Axin2 (76G6) Rabbit mAb | Cell Signaling Technology 2151 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Axin2 (76G6) Rabbit mAb

catalog :

2151

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

76G6

reactivity :

human

application :

western blot, immunoprecipitation, western blot knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; 1:500; fig 3-s1	Lebensohn A, Dubey R, Neitzel L, Tacchelly Benites O, Yang E, Marceau C, et al. Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. elife. 2016;5: pubmed publisher
western blot; human; loading ...; fig s12f	Harper C, Woodcock D, Lam C, Garcia Albornoz M, Adamson A, Ashall L, et al. Temperature regulates NF-?B dynamics and function through timing of A20 transcription. Proc Natl Acad Sci U S A. 2018;115:E5243-E5249 pubmed publisher
western blot; human; fig 1	Li Y, Lu W, Saini S, Moukha Chafiq O, Pathak V, Ananthan S. Identification of quinazoline compounds as novel potent inhibitors of Wnt/?-catenin signaling in colorectal cancer cells. Oncotarget. 2016;7:11263-70 pubmed publisher
western blot; human; fig 1e	Shi J, Liu Y, Xu X, Zhang W, Yu T, Jia J, et al. Deubiquitinase USP47/UBP64E Regulates Î²-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling. Mol Cell Biol. 2015;35:3301-11 pubmed publisher
western blot; human; fig 5	Cheng Y, Phoon Y, Jin X, Chong S, Ip J, Wong B, et al. Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment. Oncotarget. 2015;6:14428-39 pubmed
western blot; human; 1:1000; fig 2	Xue J, Chen Y, Wu Y, Wang Z, Zhou A, Zhang S, et al. Tumour suppressor TRIM33 targets nuclear Î²-catenin degradation. Nat Commun. 2015;6:6156 pubmed publisher
	Pedersen N, Thorvaldsen T, Schultz S, Wenzel E, Stenmark H. Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity. PLoS ONE. 2016;11:e0160507 pubmed publisher
	Mazzoni S, Petty E, Stoffel E, Fearon E. An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function. Neoplasia. 2015;17:463-72 pubmed publisher
	Atkinson J, Rank K, Zeng Y, Capen A, Yadav V, Manro J, et al. Activating the Wnt/Î²-Catenin Pathway for the Treatment of Melanoma--Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3. PLoS ONE. 2015;10:e0125028 pubmed publisher
	James R, Davidson K, Bosch K, Biechele T, Robin N, Taylor R, et al. WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling. PLoS ONE. 2012;7:e50457 pubmed publisher
	Callow M, Tran H, Phu L, Lau T, Lee J, Sandoval W, et al. Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling. PLoS ONE. 2011;6:e22595 pubmed publisher
	Fancy S, Harrington E, Yuen T, Silbereis J, Zhao C, Baranzini S, et al. Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nat Neurosci. 2011;14:1009-16 pubmed publisher

product information

SKU :

2151S

Product-Name :

Axin2 (76G6) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

Applications :

Immunoprecipitation

Product-Category :

Developmental Biology

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

95, 98

Host :

Rabbit

Target :

Axin2

Primary-Protein :

axin 2

Alt-Names :

AXIN2,AXN2,Axil,Axin-2,Axin-like protein,Axis inhibition protein 2,Conductin,DKFZp781B0869,MGC10366,MGC126582,axin 2

more info or order :

Cell Signaling Technology product webpage