product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rictor Antibody
catalog :
2140
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5c
  • western blot; mouse; 1:1000; loading ...; fig 5a
Poulopoulos A, Murphy A, Ozkan A, Davis P, Hatch J, Kirchner R, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature. 2019;565:356-360 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3g
Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher
  • western blot; human; loading ...; fig 3b
Hau A, Leivo M, Gilder A, Hu J, Gonias S, Hansel D. mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer. Cell Signal. 2017;29:96-106 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2h
Eid S, Boutary S, Braych K, Sabra R, Massaad C, Hamdy A, et al. mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes. Antioxid Redox Signal. 2016;25:703-719 pubmed
  • western blot; human; 1:1000; fig 3
Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  • western blot; mouse; 1:1000
Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5a
Aimi F, Georgiopoulou S, Kalus I, Lehner F, Hegglin A, Limani P, et al. Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. Sci Rep. 2015;5:17705 pubmed publisher
  • western blot; human; loading ...; fig 3c
Chen H, Huang W, Yang L, Lin C. The PTEN-AKT-mTOR/RICTOR Pathway in Nasal Natural Killer Cell Lymphoma Is Activated by miR-494-3p via PTEN But Inhibited by miR-142-3p via RICTOR. Am J Pathol. 2015;185:1487-99 pubmed publisher
  • western blot; mouse; loading ...; fig 3b
Shi Y, Chen J, Karner C, Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Proc Natl Acad Sci U S A. 2015;112:4678-83 pubmed publisher
  • western blot; human; fig 5
Kocher B, White L, Piwnica Worms D. DAPK3 suppresses acini morphogenesis and is required for mouse development. Mol Cancer Res. 2015;13:358-67 pubmed publisher
  • western blot; human
Raman N, Nayak A, Muller S. mTOR signaling regulates nucleolar targeting of the SUMO-specific isopeptidase SENP3. Mol Cell Biol. 2014;34:4474-84 pubmed publisher
Shimobayashi M, Albert V, Woelnerhanssen B, Frei I, Weissenberger D, Meyer Gerspach A, et al. Insulin resistance causes inflammation in adipose tissue. J Clin Invest. 2018;128:1538-1550 pubmed publisher
Bhalla M, Law D, Dowd G, Ireton K. Host Serine/Threonine Kinases mTOR and Protein Kinase C-? Promote InlB-Mediated Entry of Listeria monocytogenes. Infect Immun. 2017;85: pubmed publisher
Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
Lamming D, Mihaylova M, Katajisto P, Baar E, Yilmaz O, Hutchins A, et al. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. Aging Cell. 2014;13:911-7 pubmed publisher
Festuccia W, Pouliot P, Bakan I, Sabatini D, Laplante M. Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide. PLoS ONE. 2014;9:e95432 pubmed publisher
Heikamp E, Patel C, Collins S, Waickman A, Oh M, Sun I, et al. The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex. Nat Immunol. 2014;15:457-64 pubmed publisher
Hasumi Y, Baba M, Ajima R, Hasumi H, Valera V, Klein M, et al. Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2. Proc Natl Acad Sci U S A. 2009;106:18722-7 pubmed publisher
product information
SKU :
2140S
Product-Name :
Rictor Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
200
Host :
Rabbit
Target :
Rictor
Primary-Protein :
Rictor
Alt-Names :
AVO3 homolog,DKFZp686B11164,KIAA1999,MGC39830,PIA,RICTOR,RICTR,RPTOR independent companion of MTOR, complex 2,Rapamycin-insensitive companion of mTOR,TORC2-specific protein AVO3,hAVO3,mAVO3,pianissimo
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.