product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Src (36D10) Rabbit mAb
catalog :
2109S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 5
Liu M, Feng L, Sun P, Liu W, Wu W, Jiang B, et al. A Novel Bufalin Derivative Exhibited Stronger Apoptosis-Inducing Effect than Bufalin in A549 Lung Cancer Cells and Lower Acute Toxicity in Mice. PLoS ONE. 2016;11:e0159789 pubmed publisher
  • western blot; human; 1:1000; fig 3
Clark D, Fondrie W, Yang A, Mao L. Triple SILAC quantitative proteomic analysis reveals differential abundance of cell signaling proteins between normal and lung cancer-derived exosomes. J Proteomics. 2016;133:161-9 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • western blot; human
Cunnick J, Kim S, Hadsell J, Collins S, Cerra C, Reiser P, et al. Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland. Oncogene. 2015;34:2640-9 pubmed publisher
  • western blot; human; fig 2
Wang S, Cui H, Liu Y, Zhao P, Zhang Y, Fu Z, et al. CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells. Oncotarget. 2015;6:243-57 pubmed
  • western blot; mouse; 1:8000
Tang Y, Ye M, Du Y, Qiu X, Lv X, Yang W, et al. EGFR signaling upregulates surface expression of the GluN2B-containing NMDA receptor and contributes to long-term potentiation in the hippocampus. Neuroscience. 2015;304:109-21 pubmed publisher
  • immunocytochemistry; human; fig 2
Ward J, Ha J, Jayaraman M, Dhanasekaran D. LPA-mediated migration of ovarian cancer cells involves translocalization of Gαi2 to invadopodia and association with Src and β-pix. Cancer Lett. 2015;356:382-91 pubmed publisher
  • western blot; human
Spring K, Fournier P, Lapointe L, Chabot C, Roussy J, Pommey S, et al. The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis. Oncogene. 2015;34:5536-47 pubmed publisher
  • immunocytochemistry; human; 2 ug/ml; fig 6
  • western blot; human; 1:1000; fig 6
Zoppi N, Chiarelli N, Cinquina V, Ritelli M, Colombi M. GLUT10 deficiency leads to oxidative stress and non-canonical αvβ3 integrin-mediated TGFβ signalling associated with extracellular matrix disarray in arterial tortuosity syndrome skin fibroblasts. Hum Mol Genet. 2015;24:6769-87 pubmed publisher
  • western blot; mouse
Andersson L, Scharin Tang M, Lundqvist A, Lindbom M, Mardani I, Fogelstrand P, et al. Rip2 modifies VEGF-induced signalling and vascular permeability in myocardial ischaemia. Cardiovasc Res. 2015;107:478-86 pubmed publisher
  • western blot; human
Guo W, Liu R, Bhardwaj G, Yang J, Changou C, Ma A, et al. Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor. Cell Death Dis. 2014;5:e1409 pubmed publisher
  • immunocytochemistry; human
  • immunohistochemistry; human
Ghaffari A, Hoskin V, Szeto A, Hum M, Liaghati N, Nakatsu K, et al. A novel role for ezrin in breast cancer angio/lymphangiogenesis. Breast Cancer Res. 2014;16:438 pubmed publisher
  • western blot; human
Hong Y, Kim J, Pectasides E, Fox C, Hong S, Ma Q, et al. Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models. PLoS ONE. 2014;9:e109440 pubmed publisher
García-Recio S, Pastor-Arroyo E, Marín-Aguilera M, Almendro V, Gascon P. The Transmodulation of HER2 and EGFR by Substance P in Breast Cancer Cells Requires c-Src and Metalloproteinase Activation. PLoS ONE. 2015;10:e0129661 pubmed publisher
Stateva S, Salas V, Benaim G, Menendez M, Solís D, Villalobo A. Characterization of phospho-(tyrosine)-mimetic calmodulin mutants. PLoS ONE. 2015;10:e0120798 pubmed publisher
Komiya E, Ohnuma K, Yamazaki H, Hatano R, Iwata S, Okamoto T, et al. CD26-mediated regulation of periostin expression contributes to migration and invasion of malignant pleural mesothelioma cells. Biochem Biophys Res Commun. 2014;447:609-15 pubmed publisher
Laurie S, Goss G, Shepherd F, Reaume M, Nicholas G, Philip L, et al. A phase II trial of saracatinib, an inhibitor of src kinases, in previously-treated advanced non-small-cell lung cancer: the princess margaret hospital phase II consortium. Clin Lung Cancer. 2014;15:52-7 pubmed publisher
Xu W, Allbritton N, Lawrence D. SRC kinase regulation in progressively invasive cancer. PLoS ONE. 2012;7:e48867 pubmed publisher
Anbalagan M, Moroz K, Ali A, Carrier L, Glodowski S, Rowan B. Subcellular localization of total and activated Src kinase in African American and Caucasian breast cancer. PLoS ONE. 2012;7:e33017 pubmed publisher
Zaytseva Y, Rychahou P, Gulhati P, Elliott V, Mustain W, O'Connor K, et al. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012;72:1504-17 pubmed publisher
Sakuma Y, Yamazaki Y, Nakamura Y, Yoshihara M, Matsukuma S, Nakayama H, et al. WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors. Lab Invest. 2012;92:371-83 pubmed publisher
product information
SKU :
2109S
Product-Name :
Src (36D10) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, B, Pg, (C)
Applications :
Flow cytometry
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Rabbit
Target :
Src
Primary-Protein :
Src
Alt-Names :
ASV,Proto-oncogene c-Src,Proto-oncogene tyrosine-protein kinase Src,SRC,SRC1,c-SRC,p60-Src,pp60c-src,protooncogene SRC, Rous sarcoma,tyrosine kinase pp60c-src,tyrosine-protein kinase SRC-1,v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.