product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Caspase-12 Antibody
catalog :
2202
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry - frozen section
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 4g
Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  • western blot; mouse; loading ...; fig 4a
Tamura Y, Matsunaga Y, Kitaoka Y, Hatta H. Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2017;72:299-308 pubmed publisher
  • western blot; human; loading ...; fig 4a
Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher
  • western blot; human; 1:1000; fig 1
Anta B, Pérez Rodríguez A, Castro J, García Domínguez C, Ibiza S, Martínez N, et al. PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. Cell Death Dis. 2016;7:e2311 pubmed publisher
  • western blot; mouse
Wolter S, Kloth C, Golombek M, Dittmar F, Försterling L, Seifert R. cCMP causes caspase-dependent apoptosis in mouse lymphoma cell lines. Biochem Pharmacol. 2015;98:119-31 pubmed publisher
  • western blot; mouse; fig 4
Lauretti E, Praticò D. Glucose deprivation increases tau phosphorylation via P38 mitogen-activated protein kinase. Aging Cell. 2015;14:1067-74 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5
Sarkar C, Zhao Z, Aungst S, Sabirzhanov B, Faden A, Lipinski M. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy. 2014;10:2208-22 pubmed publisher
  • western blot; human; fig 2
Lin Y, Zhang H, Liang J, Li K, Zhu W, Fu L, et al. Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers. Proc Natl Acad Sci U S A. 2014;111:E4504-12 pubmed publisher
Li K, Liang J, Lin Y, Zhang H, Xiao X, Tan Y, et al. A classical PKA inhibitor increases the oncolytic effect of M1 virus via activation of exchange protein directly activated by cAMP 1. Oncotarget. 2016;7:48443-48455 pubmed publisher
Mancini M, Lien E, Toker A. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis. Oncotarget. 2016;7:17301-13 pubmed publisher
Yin P, Xu J, He S, Liu F, Yin J, Wan C, et al. Endoplasmic Reticulum Stress in Heat- and Shake-Induced Injury in the Rat Small Intestine. PLoS ONE. 2015;10:e0143922 pubmed publisher
Pantazi E, Folch Puy E, Bejaoui M, Panisello A, Varela A, Rolo A, et al. PPARα Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury. Biomed Res Int. 2015;2015:894679 pubmed publisher
Zhang C, Jiang Y, Zhang J, Huang J, Wang J. 8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells. Int J Mol Sci. 2015;16:14979-96 pubmed publisher
Liu S, Sarkar C, Dinizo M, Faden A, Koh E, Lipinski M, et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 2015;6:e1582 pubmed publisher
Omi T, Tanimukai H, Kanayama D, Sakagami Y, Tagami S, Okochi M, et al. Fluvoxamine alleviates ER stress via induction of Sigma-1 receptor. Cell Death Dis. 2014;5:e1332 pubmed publisher
Luo M, Yang F, Leu N, Landaiche J, Handel M, Benavente R, et al. MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination. Nat Commun. 2013;4:2788 pubmed publisher
Pan H, Yang C, Hung Y, Lee W, Tien H, Shen C, et al. Reciprocal modulation of C/EBP-? and C/EBP-? by IL-13 in activated microglia prevents neuronal death. Eur J Immunol. 2013;43:2854-65 pubmed publisher
Brennan G, Jimenez Mateos E, McKiernan R, Engel T, Tzivion G, Henshall D. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS ONE. 2013;8:e54491 pubmed publisher
Muaddi H, Majumder M, Peidis P, Papadakis A, Holcik M, Scheuner D, et al. Phosphorylation of eIF2? at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency. Mol Biol Cell. 2010;21:3220-31 pubmed publisher
Kerbiriou M, Teng L, Benz N, Trouvé P, Ferec C. The calpain, caspase 12, caspase 3 cascade leading to apoptosis is altered in F508del-CFTR expressing cells. PLoS ONE. 2009;4:e8436 pubmed publisher
product information
SKU :
2202P
Product-Name :
Caspase-12 Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
M
Applications :
Western blot
Product-Category :
Apoptosis
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
42, 55
Host :
Rabbit
Target :
Casp12 (Lys158, SS) cleaved
Primary-Protein :
Casp12
Alt-Names :
CASP-12,CASPC,Casp12,Caspase-12,caspase 12
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.