product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
DNMT3A Antibody
catalog :
2160
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
western blot, immunoprecipitation, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; fig 4b
  • western blot knockout validation; mouse; 1:2000; fig s1a
Cole C, Verdoni A, Ketkar S, Leight E, Russler Germain D, Lamprecht T, et al. PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia. J Clin Invest. 2016;126:85-98 pubmed publisher
  • western blot; mouse
  • western blot; human
Liao J, Karnik R, Gu H, Ziller M, Clement K, Tsankov A, et al. Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Nat Genet. 2015;47:469-78 pubmed publisher
  • western blot; mouse; fig s9
Hu W, Dooley J, Chung S, Chandramohan D, Cimmino L, Mukherjee S, et al. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 2015;125:2206-16 pubmed publisher
Guo W, Chen J, Yang Y, Zhu J, Wu J. Epigenetic programming of Dnmt3a mediated by AP2α is required for granting preadipocyte the ability to differentiate. Cell Death Dis. 2016;7:e2496 pubmed publisher
Chu N, Wu Z, Zhang X, Fang S, Wang W, Cheng Y. Molecular mechanism of yisui shengxue granule, a complex chinese medicine, on thalassemia patients suffering from hemolysis and anemia of erythrocytes. Evid Based Complement Alternat Med. 2014;2014:213782 pubmed publisher
Santanam U, Zanesi N, Efanov A, Costinean S, Palamarchuk A, Hagan J, et al. Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression. Proc Natl Acad Sci U S A. 2010;107:12210-5 pubmed publisher
product information
SKU :
2160S
Product-Name :
DNMT3A Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (B)
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
130
Host :
Rabbit
Target :
DNMT3A
Primary-Protein :
DNMT3A
Alt-Names :
DNA (cytosine-5)-methyltransferase 3A,DNA (cytosine-5-)-methyltransferase 3 alpha,DNA MTase HsaIIIA,DNA cytosine methyltransferase 3A2,DNA methyltransferase HsaIIIA,DNM3A,DNMT3A,DNMT3A2,M.HsaIIIA
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.