| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; fig 5c
| Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang C, et al. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. Nat Commun. 2021;12:5321 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4a
| Zhou L, Nho K, Haddad M, Cherepacha N, Tubeleviciute Aydin A, Tsai A, et al. Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration. Sci Rep. 2021;11:12695 pubmed publisher |
- western blot; human; fig 1h
| Andrade J, Shi C, Costa A, Choi J, Kim J, Doddaballapur A, et al. Control of endothelial quiescence by FOXO-regulated metabolites. Nat Cell Biol. 2021;23:413-423 pubmed publisher |
- western blot; mouse; loading ...; fig 3f
| Valbuena Perez J, Linnenberger R, Dembek A, Bruscoli S, Riccardi C, Schulz M, et al. Altered glucocorticoid metabolism represents a feature of macroph-aging. Aging Cell. 2020;19:e13156 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1g
| Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, et al. Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020;11:859 pubmed publisher |
- immunohistochemistry; human; 1:1000; loading ...
| Nihei Y, Mori K, Werner G, Arzberger T, Zhou Q, Khosravi B, et al. Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. Acta Neuropathol. 2020;139:99-118 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s1b
| James C, Müller M, Goldberg M, Lenz C, Urlaub H, Kehlenbach R. Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane. J Biol Chem. 2019;294:16241-16254 pubmed publisher |
- western blot; mouse; fig 4a
| Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s1b
| Halfmann C, Sears R, Katiyar A, Busselman B, Aman L, Zhang Q, et al. Repair of nuclear ruptures requires barrier-to-autointegration factor. J Cell Biol. 2019;: pubmed publisher |
- western blot; mouse; loading ...; fig s2a
| Guo M, Hartlova A, Gierlinski M, Prescott A, Castellvi J, Losa J, et al. Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages. EMBO J. 2019;38: pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 6b
| Brody M, Vanhoutte D, Bakshi C, Liu R, Correll R, Sargent M, et al. Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis. J Biol Chem. 2019;294:8918-8929 pubmed publisher |
- western blot; mouse; loading ...; fig 1d
| Shang X, Shen C, Liu J, Tang L, Zhang H, Wang Y, et al. Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm-egg binding. Cell Mol Life Sci. 2018;75:4371-4384 pubmed publisher |
- western blot; mouse; loading ...; fig s15a
| Wang P, Xu J, Wang Y, Cao X. An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism. Science. 2017;358:1051-1055 pubmed publisher |
- western blot; mouse; loading ...; fig 2f
| Huh H, Lee E, Shin J, Park B, Lee S. STRAP positively regulates TLR3-triggered signaling pathway. Cell Immunol. 2017;318:55-60 pubmed publisher |
- immunoprecipitation; human; loading ...; fig 5a
| Barilari M, Bonfils G, Treins C, Koka V, De Villeneuve D, Fabrega S, et al. ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J. 2017;36:736-750 pubmed publisher |
- western blot; mouse; fig 2d
| Mooney C, Jimenez Mateos E, Engel T, Mooney C, Diviney M, Venø M, et al. RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Sci Rep. 2017;7:41517 pubmed publisher |
- western blot; human; loading ...; fig 2e
| Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed publisher |
- western blot; mouse; loading ...; fig 2g
| Huh H, Ra E, Lee T, Kang S, Park A, Lee E, et al. STRAP Acts as a Scaffolding Protein in Controlling the TLR2/4 Signaling Pathway. Sci Rep. 2016;6:38849 pubmed publisher |
- immunohistochemistry; mouse; fig 3
| Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Koike M, Uchiyama Y, et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep. 2016;6:34575 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 3b
| Blanco F, Preet R, Aguado A, Vishwakarma V, Stevens L, Vyas A, et al. Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. Oncotarget. 2016;7:74043-74058 pubmed publisher |
- immunohistochemistry; domestic rabbit; fig 4b
- western blot; domestic rabbit; fig 3a
| Wu A, Xu D, Yang N, Lin S, Chen P, Cala S, et al. Phospholamban is concentrated in the nuclear envelope of cardiomyocytes and involved in perinuclear/nuclear calcium handling. J Mol Cell Cardiol. 2016;100:1-8 pubmed publisher |
- western blot; rat; fig 3d
| Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed |
- western blot; human; fig 6
| Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed publisher |
- western blot; mouse; fig 2
| Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed publisher |
- immunocytochemistry; human; tbl 1
| Almeida C, Fernandes S, Ribeiro Junior A, Keith Okamoto O, Vainzof M. Muscle Satellite Cells: Exploring the Basic Biology to Rule Them. Stem Cells Int. 2016;2016:1078686 pubmed publisher |
- western blot; human; fig s5
| Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher |
- western blot; human; loading ...; fig 4c
