product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PP2A A Subunit (81G5) Rabbit mAb
catalog :
2041
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
81G5
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 7a
  • western blot; mouse; fig 6e
Xiao G, Chan L, Klemm L, Braas D, Chen Z, Geng H, et al. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018;173:470-484.e18 pubmed publisher
  • western blot; human; loading ...; fig s11e
Sangodkar J, Perl A, Tohme R, Kiselar J, Kastrinsky D, Zaware N, et al. Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth. J Clin Invest. 2017;127:2081-2090 pubmed publisher
  • western blot; human; loading ...; fig 1c
Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, et al. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun. 2016;7:12431 pubmed publisher
  • western blot; human; 1:1000; fig 6
  • western blot; mouse; 1:1000; fig s3
Wong P, Feng Y, Wang J, Shi R, Jiang X. Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun. 2015;6:8048 pubmed publisher
  • western blot; human; 1:1000; fig s7
  • immunocytochemistry; mouse; 1:100; fig 2
  • western blot; mouse; 1:1000; fig 3
Yu C, Ji S, Sha Q, Sun Q, Fan H. CRL4-DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation. Nat Commun. 2015;6:8017 pubmed publisher
Pandey P, Seshacharyulu P, Das S, Rachagani S, Ponnusamy M, Yan Y, et al. Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway. Br J Cancer. 2013;108:2590-600 pubmed publisher
Haaß W, Stehle M, Nittka S, Giehl M, Schrotz King P, Fabarius A, et al. The proteolytic activity of separase in BCR-ABL-positive cells is increased by imatinib. PLoS ONE. 2012;7:e42863 pubmed publisher
product information
SKU :
2041S
Product-Name :
PP2A A Subunit (81G5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
62
Host :
Rabbit
Target :
PP2A A subunit
Primary-Protein :
PPP2R1A
Alt-Names :
2AAA,MGC786,Medium tumor antigen-associated 61 kDa protein,PP2A subunit A isoform PR65-alpha,PP2A subunit A isoform R1-alpha,PP2A-Aalpha,PP2AAALPHA,PPP2R1A,PR65A,Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform,protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform,protein phosphatase 2, regulatory subunit A, alpha,serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.