product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HER2/ErbB2 (29D8) Rabbit mAb
catalog :
2165
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
29D8
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, western blot knockout validation
citations: 91
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:200; fig 1a
Chen Y, Wang R, Huang S, Henson E, Bi J, Gibson S. Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b, s4c
  • western blot; mouse; 1:1000; loading ...; fig 3a
Goyette M, Elkholi I, Apcher C, Kuasne H, Rothlin C, Muller W, et al. Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1g
Prokakis E, Dyas A, Grün R, Fritzsche S, Bedi U, Kazerouni Z, et al. USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response. Oncogene. 2021;40:4004-4018 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 2c
Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, et al. DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells. Theranostics. 2021;11:6355-6369 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s2a
  • western blot; mouse; loading ...; fig s2b
Yang Y, Leonard M, Luo Z, Yeo S, Bick G, Hao M, et al. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell Rep. 2021;34:108822 pubmed publisher
  • western blot; human; loading ...; fig 1b, 2b
Liu Q, Borcherding N, Shao P, Maina P, Zhang W, Qi H. Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance. EBioMedicine. 2020;51:102612 pubmed publisher
  • western blot; human; loading ...; fig 1a
Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher
  • western blot; human; loading ...; fig s3b
Zhao H, Martin E, Matalkah F, Shah N, Ivanov A, Ruppert J, et al. Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis. Oncogene. 2019;38:2275-2290 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1g
Schumacher M, Hedl M, Abraham C, Bernard J, Lozano P, Hsieh J, et al. ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation. Cell Death Dis. 2017;8:e2622 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3
Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, et al. Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines. J Cancer Res Clin Oncol. 2017;143:573-600 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4g
Mitra S, Ghosh B, Gayen N, Roy J, Mandal A. Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation. J Biol Chem. 2016;291:24579-24593 pubmed
  • flow cytometry; human; loading ...; fig 1a
  • immunocytochemistry; human
  • immunohistochemistry; human
Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed publisher
  • western blot; human; loading ...; fig 2a
LAW M, Ferreira R, Davis B, Higgins P, Kim J, Castellano R, et al. CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment. Breast Cancer Res. 2016;18:80 pubmed publisher
  • immunoprecipitation; human; loading ...; fig s8
Szymanska M, Fosdahl A, Nikolaysen F, Pedersen M, Grandal M, Stang E, et al. A combination of two antibodies recognizing non-overlapping epitopes of HER2 induces kinase activity-dependent internalization of HER2. J Cell Mol Med. 2016;20:1999-2011 pubmed publisher
  • western blot; human; loading ...; fig 1a
Saisana M, Griffin S, May F. Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation. Oncotarget. 2016;7:54445-54462 pubmed publisher
  • western blot; human; 1:500; fig 2
Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel Studer I, Meyer Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed publisher
  • western blot; human; fig 1b
Stindt S, Cebula P, Albrecht U, Keitel V, Schulte Am Esch J, Knoefel W, et al. Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family. PLoS ONE. 2016;11:e0148711 pubmed publisher
  • western blot; human; fig 1
Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed publisher
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 2
Khalil H, Langdon S, Kankia I, Bown J, Deeni Y. NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies. Oxid Med Cell Longev. 2016;2016:4148791 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 2b
Yamaguchi T, Lu C, Ida L, Yanagisawa K, Usukura J, Cheng J, et al. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. Nat Commun. 2016;7:10060 pubmed publisher
  • western blot; human; 1:1000; fig 7e
Askoxylakis V, Ferraro G, Kodack D, Badeaux M, Shankaraiah R, Seano G, et al. Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. J Natl Cancer Inst. 2016;108: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5C; S6B
Pai P, Rachagani S, Lakshmanan I, Macha M, Sheinin Y, Smith L, et al. The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Mol Oncol. 2016;10:224-39 pubmed publisher
