product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
LSD1 Antibody
catalog :
2139S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/DilutionReference
  • western blot (knockout validation); mouse; 1:1000; fig 2
  • western blot; human; 1:1000; fig 2
  • immunoprecipitation; human; fig 2
Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; fig 3
Nagasawa S, Sedukhina A, Nakagawa Y, Maeda I, Kubota M, Ohnuma S, et al. LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition. PLoS ONE. 2015;10:e0118002 pubmed publisher
  • western blot; mouse; 1:5000
Wang Q, Chikina M, Pincas H, Sealfon S. Homer1 alternative splicing is regulated by gonadotropin-releasing hormone and modulates gonadotropin gene expression. Mol Cell Biol. 2014;34:1747-56 pubmed publisher
Billing A, Ben Hamidane H, Dib S, Cotton R, Bhagwat A, Kumar P, et al. Comprehensive transcriptomic and proteomic characterization of human mesenchymal stem cells reveals source specific cellular markers. Sci Rep. 2016;6:21507 pubmed publisher
Chang T, Hsieh F, Zebisch M, Harlos K, Elegheert J, Jones E. Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan. elife. 2015;4: pubmed publisher
Harten S, Oey H, Bourke L, Bharti V, Isbel L, Daxinger L, et al. The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers. BMC Biol. 2015;13:21 pubmed publisher
Zecchini V, Madhu B, Russell R, Pértega-Gomes N, Warren A, Gaude E, et al. Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. EMBO J. 2014;33:1365-82 pubmed publisher
Nicholson T, Singh A, Su H, Hevi S, Wang J, Bajko J, et al. A hypomorphic lsd1 allele results in heart development defects in mice. PLoS ONE. 2013;8:e60913 pubmed publisher
Wen L, Chen Y, Zeng L, Zhao F, Li R, Liu Y, et al. Triptolide induces cell-cycle arrest and apoptosis of human multiple myeloma cells in vitro via altering expression of histone demethylase LSD1 and JMJD2B. Acta Pharmacol Sin. 2012;33:109-19 pubmed publisher
product information
SKU :
2139S
Product-Name :
LSD1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
110
Host :
Rabbit
Target :
LSD1
Primary-Protein :
LSD1
Alt-Names :
AOF2,BHC110,BRAF35-HDAC complex protein BHC110,FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit,Flavin-containing amine oxidase domain-containing protein 2,KDM1,KDM1A,KIAA0601,LSD1,Lysine-specific histone demethylase 1A,amine oxidase (flavin containing) domain 2,lysine (K)-specific demethylase 1,lysine (K)-specific demethylase 1A,lysine-specific histone demethylase 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.