product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Jagged1 (1C4) Rabbit mAb
catalog :
2155
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
1C4
reactivity :
human
application :
western blot, immunohistochemistry - frozen section
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:800; loading ...; fig 1b
Asnaghi L, Tripathy A, Yang Q, Kaur H, Hanaford A, Yu W, et al. Targeting Notch signaling as a novel therapy for retinoblastoma. Oncotarget. 2016;7:70028-70044 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5e
Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100
Lim K, Brandt W, Heth J, Muraszko K, Fan X, Bar E, et al. Lateral inhibition of Notch signaling in neoplastic cells. Oncotarget. 2015;6:1666-77 pubmed
Nguyen P, Huang C, Sugii S, Cheong S, Choo K. Selective activation of miRNAs of the primate-specific chromosome 19 miRNA cluster (C19MC) in cancer and stem cells and possible contribution to regulation of apoptosis. J Biomed Sci. 2017;24:20 pubmed publisher
Peterhans C, Lally C, Ostermaier M, Sommer M, Standfuss J. Functional map of arrestin binding to phosphorylated opsin, with and without agonist. Sci Rep. 2016;6:28686 pubmed publisher
Kluba M, Engelborghs Y, Hofkens J, Mizuno H. Inhibition of Receptor Dimerization as a Novel Negative Feedback Mechanism of EGFR Signaling. PLoS ONE. 2015;10:e0139971 pubmed publisher
McCubrey J, Steelman L, Chappell W, Abrams S, Montalto G, Cervello M, et al. Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response. Oncotarget. 2012;3:954-87 pubmed
Kim I, Kwak H, Lee H, Hyun S, Jeong S. ?-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells. Nucleic Acids Res. 2012;40:6863-72 pubmed publisher
Ghosh S, Paez Cortez J, Boppidi K, Vasconcelos M, Roy M, CARDOSO W, et al. Activation dynamics and signaling properties of Notch3 receptor in the developing pulmonary artery. J Biol Chem. 2011;286:22678-87 pubmed publisher
Burnstock G, Verkhratsky A. Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death. Cell Death Dis. 2010;1:e9 pubmed publisher
Goldoni S, Humphries A, Nyström A, Sattar S, Owens R, McQuillan D, et al. Decorin is a novel antagonistic ligand of the Met receptor. J Cell Biol. 2009;185:743-54 pubmed publisher
Seil M, Fontanils U, Etxebarria I, Pochet S, Garcia Marcos M, Marino A, et al. Pharmacological evidence for the stimulation of NADPH oxidase by P2X(7) receptors in mouse submandibular glands. Purinergic Signal. 2008;4:347-55 pubmed publisher
product information
SKU :
2155S
Product-Name :
Jagged1 (1C4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Western blot
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
180
Host :
Rabbit
Target :
Jagged1
Primary-Protein :
JAG1
Alt-Names :
AGS,AHD,AWS,CD339,JAG1,JAGL1,Jagged1,MGC104644,Protein jagged-1,hJ1,jagged 1 (Alagille syndrome)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.