product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PGC-1α (3G6) Rabbit mAb
catalog :
2178
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
3G6
reactivity :
human, mouse
application :
western blot, flow cytometry
citations: 10
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1d
Callender L, Carroll E, Bober E, Akbar A, Solito E, Henson S. Mitochondrial mass governs the extent of human T cell senescence. Aging Cell. 2020;19:e13067 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 2a
Viana Huete V, Guillen C, García G, Fernandez S, García Aguilar A, Kahn C, et al. Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity. Endocrinology. 2018;159:323-340 pubmed publisher
  • western blot; mouse; 1:1000
Safdar A, Khrapko K, Flynn J, Saleem A, De Lisio M, Johnston A, et al. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle. 2016;6:7 pubmed publisher
  • western blot; mouse; 1:1000; tbl 1
Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  • western blot; mouse; fig 4
Ge W, Yuan M, Ceylan A, Wang X, Ren J. Mitochondrial aldehyde dehydrogenase protects against doxorubicin cardiotoxicity through a transient receptor potential channel vanilloid 1-mediated mechanism. Biochim Biophys Acta. 2016;1862:622-634 pubmed publisher
  • western blot; mouse; 1:500; fig 5
Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, et al. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxid Redox Signal. 2015;22:819-31 pubmed publisher
Li R, Jia Y, Pan S, Li X, Song H, Zhao R. Glucocorticoid Receptor Mediates the Effect of High-Fat Diet on Mitochondrial Oxidative Phosphorylation in Mouse Liver. DNA Cell Biol. 2016;35:51-8 pubmed publisher
Felder T, Soyal S, Oberkofler H, Hahne P, Auer S, Weiss R, et al. Characterization of novel peroxisome proliferator-activated receptor ? coactivator-1? (PGC-1?) isoform in human liver. J Biol Chem. 2011;286:42923-36 pubmed publisher
Alavian K, Li H, Collis L, Bonanni L, Zeng L, Sacchetti S, et al. Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase. Nat Cell Biol. 2011;13:1224-33 pubmed publisher
Safdar A, Hamadeh M, Kaczor J, Raha S, DeBeer J, Tarnopolsky M. Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults. PLoS ONE. 2010;5:e10778 pubmed publisher
product information
SKU :
2178S
Product-Name :
PGC-1α (3G6) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Western blot
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
130
Host :
Rabbit
Target :
PGC-1 alpha
Primary-Protein :
PGC-1 alpha
Alt-Names :
LEM6,Ligand effect modulator 6,PGC-1(alpha),PGC-1-alpha,PGC-1v,PGC1,PGC1A,PPAR gamma coactivator variant form,PPAR gamma coactivator-1,PPAR-gamma coactivator 1-alpha,PPARGC-1-alpha,PPARGC1,PPARGC1A,PRGC1,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,ligand effect modulator-6,peroxisome proliferative activated receptor, gamma, coactivator 1, alpha,peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.