product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
RhoA (67B9) Rabbit mAb
catalog :
2117P
quantity :
40 ul
price :
123 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat, cow
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 15
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; 1:1000; fig s1
Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, et al. F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling. Nat Commun. 2016;7:10493 pubmed publisher
  • western blot; human
Fujimura K, Choi S, Wyse M, Strnadel J, Wright T, Klemke R. Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels. J Biol Chem. 2015;290:29907-19 pubmed publisher
  • western blot; human; fig 3a
Liu X, Yao J, Tripathi D, Ding Z, Xu Y, Sun M, et al. Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis. Oncogene. 2015;34:2450-60 pubmed publisher
  • western blot; human; fig 1
Ibeawuchi S, Agbor L, Quelle F, Sigmund C. Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors. J Biol Chem. 2015;290:19208-17 pubmed publisher
  • western blot; mouse; fig 3
Arroyo A, Camoletto P, Morando L, Sassoè-Pognetto M, Giustetto M, Van Veldhoven P, et al. Pharmacological reversion of sphingomyelin-induced dendritic spine anomalies in a Niemann Pick disease type A mouse model. EMBO Mol Med. 2014;6:398-413 pubmed publisher
Rohani M, PILCHER B, Chen P, Parks W. Cdc42 inhibits ERK-mediated collagenase-1 (MMP-1) expression in collagen-activated human keratinocytes. J Invest Dermatol. 2014;134:1230-7 pubmed publisher
Gu H, Yu S, Gutekunst C, Gross R, Wei L. Inhibition of the Rho signaling pathway improves neurite outgrowth and neuronal differentiation of mouse neural stem cells. Int J Physiol Pathophysiol Pharmacol. 2013;5:11-20 pubmed
Tang X, Jin R, Qu G, Wang X, Li Z, Yuan Z, et al. GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway. Cancer Res. 2013;73:6206-18 pubmed publisher
Xue H, Li Y, Everett E, Ryan K, Peng L, Porecha R, et al. Ameloblasts require active RhoA to generate normal dental enamel. Eur J Oral Sci. 2013;121:293-302 pubmed publisher
Zhang S, Zhou X, Lang R, Guo F. RhoA of the Rho family small GTPases is essential for B lymphocyte development. PLoS ONE. 2012;7:e33773 pubmed publisher
Zaytseva Y, Rychahou P, Gulhati P, Elliott V, Mustain W, O'Connor K, et al. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012;72:1504-17 pubmed publisher
Kamanova J, Kofronova O, Masin J, Genth H, Vojtova J, Linhartova I, et al. Adenylate cyclase toxin subverts phagocyte function by RhoA inhibition and unproductive ruffling. J Immunol. 2008;181:5587-97 pubmed
Ponsaerts R, D'hondt C, Hertens F, Parys J, Leybaert L, Vereecke J, et al. RhoA GTPase switch controls Cx43-hemichannel activity through the contractile system. PLoS ONE. 2012;7:e42074 pubmed publisher
Bielenberg D, Seth A, Shimizu A, Pelton K, Cristofaro V, Ramachandran A, et al. Increased smooth muscle contractility in mice deficient for neuropilin 2. Am J Pathol. 2012;181:548-59 pubmed publisher
Worzfeld T, Swiercz J, Looso M, Straub B, Sivaraj K, Offermanns S. ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis. J Clin Invest. 2012;122:1296-305 pubmed publisher
product information
SKU :
2117P
Product-Name :
RhoA (67B9) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk, B
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
21
Host :
Rabbit
Target :
RhoA
Primary-Protein :
RhoA
Alt-Names :
ARH12,ARHA,Aplysia ras-related homolog 12,RHO12,RHOA,RHOH12,Rho cDNA clone 12,Transforming protein RhoA,h12,oncogene RHO H12,ras homolog gene family, member A,small GTP binding protein RhoA
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.