product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CENP-A (C51A7) Rabbit mAb (Mouse Specific; IF Preferred)
catalog :
2048
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C51A7
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; fig 2a
Lau E, Damiani D, Chehade G, Ruiz Reig N, Saade R, Jossin Y, et al. DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction. elife. 2021;10: pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s3b
Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard Levin Z, et al. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev. 2017;31:463-480 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s4i
Malek Mohammadi M, Kattih B, Grund A, Froese N, Korf Klingebiel M, Gigina A, et al. The transcription factor GATA4 promotes myocardial regeneration in neonatal mice. EMBO Mol Med. 2017;9:265-279 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 5a
Biswas U, Hempel K, Llano E, Pendas A, Jessberger R. Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis. PLoS Genet. 2016;12:e1006389 pubmed publisher
  • immunohistochemistry; mouse; 1:50; fig 3
Guzman Ayala M, Sachs M, Koh F, Onodera C, Bulut Karslioglu A, Lin C, et al. Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast. Development. 2015;142:118-27 pubmed publisher
  • immunocytochemistry; mouse; fig s8
Flach J, Bakker S, Mohrin M, Conroy P, Pietras E, Reynaud D, et al. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 2014;512:198-202 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse; fig 3
Luebben S, Kawabata T, Akre M, Lee W, Johnson C, O Sullivan M, et al. Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res. 2013;41:10283-97 pubmed publisher
Baumann C, Zhang X, Viveiros M, De La Fuente R. Pericentric major satellite transcription is essential for meiotic chromosome stability and spindle pole organization. Open Biol. 2023;13:230133 pubmed publisher
Swartz S, McKay L, Su K, Bury L, Padeganeh A, Maddox P, et al. Quiescent Cells Actively Replenish CENP-A Nucleosomes to Maintain Centromere Identity and Proliferative Potential. Dev Cell. 2019;51:35-48.e7 pubmed publisher
Nakazawa N, Sathe A, Shivashankar G, Sheetz M. Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression. Proc Natl Acad Sci U S A. 2016;113:E6813-E6822 pubmed
Dambacher S, Deng W, Hahn M, Sadic D, Frohlich J, Nuber A, et al. CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin. Nucleus. 2012;3:101-10 pubmed publisher
Lee S, Itkin Ansari P, Levine F. CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells. Aging (Albany NY). 2010;2:785-90 pubmed
product information
SKU :
2048S
Product-Name :
CENP-A (C51A7) Rabbit mAb (Mouse Specific; IF Preferred)
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
M
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
17
Host :
Rabbit
Target :
CENPA mouse
Primary-Protein :
CENPA
Alt-Names :
CENP-A,Cenpa,Centromere protein A,Histone H3-like centromeric protein A,OTTMUSP00000025185,centromere autoantigen A,centrosomin A
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.