product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Caspase-2 (C2) Mouse mAb
catalog :
2224
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C2
reactivity :
human
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 5
Tagscherer K, Fassl A, Sinkovic T, Richter J, Schecher S, Macher Goeppinger S, et al. MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen. Cancer Cell Int. 2016;16:42 pubmed publisher
  • western blot; human; fig 3
Alsafadi S, Tourpin S, Bessoltane N, Salomé Desnoulez S, Vassal G, André F, et al. Nuclear localization of the caspase-3-cleaved form of p73 in anoikis. Oncotarget. 2016;7:12331-43 pubmed publisher
  • western blot; human; fig 4c
Harashima N, Minami T, Uemura H, Harada M. Transfection of poly(I:C) can induce reactive oxygen species-triggered apoptosis and interferon-β-mediated growth arrest in human renal cell carcinoma cells via innate adjuvant receptors and the 2-5A system. Mol Cancer. 2014;13:217 pubmed publisher
  • western blot; human; fig 4
Lamottke B, Kaiser M, Mieth M, Heider U, Gao Z, Nikolova Z, et al. The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases. Eur J Haematol. 2012;88:406-15 pubmed publisher
Tan G, Wu L, Tan J, Zhang B, Tai W, Xiong S, et al. MiR-1180 promotes apoptotic resistance to human hepatocellular carcinoma via activation of NF-κB signaling pathway. Sci Rep. 2016;6:22328 pubmed publisher
Zhang M, Harashima N, Moritani T, Huang W, Harada M. The Roles of ROS and Caspases in TRAIL-Induced Apoptosis and Necroptosis in Human Pancreatic Cancer Cells. PLoS ONE. 2015;10:e0127386 pubmed publisher
Tamaki H, Harashima N, Hiraki M, Arichi N, Nishimura N, Shiina H, et al. Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition. Oncotarget. 2014;5:11399-412 pubmed
Amaya M, Voss K, Sampey G, Senina S, de La Fuente C, Mueller C, et al. The role of IKK? in Venezuelan equine encephalitis virus infection. PLoS ONE. 2014;9:e86745 pubmed publisher
Fredericks W, Sepulveda J, Lai P, Tomaszewski J, Lin M, McGarvey T, et al. The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes. Oncotarget. 2013;4:1075-92 pubmed
Weng H, Hsu M, WANG C, Chen B, Hong C, Chen M, et al. Zerumbone suppresses IKK?, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells. J Biomed Sci. 2012;19:86 pubmed publisher
Schaefers M, Breshears L, Anderson M, Lin Y, Grill A, Panyam J, et al. Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. PLoS ONE. 2012;7:e32813 pubmed publisher
Seervi M, Joseph J, Sobhan P, Bhavya B, Santhoshkumar T. Essential requirement of cytochrome c release for caspase activation by procaspase-activating compound defined by cellular models. Cell Death Dis. 2011;2:e207 pubmed publisher
Chen R, Ryzhakov G, Cooray S, Randow F, Smith G. Inhibition of IkappaB kinase by vaccinia virus virulence factor B14. PLoS Pathog. 2008;4:e22 pubmed publisher
product information
SKU :
2224S
Product-Name :
Caspase-2 (C2) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Western blot
Product-Category :
Apoptosis
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
12, 14, 48
Host :
Mouse
Target :
Casp2
Primary-Protein :
Casp2
Alt-Names :
CASP-2,CASP2,Caspase-2,Caspase-2 subunit p12,Caspase-2 subunit p13,Caspase-2 subunit p18,ICH-1 protease,ICH-1L,ICH-1L/1S,ICH1,NEDD-2,NEDD2,NEDD2 apoptosis regulatory,Neural precursor cell expressed developmentally down-regulated protein 2,Protease ICH-1,caspase 2, apoptosis-related cysteine peptidase,neural precursor cell expressed, developmentally down-regulated 2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.