  • immunocytochemistry; human; fig 4
Rodríguez C, Reidel S, Bal de Kier Joffé E, Jasnis M, Fiszman G. Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids. PLoS ONE. 2015;10:e0137920 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1f
Wang D, Pang Z, Clarke G, Nofech Mozes S, Liu K, Cheung A, et al. Ki-67 Membranous Staining: Biologically Relevant or an Artifact of Multiplexed Immunofluorescent Staining. Appl Immunohistochem Mol Morphol. 2016;24:447-52 pubmed publisher
  • western blot; human; fig 4
Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
  • immunohistochemistry - paraffin section; human; 1:25
Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
  • western blot; human; 1:100
Hofmann B, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, et al. COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer. Mol Cancer. 2015;14:109 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5b
Deleyrolle L, Sabourin J, Rothhut B, Fujita H, Guichet P, Teigell M, et al. OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor. PLoS ONE. 2015;10:e0122337 pubmed publisher
  • western blot; human; loading ...; fig 4f, 4g, 4h
Ferreira R, Law M, Jahn S, Davis B, Heldermon C, Reinhard M, et al. Novel agents that downregulate EGFR, HER2, and HER3 in parallel. Oncotarget. 2015;6:10445-59 pubmed
  • western blot; human
Yoo J, Kim T, Kong S, Lee J, Choi W, Kim K, et al. Role of Mig-6 in hepatic glucose metabolism. J Diabetes. 2016;8:86-97 pubmed publisher
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 1
Blanchard Z, Paul B, Craft B, ElShamy W. BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers. Breast Cancer Res. 2015;17:5 pubmed publisher
  • western blot; human; fig s1
Kumar S, Das S, Rachagani S, Kaur S, Joshi S, Johansson S, et al. NCOA3-mediated upregulation of mucin expression via transcriptional and post-translational changes during the development of pancreatic cancer. Oncogene. 2015;34:4879-89 pubmed publisher
  • western blot; human
Hong Y, Kim J, Pectasides E, Fox C, Hong S, Ma Q, et al. Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models. PLoS ONE. 2014;9:e109440 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Asp N, Pust S, Sandvig K. Flotillin depletion affects ErbB protein levels in different human breast cancer cells. Biochim Biophys Acta. 2014;1843:1987-96 pubmed publisher
  • western blot; human; loading ...; fig 1a
Xia Q, Cai Y, Peng R, Wu G, Shi Y, Jiang W. The CDK1 inhibitor RO3306 improves the response of BRCA-pro?cient breast cancer cells to PARP inhibition. Int J Oncol. 2014;44:735-44 pubmed publisher
  • western blot; dogs; loading ...; fig 1b
Linch M, Sanz Garcia M, Rosse C, Riou P, Peel N, Madsen C, et al. Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. Carcinogenesis. 2014;35:396-406 pubmed publisher
  • western blot; human; fig 2
Brouxhon S, Kyrkanides S, Teng X, O Banion M, Clarke R, Byers S, et al. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014;53:893-906 pubmed publisher
  • immunocytochemistry; mouse; 1:200
  • western blot; mouse; 1:1000
Harmelink C, Peng Y, Debenedittis P, Chen H, Shou W, Jiao K. Myocardial Mycn is essential for mouse ventricular wall morphogenesis. Dev Biol. 2013;373:53-63 pubmed publisher
  • immunocytochemistry; human; 1:150
Lindberg K, Helguero L, Omoto Y, Gustafsson J, Haldosén L. Estrogen receptor ? represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity. Breast Cancer Res. 2011;13:R43 pubmed publisher
Carter E, Gopsill J, Gomm J, Jones J, Grose R. A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer. Breast Cancer Res. 2017;19:50 pubmed publisher
Ke Y, Han Y, Guo X, Wen J, Wang K, Jiang X, et al. PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR. Nat Commun. 2017;8:14632 pubmed publisher
Mehta M, Basalingappa K, Griffith J, ANDRADE D, Babu A, Amreddy N, et al. HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy. Oncotarget. 2016;7:64820-64835 pubmed publisher
Aghajanian H, Cho Y, Manderfield L, Herling M, Gupta M, Ho V, et al. Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor. Nat Commun. 2016;7:12038 pubmed publisher
Wu T, Shi J, Geng S, Zhou W, Shi Y, Su X. The MK2/HuR signaling pathway regulates TNF-?-induced ICAM-1 expression by promoting the stabilization of ICAM-1 mRNA. BMC Pulm Med. 2016;16:84 pubmed publisher
Nunes J, Zhang H, Angelopoulos N, Chhetri J, Osipo C, Grothey A, et al. ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation. Oncotarget. 2016;7:27599-612 pubmed publisher
