SRC-1 (128E7) Rabbit mAb | Cell Signaling Technology 2191 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

SRC-1 (128E7) Rabbit mAb

catalog :

2191

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

128E7

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; fig 4 immunocytochemistry; human; fig 4	Liu X, Li H, Rajurkar M, Li Q, Cotton J, Ou J, et al. Tead and AP1 Coordinate Transcription and Motility. Cell Rep. 2016;14:1169-1180 pubmed publisher
western blot knockout validation; mouse; fig 1 immunohistochemistry - paraffin section; mouse; fig 1	Chen X, Qin L, Liu Z, Liao L, Martin J, Xu J. Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015;11:1056-72 pubmed publisher
western blot; human; 1:1000; loading ...; fig 7a immunoprecipitation; mouse; 1:1000; loading ...; fig 7b	He Z, Zhang J, Huang Z, Du Q, Li N, Zhang Q, et al. Sumoylation of RORγt regulates TH17 differentiation and thymocyte development. Nat Commun. 2018;9:4870 pubmed publisher
western blot; rat; fig 3	Whitaker A, Farooq M, Edwards S, Gilpin N. Post-traumatic stress avoidance is attenuated by corticosterone and associated with brain levels of steroid receptor co-activator-1 in rats. Stress. 2016;19:69-77 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100	Dai L, Endo D, Akiyama N, Yamamoto Fukuda T, Koji T. Aberrant levels of histone H3 acetylation induce spermatid anomaly in mouse testis. Histochem Cell Biol. 2015;143:209-24 pubmed publisher
immunohistochemistry - paraffin section; human	Xu Y, Hu B, Qin L, Zhao L, Wang Q, Wang Q, et al. SRC-1 and Twist1 expression positively correlates with a poor prognosis in human breast cancer. Int J Biol Sci. 2014;10:396-403 pubmed publisher
chromatin immunoprecipitation; mouse western blot; mouse	Vella K, Ramadoss P, Costa e Sousa R, Astapova I, Ye F, Holtz K, et al. Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors. Mol Cell Biol. 2014;34:1564-75 pubmed publisher
western blot; human	Wagner M, Koslowski M, Paret C, Schmidt M, Tureci O, Sahin U. NCOA3 is a selective co-activator of estrogen receptor ?-mediated transactivation of PLAC1 in MCF-7 breast cancer cells. BMC Cancer. 2013;13:570 pubmed publisher
western blot; human; 1:500	Valtcheva N, Primorac A, Jurisic G, Hollmen M, Detmar M. The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42. J Biol Chem. 2013;288:35736-48 pubmed publisher
western blot; human; 1:2500	Valdez B, Nieto Y, Murray D, Li Y, Wang G, Champlin R, et al. Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. Exp Hematol. 2012;40:800-10 pubmed publisher
	Hinton A, Yang Y, Quick A, Xu P, Reddy C, Yan X, et al. SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice. PLoS ONE. 2016;11:e0168644 pubmed publisher
	Milesi M, AlarcÃ³n R, Ramos J, MuÃ±oz de Toro M, Luque E, Varayoud J. Neonatal exposure to low doses of endosulfan induces implantation failure and disrupts uterine functional differentiation at the pre-implantation period in rats. Mol Cell Endocrinol. 2015;401:248-59 pubmed publisher
	Wu J, Liu J, Jia R, Song H. Nur77 inhibits androgen-induced bladder cancer growth. Cancer Invest. 2013;31:654-60 pubmed publisher
	Jennings C, O Grady A, Cummins R, Murer B, Al Alawi M, Madden S, et al. Sustained expression of steroid receptor coactivator SRC-2/TIF-2 is associated with better prognosis in malignant pleural mesothelioma. J Thorac Oncol. 2012;7:243-8 pubmed publisher

product information

SKU :

2191S

Product-Name :

SRC-1 (128E7) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunohistochemistry (Paraffin)

Product-Category :

Chromatin Regulation / Nuclear Function

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

180

Host :

Rabbit

Target :

SRC-1

Primary-Protein :

SRC-1

Alt-Names :

BHLHE74,Class E basic helix-loop-helix protein 74,F-SRC-1,Hin-2 protein,KAT13A,MGC129719,MGC129720,NCOA1,NCoA-1,Nuclear receptor coactivator 1,PAX3/NCOA1 fusion protein,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,SRC-1,SRC1,Steroid receptor coactivator 1,bHLHe42,steroid receptor coactivator-1

more info or order :

Cell Signaling Technology product webpage