product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Glut4 (1F8) Mouse mAb
catalog :
2213
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1F8
reactivity :
human, mouse, rat, pig
application :
western blot
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; pig; loading ...; fig 5b
Cai C, Qian L, Jiang S, Sun Y, Wang Q, Ma D, et al. Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs. Oncotarget. 2017;8:34911-34922 pubmed publisher
  • western blot; mouse; loading ...; fig 3b
Doğan A, Demirci S, Apdik H, Bayrak O, Gulluoglu S, Tuysuz E, et al. A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway. Metabolism. 2017;69:130-142 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2c
Major J, Dewan A, Salih M, Leddy J, Tuana B. E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy. PLoS ONE. 2017;12:e0170066 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7a
Yu N, Fang X, Zhao D, Mu Q, Zuo J, Ma Y, et al. Anti-Diabetic Effects of Jiang Tang Xiao Ke Granule via PI3K/Akt Signalling Pathway in Type 2 Diabetes KKAy Mice. PLoS ONE. 2017;12:e0168980 pubmed publisher
  • western blot; mouse; loading ...; fig 4d
Kocsis T, Trencsenyi G, Szabó K, Baán J, Müller G, Mendler L, et al. Myostatin propeptide mutation of the hypermuscular Compact mice decreases the formation of myostatin and improves insulin sensitivity. Am J Physiol Endocrinol Metab. 2017;312:E150-E160 pubmed publisher
  • western blot; mouse; loading ...; fig 6c
Charrier A, Wang L, Stephenson E, Ghanta S, Ko C, Croniger C, et al. Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice. Am J Physiol Endocrinol Metab. 2016;311:E869-E880 pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Harfmann B, Schroder E, Kachman M, Hodge B, Zhang X, Esser K. Muscle-specific loss of Bmal1 leads to disrupted tissue glucose metabolism and systemic glucose homeostasis. Skelet Muscle. 2016;6:12 pubmed publisher
  • western blot; mouse; 1:25,000; loading ...; fig 1d
Vazirani R, Verma A, Sadacca L, Buckman M, Picatoste B, Beg M, et al. Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance. Diabetes. 2016;65:1577-89 pubmed publisher
  • western blot; mouse; fig 1
Pinel A, Rigaudière J, Laillet B, Pouyet C, Malpuech Brugère C, Prip Buus C, et al. N-3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells. Biochim Biophys Acta. 2016;1861:12-20 pubmed publisher
  • western blot; mouse; loading ...; fig 3e
Buchner D, Charrier A, Srinivasan E, Wang L, Paulsen M, Ljungman M, et al. Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA. J Biol Chem. 2015;290:6376-86 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, et al. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxid Redox Signal. 2015;22:819-31 pubmed publisher
  • western blot; mouse
Ost M, Werner F, Dokas J, Klaus S, Voigt A. Activation of AMPK?2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS ONE. 2014;9:e94689 pubmed publisher
Ismail M, Mateos L, Maioli S, Merino Serrais P, Ali Z, Lodeiro M, et al. 27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation. J Exp Med. 2017;214:699-717 pubmed publisher
Otsuka K, Suzuki K. Differences in Radiation Dose Response between Small and Large Intestinal Crypts. Radiat Res. 2016;186:302-14 pubmed publisher
Beaton N, Rudigier C, Moest H, Müller S, Mrosek N, Röder E, et al. TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling. Mol Metab. 2015;4:795-810 pubmed publisher
Christoffolete M, Silva W, Ramos G, Bento M, Costa M, Ribeiro M, et al. Muscle IGF-1-induced skeletal muscle hypertrophy evokes higher insulin sensitivity and carbohydrate use as preferential energy substrate. Biomed Res Int. 2015;2015:282984 pubmed publisher
Ramratnam M, Sharma R, D Auria S, Lee S, Wang D, Huang X, et al. Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice. J Am Heart Assoc. 2014;3: pubmed publisher
Myers S, Nield A, Chew G, Myers M. The zinc transporter, Slc39a7 (Zip7) is implicated in glycaemic control in skeletal muscle cells. PLoS ONE. 2013;8:e79316 pubmed publisher
Liu Q, Zhu X, Xu L, Fu Y, Garvey W. 6-Mercaptopurine augments glucose transport activity in skeletal muscle cells in part via a mechanism dependent upon orphan nuclear receptor NR4A3. Am J Physiol Endocrinol Metab. 2013;305:E1081-92 pubmed publisher
Linz D, Hohl M, Mahfoud F, Reil J, Linz W, Hübschle T, et al. Cardiac remodeling and myocardial dysfunction in obese spontaneously hypertensive rats. J Transl Med. 2012;10:187 pubmed publisher
product information
SKU :
2213S
Product-Name :
Glut4 (1F8) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
50
Host :
Mouse
Target :
Glut4
Primary-Protein :
GLUT4
Alt-Names :
GLUT-4,GLUT4,GTR4,Glucose transporter type 4, insulin-responsive,SLC2A4,Solute carrier family 2, facilitated glucose transporter member 4,insulin-responsive glucose transporter type 4,solute carrier family 2 (facilitated glucose transporter), member 4
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.