Papadakis E, Barker C, Syed H, Reeves T, Schwaiger S, Stuppner H, et al. The Bag-1 inhibitor, Thio-2, reverses an atypical 3D morphology driven by Bag-1L overexpression in a MCF-10A model of ductal carcinoma in situ. Oncogenesis. 2016;5:e215 pubmed publisher
Yan Q, Lou G, Qian Y, Qin B, Xu X, Wang Y, et al. SPAG9 is involved in hepatocarcinoma cell migration and invasion via modulation of ELK1 expression. Onco Targets Ther. 2016;9:1067-75 pubmed publisher
Asp N, Kvalvaag A, Sandvig K, Pust S. Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins. Oncotarget. 2016;7:25443-60 pubmed publisher
Ge J, Chang N, Zhao Z, Tian L, Duan X, Yang L, et al. Essential Roles of RNA-binding Protein HuR in Activation of Hepatic Stellate Cells Induced by Transforming Growth Factor-β1. Sci Rep. 2016;6:22141 pubmed publisher
Oh D, Kim S, Choi Y, Cho Y, Oh E, Choi J, et al. HER2 as a novel therapeutic target for cervical cancer. Oncotarget. 2015;6:36219-30 pubmed publisher
Shen Z, Malter J. Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1. Biomolecules. 2015;5:412-34 pubmed publisher
Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed publisher
Corkery D, Le Page C, Meunier L, Provencher D, Mes Masson A, Dellaire G. PRP4K is a HER2-regulated modifier of taxane sensitivity. Cell Cycle. 2015;14:1059-69 pubmed publisher
Jilg C, Ketscher A, Metzger E, Hummel B, Willmann D, Rüsseler V, et al. PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells. Oncotarget. 2014;5:12646-64 pubmed
Zhang B, Liu B, Zhang H, Wang J. Erythrocyte stiffness during morphological remodeling induced by carbon ion radiation. PLoS ONE. 2014;9:e112624 pubmed publisher
Yi P, Chew L, Zhang Z, Ren H, Wang F, Cong X, et al. KIF5B transports BNIP-2 to regulate p38 mitogen-activated protein kinase activation and myoblast differentiation. Mol Biol Cell. 2015;26:29-42 pubmed publisher
Tin A, Park A, Sundar S, Firestone G. Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells. BMC Biol. 2014;12:72 pubmed publisher
Teichert I, Steffens E, Schnaß N, Fränzel B, Krisp C, Wolters D, et al. PRO40 is a scaffold protein of the cell wall integrity pathway, linking the MAP kinase module to the upstream activator protein kinase C. PLoS Genet. 2014;10:e1004582 pubmed publisher
Li Z, Jia L, Wang J, Wu X, Shi G, Lu C, et al. Discovery of novel 17-phenylethylaminegeldanamycin derivatives as potent Hsp90 inhibitors. Chem Biol Drug Des. 2015;85:181-8 pubmed publisher
González Feliciano J, Hernandez Perez M, Estrella L, Colón López D, Lopez A, Martinez M, et al. The role of HuR in the post-transcriptional regulation of interleukin-3 in T cells. PLoS ONE. 2014;9:e92457 pubmed publisher
McDonald L, Ferrari N, Terry A, Bell M, Mohammed Z, Orange C, et al. RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland. Dis Model Mech. 2014;7:525-34 pubmed publisher
González Vallinas M, Molina S, Vicente G, Sánchez Martínez R, Vargas T, García Risco M, et al. Modulation of estrogen and epidermal growth factor receptors by rosemary extract in breast cancer cells. Electrophoresis. 2014;35:1719-27 pubmed publisher
Liu Y, Li Z, Wu L, Wang Z, Wang X, Yu Y, et al. MiRNA-125a-5p: a regulator and predictor of gefitinib's effect on nasopharyngeal carcinoma. Cancer Cell Int. 2014;14:24 pubmed publisher
Wattenberg M, Kwilas A, Gameiro S, Dicker A, Hodge J. Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Br J Cancer. 2014;110:1472-80 pubmed publisher
Milano G, Raucci A, Scopece A, Daniele R, Guerrini U, Sironi L, et al. Doxorubicin and trastuzumab regimen induces biventricular failure in mice. J Am Soc Echocardiogr. 2014;27:568-79 pubmed publisher
Lozy F, Cai McRae X, Teplova I, Price S, Reddy A, Bhanot G, et al. ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 loss. Autophagy. 2014;10:662-76 pubmed publisher
Carpenter R, Paw I, Dewhirst M, Lo H. Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells. Oncogene. 2015;34:546-57 pubmed publisher
Ebeling S, Naumann K, Pollok S, Wardecki T, Vidal Y Sy S, Nascimento J, et al. From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract. PLoS ONE. 2014;9:e86147 pubmed publisher
Schulz R, Streller F, Scheel A, Ruschoff J, Reinert M, Dobbelstein M, et al. HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer. Cell Death Dis. 2014;5:e980 pubmed publisher
Slanina H, Mündlein S, Hebling S, Schubert Unkmeir A. Role of epidermal growth factor receptor signaling in the interaction of Neisseria meningitidis with endothelial cells. Infect Immun. 2014;82:1243-55 pubmed publisher
