| Published Application/Species/Dilution | Reference |
|---|
- western blot; mouse; fig 7
| Park J, Kotani T, Konno T, Setiawan J, Kitamura Y, Imada S, et al. Promotion of Intestinal Epithelial Cell Turnover by Commensal Bacteria: Role of Short-Chain Fatty Acids. PLoS ONE. 2016;11:e0156334 pubmed publisher |
- immunocytochemistry; human; fig s5
- western blot; human; fig 2
| Adam A, Lowery A, Martino N, Alsaffar H, Vincent P. Src Family Kinases Modulate the Loss of Endothelial Barrier Function in Response to TNF-α: Crosstalk with p38 Signaling. PLoS ONE. 2016;11:e0161975 pubmed publisher |
- western blot; human; 1:1000; fig 4a
| Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed publisher |
- western blot; human; fig 7
| Ayres Pereira M, Mandel Clausen T, Pehrson C, Mao Y, Resende M, Daugaard M, et al. Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1. PLoS Pathog. 2016;12:e1005831 pubmed publisher |
- western blot; mouse; 1:2000; fig 2
| Burger D, Turner M, Munkonda M, Touyz R. Endothelial Microparticle-Derived Reactive Oxygen Species: Role in Endothelial Signaling and Vascular Function. Oxid Med Cell Longev. 2016;2016:5047954 pubmed publisher |
- western blot; human; fig 4
| Kourtidis A, Anastasiadis P. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016;15:498-505 pubmed publisher |
- western blot; human; 1:2000; fig 4
| Ikeuchi M, Fukumoto Y, Honda T, Kuga T, Saito Y, Yamaguchi N, et al. v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage. Int J Mol Sci. 2016;17: pubmed publisher |
- western blot; human; fig 2
| Segatto I, Massarut S, Boyle R, Baldassarre G, Walker D, Belletti B. Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer. Aging (Albany NY). 2016;8:958-76 pubmed publisher |
- western blot; human; fig 8
| Huang D, Zhao C, Ju R, Kumar A, Tian G, Huang L, et al. VEGF-B inhibits hyperglycemia- and Macugen-induced retinal apoptosis. Sci Rep. 2016;6:26059 pubmed publisher |
- western blot; human; fig 3
| DeRita R, Zerlanko B, Singh A, Lu H, Iozzo R, Benovic J, et al. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase Are Enriched into Prostate Cancer Cell Exosomes. J Cell Biochem. 2016;: pubmed publisher |
- western blot; human; 1:1000; fig 5s1
| Krusche B, Ottone C, Clements M, Johnstone E, Goetsch K, Lieven H, et al. EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells. elife. 2016;5: pubmed publisher |
| Cunnick J, Kim S, Hadsell J, Collins S, Cerra C, Reiser P, et al. Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland. Oncogene. 2015;34:2640-9 pubmed publisher |
| Teng Y, Radde B, Litchfield L, Ivanova M, Prough R, Clark B, et al. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem. 2015;290:15799-811 pubmed publisher |
| Kim B, Lee J, Choi J, Park D, Song H, Park T, et al. Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. Br J Pharmacol. 2015;172:3875-89 pubmed publisher |
| Bunaciu R, Jensen H, Macdonald R, Latocha D, Varner J, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. PLoS ONE. 2015;10:e0135668 pubmed publisher |
- western blot; human; 1:250
| Cai H, Liu W, Xue Y, Shang X, Liu J, Li Z, et al. Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression. J Neuropathol Exp Neurol. 2015;74:25-37 pubmed publisher |
| Galoian K, Qureshi A, D'Ippolito G, Schiller P, Molinari M, Johnstone A, et al. Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1. Int J Oncol. 2015;47:465-72 pubmed publisher |
- other; mouse; 1:1000; fig s1
| Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher |
- western blot; mouse; fig 3
| Park E, Kim N, Ficarro S, Zhang Y, Lee B, Cho A, et al. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat Struct Mol Biol. 2015;22:703-11 pubmed publisher |
| Richter E, Harms M, Ventz K, Gierok P, Chilukoti R, Hildebrandt J, et al. A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin. PLoS ONE. 2015;10:e0122089 pubmed publisher |
- western blot; mouse; fig 8
| Sheng L, Leshchyns'ka I, Sytnyk V. Neural cell adhesion molecule 2 promotes the formation of filopodia and neurite branching by inducing submembrane increases in Ca2+ levels. J Neurosci. 2015;35:1739-52 pubmed publisher |
