Phospho-Chk2 (Thr68) (C13C1) Rabbit mAb | Cell Signaling Technology 2197S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-Chk2 (Thr68) (C13C1) Rabbit mAb

catalog :

2197S

quantity :

100 ul

price :

274 USD

clonality :

monoclonal

host :

rabbit

antigen modification :

phosphorylated

reactivity :

African green monkey, human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Cell Signaling Technology product webpage

citations: 12

Published Application/Species/Dilution	Reference
western blot; human; fig 5	Kralovicova J, Knut M, Cross N, Vorechovsky I. Exon-centric regulation of ATM expression is population-dependent and amenable to antisense modification by pseudoexon targeting. Sci Rep. 2016;6:18741 pubmed publisher
western blot; human; fig 7	Köhler C, Koalick D, Fabricius A, Parplys A, Borgmann K, Pospiech H, et al. Cdc45 is limiting for replication initiation in humans. Cell Cycle. 2016;15:974-85 pubmed publisher
western blot; human; fig s4	Huhn D, Kousholt A, Sørensen C, Sartori A. miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP. Oncogene. 2015;34:3977-84 pubmed publisher
western blot; human; 1:1000; fig s2	Fernandez-Vidal A, Guitton-Sert L, Cadoret J, Drac M, Schwob E, Baldacci G, et al. A role for DNA polymerase θ in the timing of DNA replication. Nat Commun. 2014;5:4285 pubmed publisher
western blot; African green monkey	Kim S, Lee S, Lee S, Park J, Ryu D. Arsenite-induced changes in hepatic protein abundance in cynomolgus monkeys (Macaca fascicularis). Proteomics. 2014;14:1833-43 pubmed publisher
immunocytochemistry; human; 1:50 western blot; human; 1:1000	Nikitin P, Price A, McFadden K, Yan C, Luftig M. Mitogen-induced B-cell proliferation activates Chk2-dependent G1/S cell cycle arrest. PLoS ONE. 2014;9:e87299 pubmed publisher
western blot; human	Sims J, Wade P. Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin. Mol Biol Cell. 2011;22:3094-102 pubmed publisher
	Oike T, Komachi M, Ogiwara H, Amornwichet N, Saitoh Y, Torikai K, et al. C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe. Radiother Oncol. 2014;111:222-7 pubmed publisher
	Tu W, Li B, Huang B, Wang Y, Liu X, Guan H, et al. γH2AX foci formation in the absence of DNA damage: mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway. FEBS Lett. 2013;587:3437-43 pubmed publisher
	Li B, Shang Z, Yin J, Xu Q, Liu X, Wang Y, et al. PIG3 functions in DNA damage response through regulating DNA-PKcs homeostasis. Int J Biol Sci. 2013;9:425-34 pubmed publisher
	Oike T, Ogiwara H, Torikai K, Nakano T, Yokota J, Kohno T. Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining. Int J Radiat Oncol Biol Phys. 2012;84:815-21 pubmed publisher
	Zhu H, Yue J, Pan Z, Wu H, Cheng Y, Lu H, et al. Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining. PLoS ONE. 2010;5:e12055 pubmed publisher

product information

SKU :

2197S

Product-Name :

Phospho-Chk2 (Thr68) (C13C1) Rabbit mAb

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, (Mk)

Applications :

Flow cytometry

Product-Category :

Cell Cycle / Checkpoint Control

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

Chk2 (Thr68) phosphate

Primary-Protein :

Chk2

Alt-Names :

CHEK2,CHK2,CHK2 checkpoint homolog (S. pombe),Cds1,HuCds1,LFS2,PP1425,RAD53,Serine/threonine-protein kinase Chk2,checkpoint-like protein CHK2,protein kinase CHK2

more info or order :

Cell Signaling Technology product webpage