| Stanford E, Wang Z, Novikov O, Mulas F, Landesman Bollag E, Monti S, et al. The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells. BMC Biol. 2016;14:20 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Cannavo A, Liccardo D, Eguchi A, Elliott K, Traynham C, Ibetti J, et al. Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun. 2016;7:10877 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| El Hokayem J, Brittain G, Nawaz Z, Bethea J. Tumor Necrosis Factor Receptor Associated Factors (TRAFs) 2 and 3 Form a Transcriptional Complex with Phosho-RNA Polymerase II and p65 in CD40 Ligand Activated Neuro2a Cells. Mol Neurobiol. 2017;54:1301-1313 pubmed publisher |
- western blot; human; fig 2
| Chen N, Chyau C, Lee Y, Tseng H, Chou F. Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells. Sci Rep. 2016;6:20417 pubmed publisher |
- western blot; human; fig 3
| Zhang G, Chan B, Samarina N, Abere B, Weidner Glunde M, Buch A, et al. Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Proc Natl Acad Sci U S A. 2016;113:E1034-43 pubmed publisher |
- western blot; mouse; fig 1
| Lagarrigue S, Lopez Mejia I, Denechaud P, Escoté X, Castillo Armengol J, Jimenez V, et al. CDK4 is an essential insulin effector in adipocytes. J Clin Invest. 2016;126:335-48 pubmed publisher |
| Softic S, Gupta M, Wang G, Fujisaka S, O Neill B, Rao T, et al. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J Clin Invest. 2017;127:4059-4074 pubmed publisher |
| Meng Z, Gong J, Chen Z, Sun J, Xiao Y, Wang L, et al. Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis. Mol Cell. 2017;66:332-344.e4 pubmed publisher |
| Marins F, Iddings J, Fontes M, Filosa J. Evidence that remodeling of insular cortex neurovascular unit contributes to hypertension-related sympathoexcitation. Physiol Rep. 2017;5: pubmed publisher |
| Lee E, Lee T, Kim J, Park A, Ra E, Kang S, et al. CNBP acts as a key transcriptional regulator of sustained expression of interleukin-6. Nucleic Acids Res. 2017;45:3280-3296 pubmed publisher |
| Nyati K, Masuda K, Zaman M, Dubey P, Millrine D, Chalise J, et al. TLR4-induced NF-?B and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a. Nucleic Acids Res. 2017;45:2687-2703 pubmed publisher |
| Smith E, Meng Y, Moore R, Tse J, Xu A, Xu X. Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression. BMC Cell Biol. 2017;18:8 pubmed publisher |
| Gaston J, Cheradame L, Yvonnet V, Déas O, Poupon M, Judde J, et al. Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents. Oncotarget. 2016;7:77205-77224 pubmed publisher |
| Fedoseienko A, Wieringa H, Wisman G, Duiker E, Reyners A, Hofker M, et al. Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer. PLoS ONE. 2016;11:e0165385 pubmed publisher |
| George C, Birnie M, Flynn B, Kershaw Y, Lightman S, Conway Campbell B. Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo. Mol Cell Endocrinol. 2017;439:46-53 pubmed publisher |
| Liu R, Khalil H, Lin S, Sargent M, York A, Molkentin J. Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart. PLoS ONE. 2016;11:e0164897 pubmed publisher |
| Seo H, Kim H, Kang M, Ryum J, Yi E, Cho J. Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation. Sci Rep. 2016;6:34614 pubmed publisher |
| Zhang J, Wang J, Xu J, Lu Y, Jiang J, Wang L, et al. Curcumin targets the TFEB-lysosome pathway for induction of autophagy. Oncotarget. 2016;7:75659-75671 pubmed publisher |
| Bouvier C, Macagno N, Nguyen Q, Loundou A, Jiguet Jiglaire C, Gentet J, et al. Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcoma. Oncotarget. 2016;7:64702-64710 pubmed publisher |
| Ahmed K, Kren B, Abedin M, Vogel R, Shaughnessy D, Nacusi L, et al. CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors. Oncotarget. 2016;7:61789-61805 pubmed publisher |
| Duffy D, Krstic A, Schwarzl T, Halasz M, Iljin K, Fey D, et al. Wnt signalling is a bi-directional vulnerability of cancer cells. Oncotarget. 2016;7:60310-60331 pubmed publisher |
| Cavadas M, Mesnieres M, Crifò B, Manresa M, Selfridge A, Keogh C, et al. REST is a hypoxia-responsive transcriptional repressor. Sci Rep. 2016;6:31355 pubmed publisher |
| Batalha V, Ferreira D, Coelho J, Valadas J, Gomes R, Temido Ferreira M, et al. The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. Sci Rep. 2016;6:31493 pubmed publisher |
| Nandakumar V, Hansen N, Glenn H, Han J, Helland S, Hernandez K, et al. Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells. Sci Rep. 2016;6:30593 pubmed publisher |
| Suyama K, Silagi E, Choi H, Sakabe K, Mochida J, Shapiro I, et al. Circadian factors BMAL1 and ROR? control HIF-1? transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget. 2016;7:23056-71 pubmed publisher |
| Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed |
| Liu S, Ge D, Chen L, Zhao J, Su L, Zhang S, et al. A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4. Oncotarget. 2016;7:16282-96 pubmed publisher |
| Maine E, Westcott J, Prechtl A, Dang T, Whitehurst A, Pearson G. The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion. Oncotarget. 2016;7:14708-26 pubmed publisher |
| Delmas E, Jah N, Pirou C, Bouleau S, Le Floch N, Vayssière J, et al. FGF1 C-terminal domain and phosphorylation regulate intracrine FGF1 signaling for its neurotrophic and anti-apoptotic activities. Cell Death Dis. 2016;7:e2079 pubmed publisher |
| Wang L, Xu W, Cao L, Tian T, Yang M, Li Z, et al. Differential Expression of Proteins Associated with the Hair Follicle Cycle - Proteomics and Bioinformatics Analyses. PLoS ONE. 2016;11:e0146791 pubmed publisher |
