product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Lamin A/C (Ser22) Antibody
catalog :
2026
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:200; loading ...; fig 6g
  • western blot; human; 1:1000; loading ...; fig 6h
Zhang Y, Wang J, Huang W, Cai J, Ba J, Wang Y, et al. Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation. Nat Commun. 2018;9:3613 pubmed publisher
  • western blot; human; loading ...; fig 4a
Wu S, Pan S, Zhang L, Baines J, Roller R, Ames J, et al. Herpes Simplex Virus 1 Induces Phosphorylation and Reorganization of Lamin A/C through the ?134.5 Protein That Facilitates Nuclear Egress. J Virol. 2016;90:10414-10422 pubmed
  • western blot; human; 1:1000; fig 9
Rasmussen M, Lyskjær I, Jersie Christensen R, Tarpgaard L, Primdal Bengtson B, Nielsen M, et al. miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. Nat Commun. 2016;7:12436 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 2
  • western blot; human; 1:1000; fig 2
Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed
  • western blot; human; 1:1000; fig 1
Moiseeva O, Lessard F, Acevedo Aquino M, Vernier M, Tsantrizos Y, Ferbeyre G. Mutant lamin A links prophase to a p53 independent senescence program. Cell Cycle. 2015;14:2408-21 pubmed publisher
  • western blot; human; fig 4
Wang Y, Yang Y, Wu S, Pan S, Zhou C, Ma Y, et al. p32 is a novel target for viral protein ICP34.5 of herpes simplex virus type 1 and facilitates viral nuclear egress. J Biol Chem. 2014;289:35795-805 pubmed publisher
Kuny C, Chinchilla K, Culbertson M, Kalejta R. Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinases. PLoS Pathog. 2010;6:e1001092 pubmed publisher
product information
SKU :
2026S
Product-Name :
Phospho-Lamin A/C (Ser22) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
69, 78
Host :
Rabbit
Target :
Lamin A/C (Ser22) phosphate
Primary-Protein :
lamin A/C
Alt-Names :
70 kDa lamin,CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,HGPS,IDC,LDP1,LFP,LGMD1B,LMN1,LMNA,LMNC,Lamin-A/C,PRO1,Renal carcinoma antigen NY-REN-32,lamin A/C
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.