| Chattopadhyay R, Tinnikov A, Dyukova E, Singh N, Kotla S, Mobley J, et al. 12/15-Lipoxygenase-dependent ROS production is required for diet-induced endothelial barrier dysfunction. J Lipid Res. 2015;56:562-77 pubmed publisher |
- western blot; mouse; fig 2
| De Mario A, Castellani A, Peggion C, Massimino M, Lim D, Hill A, et al. The prion protein constitutively controls neuronal store-operated Ca(2+) entry through Fyn kinase. Front Cell Neurosci. 2015;9:416 pubmed publisher |
| Gorantla S, Zirlik K, Reiter A, Yu C, Illert A, von Bubnoff N, et al. F604S exchange in FIP1L1-PDGFRA enhances FIP1L1-PDGFRA protein stability via SHP-2 and SRC: a novel mode of kinase inhibitor resistance. Leukemia. 2015;29:1763-70 pubmed publisher |
- western blot; human; 1:850
| Higa-Nakamine S, Maeda N, Toku S, Yamamoto H. Involvement of Protein Kinase D1 in Signal Transduction from the Protein Kinase C Pathway to the Tyrosine Kinase Pathway in Response to Gonadotropin-releasing Hormone. J Biol Chem. 2015;290:25974-85 pubmed publisher |
- western blot; mouse; 1:1000; fig 1
| Robertson J, Jacquemet G, Byron A, Jones M, Warwood S, Selley J, et al. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling. Nat Commun. 2015;6:6265 pubmed publisher |
| Grossman H, Chuderland D, Ninio-Many L, Hasky N, Kaplan-Kraicer R, Shalgi R. A novel regulatory pathway in granulosa cells, the LH/human chorionic gonadotropin-microRNA-125a-3p-Fyn pathway, is required for ovulation. FASEB J. 2015;29:3206-16 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Yang F, Yu X, Liu C, Qu C, Gong Z, Liu H, et al. Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. Nat Commun. 2015;6:8202 pubmed publisher |
| Chien P, Lin C, Hsiao L, Yang C. c-Src/Pyk2/EGFR/PI3K/Akt/CREB-activated pathway contributes to human cardiomyocyte hypertrophy: Role of COX-2 induction. Mol Cell Endocrinol. 2015;409:59-72 pubmed publisher |
| Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher |
| Son J, Jeong H, Kim H, Kim Y, Lee E, Lee H, et al. Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase. Biochem Pharmacol. 2014;89:236-45 pubmed publisher |
- immunocytochemistry; mouse; 1:200; fig 5
| Kupferman J, Basu J, Russo M, Guevarra J, Cheung S, Siegelbaum S. Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment. Cell. 2014;158:1335-47 pubmed publisher |
| Liu L, Wen Q, Gong R, Gilles L, Stankiewicz M, Guo M, et al. PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN. Cell Death Dis. 2014;5:e988 pubmed publisher |
| Linch M, Sanz-García M, Rosse C, Riou P, Peel N, Madsen C, et al. Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. Carcinogenesis. 2014;35:396-406 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
- western blot; mouse
- immunocytochemistry; mouse
| Aguilera K, Rivera L, Hur H, Carbon J, Toombs J, Goldstein C, et al. Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma. Cancer Res. 2014;74:1032-44 pubmed publisher |
- western blot; human; 1:1000
| Henderson Y, Toro-Serra R, Chen Y, Ryu J, Frederick M, Zhou G, et al. Src inhibitors in suppression of papillary thyroid carcinoma growth. Head Neck. 2014;36:375-84 pubmed publisher |
| Glinskii O, Li F, Wilson L, Barnes S, Rittenhouse-Olson K, Barchi J, et al. Endothelial integrin α3β1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane. Oncotarget. 2014;5:1382-9 pubmed |
- western blot; human; 1:1000
| Burger K, Learman B, Boucherle A, Sirintrapun S, Isom S, Diaz B, et al. Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cells. Prostate. 2014;74:134-48 pubmed publisher |
- immunocytochemistry; human
| Iwata M, Torok-Storb B, Wayner E, Carter W. CDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production. PLoS ONE. 2014;9:e109304 pubmed publisher |
- western blot; African green monkey
| Kobayashi H, Saito T, Sato K, Furusawa K, Hosokawa T, Tsutsumi K, et al. Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5. J Biol Chem. 2014;289:19627-36 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100
| Cordero J, Ridgway R, Valeri N, Nixon C, Frame M, Muller W, et al. c-Src drives intestinal regeneration and transformation. EMBO J. 2014;33:1474-91 pubmed publisher |
