;20:28 pubmed publisher
western blot; human; loading ...; fig 2b	Johnson D, Taabazuing C, Okondo M, Chui A, Rao S, Brown F, et al. DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia. Nat Med. 2018;24:1151-1156 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 1a western blot; human; loading ...; fig 1f	Tang T, Lang X, Xu C, Wang X, Gong T, Yang Y, et al. CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation. Nat Commun. 2017;8:202 pubmed publisher
immunocytochemistry; human; 1:50; fig 3 western blot; human; 1:1000; fig 2	Tseng H, Vong C, Kwan Y, Lee S, Hoi M. TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells. Sci Rep. 2016;6:35016 pubmed publisher
western blot; human; loading ...; fig 4a	Xing Y, Cao R, Hu H. TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles). Cell Death Dis. 2016;7:e2322 pubmed publisher
western blot; human; loading ...; fig 3a	Ma X, Guo P, Qiu Y, Mu K, Zhu L, Zhao W, et al. Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway. Oncotarget. 2016;7:36185-36197 pubmed publisher
	Hao M, Wang R, Wang W. Cell Therapies in Cardiomyopathy: Current Status of Clinical Trials. Anal Cell Pathol (Amst). 2017;2017:9404057 pubmed publisher
	Wu X, Zhang H, Salmani J, Fu R, Chen B. Advances of wogonin, an extract from Scutellaria baicalensis, for the treatment of multiple tumors. Onco Targets Ther. 2016;9:2935-43 pubmed publisher

product information

SKU :

2225S

Product-Name :

Caspase-1 Antibody

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

Applications :

Immunohistochemistry (Paraffin)

Product-Category :

Apoptosis

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

20 p20. 30 to 45 beta, delta, gamma. 50 alpha.

Host :

Rabbit

Target :

Casp1

Primary-Protein :

Casp1

Alt-Names :

CASP-1,CASP1,CASP1 nirs variant 1,Caspase-1,Caspase-1 subunit p10,Caspase-1 subunit p20,ICE,IL-1 beta-converting enzyme,IL-1BC,IL1B-convertase,IL1BC,IL1BCE,Interleukin-1 beta convertase,Interleukin-1 beta-converting enzyme,caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase),caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase),interleukin 1-B converting enzyme,interleukin 1-beta convertase,p45

more info or order :

Cell Signaling Technology product webpage