Phospho-IKKα (Ser176)/IKKβ (Ser177) (C84E11) Rabbit mAb | Cell Signaling Technology 2078S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-IKKα (Ser176)/IKKβ (Ser177) (C84E11) Rabbit mAb

catalog :

2078S

quantity :

100 ul

price :

274 USD

clonality :

monoclonal

host :

rabbit

antigen modification :

phosphorylated

reactivity :

human, mouse, rat, cow

application :

western blot

more info or order :

Cell Signaling Technology product webpage

citations: 10

Published Application/Species/Dilution	Reference
western blot; human	Wu N, Huang D, Tsou H, Lin Y, Lin W. Syk mediates IL-17-induced CCL20 expression by targeting Act1-dependent K63-linked ubiquitination of TRAF6. J Invest Dermatol. 2015;135:490-8 pubmed publisher
western blot; human; fig f4	Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed
western blot; human; fig s1 western blot; mouse; fig 1	Chen I, Hsu P, Hsu W, Chen N, Tseng P. Polyubiquitination of Transforming Growth Factor β-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4-mediated JNK and p38 MAPK Activation. Sci Rep. 2015;5:12300 pubmed publisher
western blot; human; fig 2	Wu Z, Wang C, Bai M, Li X, Mei Q, Li X, et al. An LRP16-containing preassembly complex contributes to NF-κB activation induced by DNA double-strand breaks. Nucleic Acids Res. 2015;43:3167-79 pubmed publisher
western blot; human	Cheng J, Fan Y, Xu X, Dou J, Tang Y, Zhong X, et al. A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways. Cell Death Dis. 2014;5:e1079 pubmed publisher
western blot; human	Journo C, Bonnet A, Favre-Bonvin A, Turpin J, Vinera J, Côté E, et al. Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO. J Virol. 2013;87:1123-36 pubmed publisher
western blot; human	Lecat A, Di Valentin E, Somja J, Jourdan S, Fillet M, Kufer T, et al. The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process. J Biol Chem. 2012;287:29213-26 pubmed publisher
	Fan Y, Mao R, Yu Y, Liu S, Shi Z, Cheng J, et al. USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase. J Exp Med. 2014;211:313-28 pubmed publisher
	Hosokawa J, Suzuki K, Nakagomi D, Tamachi T, Takatori H, Suto A, et al. Role of calcium ionophore A23187-induced activation of IkappaB kinase 2 in mast cells. Int Arch Allergy Immunol. 2013;161:37-43 pubmed publisher
	Sarkar S, Han J, Sinsimer K, Liao B, Foster R, Brewer G, et al. RNA-binding protein AUF1 regulates lipopolysaccharide-induced IL10 expression by activating IkappaB kinase complex in monocytes. Mol Cell Biol. 2011;31:602-15 pubmed publisher

product information

SKU :

2078S

Product-Name :

Phospho-IKKα (Ser176)/IKKβ (Ser177) (C84E11) Rabbit mAb

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M, (R, Mk, B)

Applications :

Western blot

Product-Category :

Immunology and Inflammation

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

85 (IKKalpha), 87 (IKKbeta)

Host :

Rabbit

Target :

IKK-alpha( Ser176)/IKK-beta (Ser177) phosphate

Primary-Protein :

IKK-alpha

Alt-Names :

CHUK,Conserved helix-loop-helix ubiquitous kinase,I-kappa-B kinase 1,I-kappa-B kinase alpha,I-kappa-B kinase-alpha,IKK-A,IKK-a kinase,IKK-alpha,IKK1,IKKA,IkB kinase alpha subunit,IkBKA,IkappaB kinase,Inhibitor of nuclear factor kappa-B kinase subunit alpha,NFKBIKA,Nuclear factor NF-kappa-B inhibitor kinase alpha,Nuclear factor NFkappaB inhibitor kinase alpha,TCF-16,TCF16,Transcription factor 16,conserved helix-loop ubiquitous kinase

more info or order :

Cell Signaling Technology product webpage