product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SRC-1 (128E7) Rabbit mAb
catalog :
2191S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 12
Published Application/Species/DilutionReference
  • western blot (knockout validation); human; fig 4
  • immunocytochemistry; human; fig 4
Liu X, Li H, Rajurkar M, Li Q, Cotton J, Ou J, et al. Tead and AP1 Coordinate Transcription and Motility. Cell Rep. 2016;14:1169-80 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 1
  • western blot (knockout validation); mouse; fig 5
Chen X, Qin L, Liu Z, Liao L, Martin J, Xu J. Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015;11:1056-72 pubmed publisher
  • western blot; rat; fig 3
Whitaker A, Farooq M, Edwards S, Gilpin N. Post-traumatic stress avoidance is attenuated by corticosterone and associated with brain levels of steroid receptor co-activator-1 in rats. Stress. 2016;19:69-77 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Dai L, Endo D, Akiyama N, Yamamoto-Fukuda T, Koji T. Aberrant levels of histone H3 acetylation induce spermatid anomaly in mouse testis. Histochem Cell Biol. 2015;143:209-24 pubmed publisher
  • immunohistochemistry - paraffin section; human
Xu Y, Hu B, Qin L, Zhao L, Wang Q, Wang Q, et al. SRC-1 and Twist1 expression positively correlates with a poor prognosis in human breast cancer. Int J Biol Sci. 2014;10:396-403 pubmed publisher
  • western blot; human; 1:500
Valtcheva N, Primorac A, Jurisic G, Hollmen M, Detmar M. The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42. J Biol Chem. 2013;288:35736-48 pubmed publisher
  • western blot; human
Wagner M, Koslowski M, Paret C, Schmidt M, Tureci O, Sahin U. NCOA3 is a selective co-activator of estrogen receptor α-mediated transactivation of PLAC1 in MCF-7 breast cancer cells. BMC Cancer. 2013;13:570 pubmed publisher
  • western blot; human; 1:2500
Valdez B, Nieto Y, Murray D, Li Y, Wang G, Champlin R, et al. Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. Exp Hematol. 2012;40:800-10 pubmed publisher
Milesi M, Alarcón R, Ramos J, Muñoz-de-Toro M, Luque E, Varayoud J. Neonatal exposure to low doses of endosulfan induces implantation failure and disrupts uterine functional differentiation at the pre-implantation period in rats. Mol Cell Endocrinol. 2015;401:248-59 pubmed publisher
Vella K, Ramadoss P, Costa-e-Sousa R, Astapova I, Ye F, Holtz K, et al. Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors. Mol Cell Biol. 2014;34:1564-75 pubmed publisher
Wu J, Liu J, Jia R, Song H. Nur77 inhibits androgen-induced bladder cancer growth. Cancer Invest. 2013;31:654-60 pubmed publisher
Jennings C, O'Grady A, Cummins R, Murer B, Al-Alawi M, Madden S, et al. Sustained expression of steroid receptor coactivator SRC-2/TIF-2 is associated with better prognosis in malignant pleural mesothelioma. J Thorac Oncol. 2012;7:243-8 pubmed publisher
product information
SKU :
2191S
Product-Name :
SRC-1 (128E7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
180
Host :
Rabbit
Target :
SRC-1
Primary-Protein :
SRC-1
Alt-Names :
BHLHE74,Class E basic helix-loop-helix protein 74,F-SRC-1,Hin-2 protein,KAT13A,MGC129719,MGC129720,NCOA1,NCoA-1,Nuclear receptor coactivator 1,PAX3/NCOA1 fusion protein,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,SRC-1,SRC1,Steroid receptor coactivator 1,bHLHe42,steroid receptor coactivator-1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.