Alvarez E, Castello A, Carrasco L, Izquierdo J. Poliovirus 2A protease triggers a selective nucleo-cytoplasmic redistribution of splicing factors to regulate alternative pre-mRNA splicing. PLoS ONE. 2013;8:e73723 pubmed publisher
Jørgensen M, Bæk R, Pedersen S, Søndergaard E, Kristensen S, Varming K. Extracellular Vesicle (EV) Array: microarray capturing of exosomes and other extracellular vesicles for multiplexed phenotyping. J Extracell Vesicles. 2013;2: pubmed publisher
Hudy M, Proud D. Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells. Respir Res. 2013;14:88 pubmed publisher
Vetterkind S, Poythress R, Lin Q, Morgan K. Hierarchical scaffolding of an ERK1/2 activation pathway. Cell Commun Signal. 2013;11:65 pubmed publisher
Twyffels L, Wauquier C, Soin R, Decaestecker C, Gueydan C, Kruys V. A masked PY-NLS in Drosophila TIS11 and its mammalian homolog tristetraprolin. PLoS ONE. 2013;8:e71686 pubmed publisher
Akhtar S, Yousif M, Dhaunsi G, Sarkhouh F, Chandrasekhar B, Attur S, et al. Activation of ErbB2 and Downstream Signalling via Rho Kinases and ERK1/2 Contributes to Diabetes-Induced Vascular Dysfunction. PLoS ONE. 2013;8:e67813 pubmed publisher
Harrison Pitner M, Saavedra H. Cdk4 and nek2 signal binucleation and centrosome amplification in a her2+ breast cancer model. PLoS ONE. 2013;8:e65971 pubmed publisher
Tardáguila M, Mira E, García Cabezas M, Feijoo A, Quintela Fandino M, Azcoitia I, et al. CX3CL1 promotes breast cancer via transactivation of the EGF pathway. Cancer Res. 2013;73:4461-73 pubmed publisher
Osaki L, Gama P. MAPKs and signal transduction in the control of gastrointestinal epithelial cell proliferation and differentiation. Int J Mol Sci. 2013;14:10143-61 pubmed publisher
Perez Pinera P, Ousterout D, Brunger J, Farin A, Glass K, Guilak F, et al. Synergistic and tunable human gene activation by combinations of synthetic transcription factors. Nat Methods. 2013;10:239-42 pubmed publisher
Venigalla R, Turner M. RNA-binding proteins as a point of convergence of the PI3K and p38 MAPK pathways. Front Immunol. 2012;3:398 pubmed publisher
Ravichandran A, Low B. SmgGDS antagonizes BPGAP1-induced Ras/ERK activation and neuritogenesis in PC12 cell differentiation. Mol Biol Cell. 2013;24:145-56 pubmed publisher
Akhtar S, Yousif M, Chandrasekhar B, Benter I. Activation of EGFR/ERBB2 via pathways involving ERK1/2, P38 MAPK, AKT and FOXO enhances recovery of diabetic hearts from ischemia-reperfusion injury. PLoS ONE. 2012;7:e39066 pubmed publisher
Latorre E, Tebaldi T, Viero G, Spartà A, Quattrone A, Provenzani A. Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells. Mol Cancer. 2012;11:13 pubmed publisher
Mahat D, Brennan Laun S, Fialcowitz White E, Kishor A, Ross C, Pozharskaya T, et al. Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1. PLoS ONE. 2012;7:e33194 pubmed publisher
David Gerecht P, Taylor M, Port J. Intracellular localization and interaction of mRNA binding proteins as detected by FRET. BMC Cell Biol. 2010;11:69 pubmed publisher
Khabar K. Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements. Cell Mol Life Sci. 2010;67:2937-55 pubmed publisher
Perlewitz A, Nafz B, Skalweit A, Fähling M, Persson P, Thiele B. Aldosterone and vasopressin affect {alpha}- and {gamma}-ENaC mRNA translation. Nucleic Acids Res. 2010;38:5746-60 pubmed publisher
Tsai N, Lin Y, Tsui Y, Wei L. Dual action of epidermal growth factor: extracellular signal-stimulated nuclear-cytoplasmic export and coordinated translation of selected messenger RNA. J Cell Biol. 2010;188:325-33 pubmed publisher
Cho S, Zhang J, Chen X. RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability. Nucleic Acids Res. 2010;38:2256-67 pubmed publisher
Liu H, Buus R, Clague M, Urbé S. Regulation of ErbB2 receptor status by the proteasomal DUB POH1. PLoS ONE. 2009;4:e5544 pubmed publisher
product information
SKU :
2165P
Product-Name :
HER2/ErbB2 (29D8) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, (M, R)
Applications :
Flow cytometry
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
185 kDa
Host :
Rabbit
Target :
HER2/ErbB2
Primary-Protein :
HER2
Alt-Names :
CD340,ERBB2,HER-2,HER-2/neu,HER2,MLN 19,MLN19,Metastatic lymph node gene 19 protein,NEU,NGL,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Receptor tyrosine-protein kinase erbB-2,TKR1,Tyrosine kinase-type cell surface receptor HER2,c-erb B2/neu protein,erbB-2,herstatin,neuroblastoma/glioblastoma derived oncogene homolog,p185erbB2,v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog),v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.