product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Histone Deacetylase 4 (HDAC4) Antibody
catalog :
2072
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; fig 6a
  • chromatin immunoprecipitation; mouse; loading ...; fig 6b
  • western blot; mouse; loading ...; fig s8c
Wang W, Song B, Anbarchian T, Shirazyan A, Sadik J, Lyons K. Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet. 2016;12:e1006352 pubmed publisher
  • western blot; rat; fig 8b
Smith C, D Mello S. Cell and Context-Dependent Effects of the Heat Shock Protein DNAJB6 on Neuronal Survival. Mol Neurobiol. 2016;53:5628-39 pubmed publisher
  • immunohistochemistry; rat; fig 2
  • western blot; rat; fig 1
Laumet G, Garriga J, Chen S, Zhang Y, Li D, Smith T, et al. G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition. Nat Neurosci. 2015;18:1746-55 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 4
  • western blot; mouse; fig 4
Rokach O, Sekulic Jablanovic M, Voermans N, Wilmshurst J, Pillay K, Heytens L, et al. Epigenetic changes as a common trigger of muscle weakness in congenital myopathies. Hum Mol Genet. 2015;24:4636-47 pubmed publisher
Liu J, Li Q, Wang X, Zhang C, Duan Y, Wang Z, et al. ?-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy. Cell Death Dis. 2016;7:e2183 pubmed publisher
Yao L, Wan J, Li H, Ding J, Wang Y, Wang X, et al. Resveratrol relieves gestational diabetes mellitus in mice through activating AMPK. Reprod Biol Endocrinol. 2015;13:118 pubmed publisher
King I, Yartseva V, Salas D, Kumar A, Heidersbach A, Ando D, et al. The RNA-binding protein TDP-43 selectively disrupts microRNA-1/206 incorporation into the RNA-induced silencing complex. J Biol Chem. 2014;289:14263-71 pubmed publisher
Prévilon M, Pezet M, Vinet L, Mercadier J, Rouet Benzineb P. Gender-specific potential inhibitory role of Ca2+/calmodulin dependent protein kinase phosphatase (CaMKP) in pressure-overloaded mouse heart. PLoS ONE. 2014;9:e90822 pubmed publisher
Wang G, He J, Zhao J, Yun W, Xie C, Taub J, et al. Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer. PLoS ONE. 2012;7:e52095 pubmed publisher
Raychaudhuri S. MicroRNAs overexpressed in growth-restricted rat skeletal muscles regulate the glucose transport in cell culture targeting central TGF-β factor SMAD4. PLoS ONE. 2012;7:e34596 pubmed publisher
Koizume S, Ito S, Miyagi E, Hirahara F, Nakamura Y, Sakuma Y, et al. HIF2?-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Res. 2012;40:5389-401 pubmed publisher
Zhang Z, Cai Y, Zou F, Bie B, Pan Z. Epigenetic suppression of GAD65 expression mediates persistent pain. Nat Med. 2011;17:1448-55 pubmed publisher
Rajendran P, Delage B, Dashwood W, Yu T, Wuth B, Williams D, et al. Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly. Mol Cancer. 2011;10:68 pubmed publisher
Xu X, Xie C, Edwards H, Zhou H, Buck S, Ge Y. Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells. PLoS ONE. 2011;6:e17138 pubmed publisher
Rajan I, Savelieva K, Ye G, Wang C, Malbari M, Friddle C, et al. Loss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone development. PLoS ONE. 2009;4:e6612 pubmed publisher
Kajiwara Y, Akram A, Katsel P, Haroutunian V, Schmeidler J, Beecham G, et al. FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4. PLoS ONE. 2009;4:e5071 pubmed publisher
product information
SKU :
2072S
Product-Name :
Histone Deacetylase 4 (HDAC4) Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
140
Host :
Rabbit
Target :
HDAC4
Primary-Protein :
HDAC4
Alt-Names :
HA6116,HD4,HDAC-A,HDAC4,HDACA,Histone deacetylase 4,KIAA0288,histone deacetylase A
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.