product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
α-Smooth Muscle Actin
catalog :
19245
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D4K9N
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 7c
Li Y, Li Y, Li L, Yin M, Wang J, Li X. PKR deficiency alleviates pulmonary hypertension via inducing inflammasome adaptor ASC inactivation. Pulm Circ. 2021;11:20458940211046156 pubmed publisher
  • western blot; human; 1:1000
Mahata T, Sengar A, Basak M, Das K, Pramanick A, Verma S, et al. Hepatic Regulator of G Protein Signaling 6 (RGS6) drives non-alcoholic fatty liver disease by promoting oxidative stress and ATM-dependent cell death. Redox Biol. 2021;46:102105 pubmed publisher
  • western blot; human; loading ...; fig 2e
Sun Z, Sun D, Feng Y, Zhang B, Sun P, Zhou B, et al. Exosomal linc-ROR mediates crosstalk between cancer cells and adipocytes to promote tumor growth in pancreatic cancer. Mol Ther Nucleic Acids. 2021;26:253-268 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 4c
Yamamoto Y, Minami M, Yoshida K, Nagata M, Miyata T, Yang T, et al. Irradiation Accelerates Plaque Formation and Cellular Senescence in Flow-Altered Carotid Arteries of Apolipoprotein E Knock-Out Mice. J Am Heart Assoc. 2021;10:e020712 pubmed publisher
  • immunohistochemistry; rat; loading ...; fig 3a
Zou Z, Chai M, Guo F, Fu X, Lan Y, Cao S, et al. MicroRNA-126 engineered muscle-derived stem cells attenuates cavernosa injury-induced erectile dysfunction in rats. Aging (Albany NY). 2021;13:14399-14415 pubmed publisher
  • immunocytochemistry; mouse; fig 2g
  • western blot; mouse; 1:1000; fig 2f
Shen K, Li R, Zhang X, Qu G, Li R, Wang Y, et al. Acetyl oxygen benzoate engeletin ester promotes KLF4 degradation leading to the attenuation of pulmonary fibrosis via inhibiting TGFβ1-smad/p38MAPK-lnc865/lnc556-miR-29b-2-5p-STAT3 signal pathway. Aging (Albany NY). 2021;13:13807-13821 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1d, 1f, s4a
Ni N, Fang X, Li Q. Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract. Sci Rep. 2021;11:9294 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4e
Wang X, Fu Y, Xie Z, Cao M, Qu W, Xi X, et al. Establishment of a Novel Mouse Model for Atherosclerotic Vulnerable Plaque. Front Cardiovasc Med. 2021;8:642751 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 3a
Sun Q, Chen J, Xu L, Kang J, Wu X, Ren Y, et al. MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model. Oxid Med Cell Longev. 2020;2020:4828256 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3f
Reventun P, Sanchez Esteban S, Cook A, Cuadrado I, Roza C, Moreno Gómez Toledano R, et al. Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway. Sci Rep. 2020;10:4190 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3b
Gallo S, Spilinga M, Albano R, Ferrauto G, Di Gregorio E, Casanova E, et al. Activation of the MET receptor attenuates doxorubicin-induced cardiotoxicity in vivo and in vitro. Br J Pharmacol. 2020;177:3107-3122 pubmed publisher
  • western blot; human; loading ...; fig 4c
  • immunohistochemistry; mouse; loading ...; fig 1c
Fu X, Qie J, Fu Q, Chen J, Jin Y, Ding Z. miR-20a-5p/TGFBR2 Axis Affects Pro-inflammatory Macrophages and Aggravates Liver Fibrosis. Front Oncol. 2020;10:107 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:640; loading ...; fig 5g
Chung K, Hsu C, Fan L, Huang Z, Bhatia D, Chen Y, et al. Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis. Nat Commun. 2019;10:3390 pubmed publisher
  • western blot; mouse; loading ...; fig 2e
Huang X, Xue H, Ma J, Zhang Y, Zhang J, Liu Y, et al. Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β-catenin activity. J Cell Mol Med. 2019;23:4443-4453 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 3e, 3f
Li Y, Lu Y, Chen Y. Long non-coding RNA SNHG16 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer via sponging miR-200a-3p. Biosci Rep. 2019;39: pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.