product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Histone Deacetylase 1 (HDAC1) Antibody
catalog :
2062
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, chromatin immunoprecipitation
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4
Liu Z, Lam N, Wang E, Virden R, Pawel B, Attiyeh E, et al. Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma. Oncogene. 2017;36:97-109 pubmed publisher
  • western blot; mouse; loading ...; fig 2b
El Hokayem J, Brittain G, Nawaz Z, Bethea J. Tumor Necrosis Factor Receptor Associated Factors (TRAFs) 2 and 3 Form a Transcriptional Complex with Phosho-RNA Polymerase II and p65 in CD40 Ligand Activated Neuro2a Cells. Mol Neurobiol. 2017;54:1301-1313 pubmed publisher
  • western blot; human; fig 1s1
Mounir Z, Korn J, Westerling T, Lin F, Kirby C, Schirle M, et al. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor. elife. 2016;5: pubmed publisher
  • western blot; human; fig 1
Bleckmann A, Conradi L, Menck K, Schmick N, Schubert A, Rietkötter E, et al. β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases. Clin Exp Metastasis. 2016;33:309-23 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, et al. BAX inhibitor-1 is a Ca(2+) channel critically important for immune cell function and survival. Cell Death Differ. 2016;23:358-68 pubmed publisher
  • western blot; mouse; 1:1000; fig 6a
Mazur P, Herner A, Mello S, Wirth M, Hausmann S, Sánchez Rivera F, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med. 2015;21:1163-71 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5b
Moussa R, Kovacevic Z, Richardson D. Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types. Oncotarget. 2015;6:29694-711 pubmed publisher
  • western blot; mouse; fig 5
Mani S, Kern C, Kimbrough D, Addy B, Kasiganesan H, Rivers W, et al. Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction. Am J Physiol Heart Circ Physiol. 2015;308:H1391-401 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 3b
Flowers S, Beck G, Moran E. Tissue-specific gene targeting by the multiprotein mammalian DREAM complex. J Biol Chem. 2011;286:27867-71 pubmed publisher
Das S, Jackson W, Prasain J, Hanna A, Bailey S, Tucker J, et al. Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. Sci Rep. 2017;7:40773 pubmed publisher
Wu C, Zhang H, Gupta N, Alshareef A, Wang Q, Huang Y, et al. A positive feedback loop involving the Wnt/?-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma. J Hematol Oncol. 2016;9:120 pubmed
Nakshatri H, Appaiah H, Anjanappa M, Gilley D, Tanaka H, Badve S, et al. NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT. Cell Death Dis. 2015;6:e1608 pubmed publisher
Kim J, Jee B, Lee J, Suh C, Kim S. Histone acetylation level and histone acetyltransferase/deacetylase activity in ejaculated sperm from normozoospermic men. Yonsei Med J. 2014;55:1333-40 pubmed publisher
Wang G, He J, Zhao J, Yun W, Xie C, Taub J, et al. Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer. PLoS ONE. 2012;7:e52095 pubmed publisher
De Wever V, Lloyd D, Nasa I, Nimick M, Trinkle Mulcahy L, Gourlay R, et al. Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21. PLoS ONE. 2012;7:e39510 pubmed publisher
Das S, Tucker J, Khullar S, Samant R, Shevde L. Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases. PLoS ONE. 2012;7:e34374 pubmed publisher
Zhang Z, Cai Y, Zou F, Bie B, Pan Z. Epigenetic suppression of GAD65 expression mediates persistent pain. Nat Med. 2011;17:1448-55 pubmed publisher
Xu X, Xie C, Edwards H, Zhou H, Buck S, Ge Y. Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells. PLoS ONE. 2011;6:e17138 pubmed publisher
Flowers S, Nagl N, Beck G, Moran E. Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation. J Biol Chem. 2009;284:10067-75 pubmed publisher
product information
SKU :
2062S
Product-Name :
Histone Deacetylase 1 (HDAC1) Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
62
Host :
Rabbit
Target :
HDAC1
Primary-Protein :
HDAC1
Alt-Names :
DKFZp686H12203,GON-10,HD1,HDAC1,Histone deacetylase 1,RPD3,RPD3L1,reduced potassium dependency, yeast homolog-like 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.