product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SRC-3 (5E11) Rabbit mAb
catalog :
2126
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
5E11
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation, immunohistochemistry knockout validation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 4
  • immunoprecipitation; human; fig 4
Liu X, Li H, Rajurkar M, Li Q, Cotton J, Ou J, et al. Tead and AP1 Coordinate Transcription and Motility. Cell Rep. 2016;14:1169-1180 pubmed publisher
  • western blot knockout validation; mouse; fig 1
  • immunohistochemistry - paraffin section; mouse; fig 1
Chen X, Qin L, Liu Z, Liao L, Martin J, Xu J. Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015;11:1056-72 pubmed publisher
  • immunohistochemistry knockout validation; mouse; fig 1
Tien J, Liao L, Liu Y, Liu Z, Lee D, Wang F, et al. The steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostate. Int J Biol Sci. 2014;10:1116-27 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Patrick N, Griggs C, Icenogle A, Gilpatrick M, Kadiyala V, Jaime Frias R, et al. Class I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1. J Steroid Biochem Mol Biol. 2017;167:1-13 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:75; loading ...; fig 1a
  • western blot; human; 1:1000; loading ...; fig 1d
Ory V, Tassi E, Cavalli L, Sharif G, Saenz F, Baker T, et al. The nuclear coactivator amplified in breast cancer 1 maintains tumor-initiating cells during development of ductal carcinoma in situ. Oncogene. 2014;33:3033-42 pubmed publisher
Zhao N, Cao J, Xu L, Tang Q, Dobrolecki L, Lv X, et al. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018;128:1283-1299 pubmed publisher
Fleet T, Zhang B, Lin F, Zhu B, Dasgupta S, Stashi E, et al. SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis. Proc Natl Acad Sci U S A. 2015;112:E6068-77 pubmed publisher
Luderer H, Gori F, Demay M. Lymphoid enhancer-binding factor-1 (LEF1) interacts with the DNA-binding domain of the vitamin D receptor. J Biol Chem. 2011;286:18444-51 pubmed publisher
product information
SKU :
2126S
Product-Name :
SRC-3 (5E11) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
160
Host :
Rabbit
Target :
SRC-3
Primary-Protein :
SRC-3
Alt-Names :
ACTR,AIB-1,AIB1,Amplified in breast cancer 1 protein,BHLHE42,CAGH16,CBP-interacting protein,CTG26,Class E basic helix-loop-helix protein 42,KAT13B,MGC141848,NCOA3,NCoA-3,Nuclear receptor coactivator 3,RAC-3,RAC3,Receptor-associated coactivator 3,SRC-3,SRC3,Steroid receptor coactivator protein 3,TNRC14,TNRC16,TRAM-1,TRAM1,Thyroid hormone receptor activator molecule 1,pCIP
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.