product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-PKD/PKCμ (Ser744/748) Antibody
catalog :
2054
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 1
Xiong J, Zhou M, Wang Y, Chen L, Xu W, Wang Y, et al. Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice. Sci Rep. 2016;6:34079 pubmed publisher
  • immunoprecipitation; human
  • western blot; human; 1:850
Higa Nakamine S, Maeda N, Toku S, Yamamoto H. Involvement of Protein Kinase D1 in Signal Transduction from the Protein Kinase C Pathway to the Tyrosine Kinase Pathway in Response to Gonadotropin-releasing Hormone. J Biol Chem. 2015;290:25974-85 pubmed publisher
  • western blot; human; loading ...; fig 1g
Cho Y, Park D, Cavalli V. Filamin A is required in injured axons for HDAC5 activity and axon regeneration. J Biol Chem. 2015;290:22759-70 pubmed publisher
  • western blot; mouse; fig 1
Müller M, Schröer J, Azoitei N, Eiseler T, Bergmann W, Köhntop R, et al. A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells. Sci Rep. 2015;5:11742 pubmed publisher
  • western blot; mouse
Ackerknecht M, Hauser M, Legler D, Stein J. In vivo TCR Signaling in CD4(+) T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity. Front Immunol. 2015;6:297 pubmed publisher
  • western blot; mouse
Chakraborty A, Pasek D, Huang T, Gomez A, Yamaguchi N, Anderson M, et al. Inhibition of CaMKII does not attenuate cardiac hypertrophy in mice with dysfunctional ryanodine receptor. PLoS ONE. 2014;9:e104338 pubmed publisher
  • western blot; human
Wang N, Su P, Zhang Y, Lu J, Xing B, Kang K, et al. Protein kinase D1-dependent phosphorylation of dopamine D1 receptor regulates cocaine-induced behavioral responses. Neuropsychopharmacology. 2014;39:1290-301 pubmed publisher
  • western blot; human
Coria A, Masseroni M, Díaz Añel A. Regulation of PKD1-mediated Golgi to cell surface trafficking by G?q subunits. Biol Cell. 2014;106:30-43 pubmed publisher
  • western blot; human
  • western blot; chicken
Moreno Garcia M, Sommer K, Rincón Arano H, Brault M, Ninomiya Tsuji J, Matesic L, et al. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-?B activation. Mol Cell Biol. 2013;33:1149-63 pubmed publisher
  • immunohistochemistry; rat; 1:100
  • immunocytochemistry; human; 1:200
  • western blot; human; 1:1000
  • immunohistochemistry; mouse; 1:100
Amadesi S, Grant A, Cottrell G, Vaksman N, Poole D, Rozengurt E, et al. Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2. J Comp Neurol. 2009;516:141-56 pubmed publisher
Chang J, Ni Y, Han L, Sinnett Smith J, Jacamo R, Rey O, et al. Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization. J Biol Chem. 2017;292:9523-9539 pubmed publisher
Leung A, Backstrom I, Bally M. Sulfonation, an underexploited area: from skeletal development to infectious diseases and cancer. Oncotarget. 2016;7:55811-55827 pubmed publisher
Karvela M, Baquero P, Kuntz E, Mukhopadhyay A, Mitchell R, Allan E, et al. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016;12:936-48 pubmed publisher
Torres Ayuso P, Tello Lafoz M, Mérida I, Ávila Flores A. Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1. Oncogenesis. 2015;4:e164 pubmed publisher
Arun S, Kaddour Djebbar I, Shapiro B, Bollag W. Ultraviolet B irradiation and activation of protein kinase D in primary mouse epidermal keratinocytes. Oncogene. 2011;30:1586-96 pubmed publisher
Bredemeyer A, Helmink B, Innes C, Calderon B, McGinnis L, Mahowald G, et al. DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes. Nature. 2008;456:819-23 pubmed publisher
product information
SKU :
2054S
Product-Name :
Phospho-PKD/PKCμ (Ser744/748) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Ca, cAMP and Lipid Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
115
Host :
Rabbit
Target :
PKD1 (PKCmu) (Ser738/Ser742) phosphate
Primary-Protein :
PKD1
Alt-Names :
KPCD1,PKC-MU,PKCM,PKD,PKD1,PRKCM,PRKD1,Protein kinase C mu type,Protein kinase D,Serine/threonine-protein kinase D1,nPKC-D1,nPKC-mu,protein kinase C, mu,protein kinase D1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.