| Yousuf S, Duan M, Moen E, Cross-Knorr S, Brilliant K, Bonavida B, et al. Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer. PLoS ONE. 2014;9:e92478 pubmed publisher |
| Czaplinska D, Turczyk L, Grudowska A, Mieszkowska M, Lipinska A, Skladanowski A, et al. Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration. Biochim Biophys Acta. 2014;1843:2461-70 pubmed publisher |
| Guerrouahen B, Pasquier J, Kaoud N, Maleki M, Beauchamp M, Yasmeen A, et al. Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer. Mol Cancer Ther. 2014;13:3123-36 pubmed publisher |
- immunohistochemistry; mouse; 1:100; fig 1
| DelGiorno K, Hall J, Takeuchi K, Pan F, Halbrook C, Washington M, et al. Identification and manipulation of biliary metaplasia in pancreatic tumors. Gastroenterology. 2014;146:233-44.e5 pubmed publisher |
| Paugh B, Zhu X, Qu C, Endersby R, Diaz A, Zhang J, et al. Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res. 2013;73:6219-29 pubmed publisher |
| Thompson W, Guilluy C, Xie Z, Sen B, Brobst K, Yen S, et al. Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells. Stem Cells. 2013;31:2528-37 pubmed publisher |
- western blot; human; 1:1000
| Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz-Van de Leur H, et al. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells. Oncogene. 2013;32:3587-97 pubmed publisher |
- chromatin immunoprecipitation; human
- western blot; human
| Muppala S, Mudduluru G, Leupold J, Buergy D, Sleeman J, Allgayer H. CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a. PLoS ONE. 2013;8:e59563 pubmed publisher |
- western blot; human; 1:1000
| Eckert M, Lwin T, Chang A, Kim J, Danis E, Ohno-Machado L, et al. Twist1-induced invadopodia formation promotes tumor metastasis. Cancer Cell. 2011;19:372-86 pubmed publisher |
| Kuboyama K, Fujikawa A, Masumura M, Suzuki R, Matsumoto M, Noda M. Protein tyrosine phosphatase receptor type z negatively regulates oligodendrocyte differentiation and myelination. PLoS ONE. 2012;7:e48797 pubmed publisher |
| Xiao J, Xu M, Hou T, Huang Y, Yang C, Li J. Dasatinib enhances antitumor activity of paclitaxel in ovarian cancer through Src signaling. Mol Med Rep. 2015;12:3249-56 pubmed publisher |
| Huber R, Lucas J, Gomez-Sarosi L, Coleman I, Zhao S, Coleman R, et al. DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance. Oncotarget. 2015;6:2134-47 pubmed |
| Hui E, Vale R. In vitro membrane reconstitution of the T-cell receptor proximal signaling network. Nat Struct Mol Biol. 2014;21:133-42 pubmed publisher |
| Gemel J, Levy A, Simon A, Bennett K, Ai X, AKHTER S, et al. Connexin40 abnormalities and atrial fibrillation in the human heart. J Mol Cell Cardiol. 2014;76:159-68 pubmed publisher |
| Kundumani-Sridharan V, Dyukova E, Hansen D, Rao G. 12/15-Lipoxygenase mediates high-fat diet-induced endothelial tight junction disruption and monocyte transmigration: a new role for 15(S)-hydroxyeicosatetraenoic acid in endothelial cell dysfunction. J Biol Chem. 2013;288:15830-42 pubmed publisher |
| Harr M, Caimi P, McColl K, Zhong F, Patel S, Barr P, et al. Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia. Cell Death Differ. 2010;17:1381-91 pubmed publisher |
| Nikolic D, Lehmann M, Felts R, Garcia E, Blanchet F, Subramaniam S, et al. HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation. Blood. 2011;118:4841-52 pubmed publisher |
| Wheeler S, Siwak D, Chai R, Lavalle C, Seethala R, Wang L, et al. Tumor epidermal growth factor receptor and EGFR PY1068 are independent prognostic indicators for head and neck squamous cell carcinoma. Clin Cancer Res. 2012;18:2278-89 pubmed publisher |
| Weber C, Schreiber T, Daub H. Dual phosphoproteomics and chemical proteomics analysis of erlotinib and gefitinib interference in acute myeloid leukemia cells. J Proteomics. 2012;75:1343-56 pubmed publisher |
| Zaytseva Y, Rychahou P, Gulhati P, Elliott V, Mustain W, O'Connor K, et al. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012;72:1504-17 pubmed publisher |
| Wheldon L, Haines B, Rajappa R, Mason I, Rigby P, Heath J. Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling. PLoS ONE. 2010;5:e10264 pubmed publisher |
