product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
β-Tubulin Antibody
catalog :
2146
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 31
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4a
Fischietti M, Eckerdt F, Blyth G, Arslan A, Mati W, Oku C, et al. Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma. Oncogene. 2021;40:3273-3286 pubmed publisher
  • western blot; mouse; loading ...; fig s5c
Lee J, Hall J, Kroehling L, Wu L, Najar T, Nguyen H, et al. Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease. Cell. 2020;180:79-91.e16 pubmed publisher
  • immunocytochemistry; human; 1:10; fig 2
  • western blot; human; 1:2000; fig 1
Liu C, Lin S, Hsu H, Yang S, Lin C, Yang M, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016;7:11798 pubmed publisher
  • immunocytochemistry; human; fig 5
Al Nakouzi N, Wang C, Beraldi E, Jäger W, Ettinger S, Fazli L, et al. Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis. EMBO Mol Med. 2016;8:761-78 pubmed publisher
  • western blot; human; 1:2000; fig 6
Ribeiro J, Schorl C, Yano N, Romano N, Kim K, Singh R, et al. HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells. J Ovarian Res. 2016;9:28 pubmed publisher
  • western blot; mouse; fig 1A
Chen L, DeWispelaere A, Dastvan F, Osborne W, Blechner C, Windhorst S, et al. Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity. PLoS ONE. 2016;11:e0155726 pubmed publisher
  • western blot; human; fig s1
Karvela M, Baquero P, Kuntz E, Mukhopadhyay A, Mitchell R, Allan E, et al. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016;12:936-48 pubmed publisher
  • immunohistochemistry - paraffin section; human; 0.5 ug/ml; fig st1
  • western blot; human; fig 4
Kaur A, Webster M, Marchbank K, Behera R, Ndoye A, Kugel C, et al. sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature. 2016;532:250-4 pubmed publisher
  • western blot; human; fig 1d
Mason J, Davison Versagli C, Leliaert A, Pape D, McCallister C, Zuo J, et al. Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells. Cell Death Differ. 2016;23:1271-82 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Zhao Y, Wei J, Tian Q, Liu A, Yi Y, Einhorn T, et al. Progranulin suppresses titanium particle induced inflammatory osteolysis by targeting TNFα signaling. Sci Rep. 2016;6:20909 pubmed publisher
  • western blot; mouse; 1:1500; fig s1d
Nakazawa M, Eisinger Mathason T, Sadri N, Ochocki J, Gade T, Amin R, et al. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth. Nat Commun. 2016;7:10539 pubmed publisher
  • western blot; human; 1:1000; fig 4
Roßner F, Gieseler C, Morkel M, Royer H, Rivera M, Bläker H, et al. Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancer. Oncogenesis. 2016;5:e187 pubmed publisher
Wu J, Xiang S, Zhang M, Fang B, Huang H, Kwon O, et al. Histone deacetylase 6 (HDAC6) deacetylates extracellular signal-regulated kinase 1 (ERK1) and thereby stimulates ERK1 activity. J Biol Chem. 2018;293:1976-1993 pubmed publisher
Berrout J, Kyriakopoulou E, Moparthi L, Hogea A, Berrout L, Ivan C, et al. TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p. Nat Commun. 2017;8:947 pubmed publisher
Palmer C, Bruckner R, Paulo J, Kazak L, Long J, Mina A, et al. Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue. Mol Metab. 2017;6:1212-1225 pubmed publisher
Wang B, Fu X, Zhu M, Du M. Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation. J Mol Cell Biol. 2017;9:338-349 pubmed publisher
Wang L, Scott I, Zhu L, Wu K, Han K, Chen Y, et al. GCN5L1 modulates cross-talk between mitochondria and cell signaling to regulate FoxO1 stability and gluconeogenesis. Nat Commun. 2017;8:523 pubmed publisher
Bloh K, Bialk P, Gopalakrishnapillai A, Kolb E, Kmiec E. CRISPR/Cas9-Directed Reassignment of the GATA1 Initiation Codon in K562 Cells to Recapitulate AML in Down Syndrome. Mol Ther Nucleic Acids. 2017;7:288-298 pubmed publisher
Machado A, Rodríguez Expósito E, Lopez M, Hernandez M. Phylogenetic analysis of the genus Laparocerus, with comments on colonisation and diversification in Macaronesia (Coleoptera, Curculionidae, Entiminae). Zookeys. 2017;:1-77 pubmed publisher
Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed publisher
Nyati K, Masuda K, Zaman M, Dubey P, Millrine D, Chalise J, et al. TLR4-induced NF-?B and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a. Nucleic Acids Res. 2017;45:2687-2703 pubmed publisher
King J, Ung N, Paing M, Contreras J, Alberti M, Fernando T, et al. Regulation of Marginal Zone B-Cell Differentiation by MicroRNA-146a. Front Immunol. 2016;7:670 pubmed publisher
Das S, Jackson W, Prasain J, Hanna A, Bailey S, Tucker J, et al. Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. Sci Rep. 2017;7:40773 pubmed publisher
Yang H, Zhao X, Zhao L, Liu L, Li J, Jia W, et al. PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma. Oncotarget. 2016;7:72131-72147 pubmed publisher
Fan J, Ruan J, Liu W, Zhu L, Zhu X, Yi H, et al. miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone. Oncotarget. 2016;7:70613-70622 pubmed publisher
Ki D, He S, Rodig S, Look A. Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors. Oncogene. 2017;36:1058-1068 pubmed publisher
Powers J, Tsanov K, Pearson D, Roels F, Spina C, EBRIGHT R, et al. Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. Nature. 2016;535:246-51 pubmed publisher
Reis F, Branquinho J, Brandão B, Guerra B, Silva I, Frontini A, et al. Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice. Aging (Albany NY). 2016;8:1201-22 pubmed publisher
Winick Ng W, Caetano F, Winick Ng J, Morey T, Heit B, Rylett R. 82-kDa choline acetyltransferase and SATB1 localize to ?-amyloid induced matrix attachment regions. Sci Rep. 2016;6:23914 pubmed publisher
Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed publisher
Wang X, He G, Mai K, Xu W, Zhou H. Differential regulation of taurine biosynthesis in rainbow trout and Japanese flounder. Sci Rep. 2016;6:21231 pubmed publisher
product information
SKU :
2146S
Product-Name :
β-Tubulin Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, Z, B, (X)
Applications :
Flow cytometry
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
55
Host :
Rabbit
Target :
tubulin beta-2
Primary-Protein :
TUBB
Alt-Names :
M40,MGC117247,MGC16435,OK/SW-cl.56,TBB5,TUBB,TUBB1,TUBB5,Tubulin beta chain,Tubulin beta-5 chain,beta 5-tubulin,beta Ib tubulin,beta-4 tubulin,tubulin beta polypeptide,tubulin beta-1 chain,tubulin, beta,tubulin, beta polypeptide
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.