product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Flotillin-1 (D2V7J) XP Rabbit mAb
catalog :
18634
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D2V7J
reactivity :
human, mouse
application :
western blot, immunocytochemistry, western blot knockout validation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:1000; loading ...; fig 7a
  • immunocytochemistry; human; 1:1000; loading ...; fig 2a
Brandel A, Aigal S, Lagies S, Schlimpert M, Meléndez A, Xu M, et al. The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa. Cell Mol Life Sci. 2021;78:3637-3656 pubmed publisher
  • western blot; mouse; loading ...
Gan L, Liu D, Liu J, Chen E, Chen C, Liu L, et al. CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice. Signal Transduct Target Ther. 2021;6:223 pubmed publisher
  • western blot; human; loading ...; fig 1e, 1h
Fu C, Zhang Q, Wang A, Yang S, Jiang Y, Bai L, et al. EWI-2 controls nucleocytoplasmic shuttling of EGFR signaling molecules and miRNA sorting in exosomes to inhibit prostate cancer cell metastasis. Mol Oncol. 2021;15:1543-1565 pubmed publisher
  • western blot; human; 1:1000; fig s2h
Bi J, Ichu T, Zanca C, Yang H, Zhang W, Gu Y, et al. Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling. Cell Metab. 2019;30:525-538.e8 pubmed publisher
  • western blot; human; loading ...; fig s5f
Murillo O, Thistlethwaite W, Rozowsky J, Subramanian S, Lucero R, Shah N, et al. exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids. Cell. 2019;177:463-477.e15 pubmed publisher
  • western blot; human; 1:1000; fig 3b
Pinet S, Bessette B, Vedrenne N, Lacroix A, Richard L, Jauberteau M, et al. TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells. Oncotarget. 2016;7:50349-50364 pubmed publisher
King K, Ghosh P, Wozniak A. TRIM25 dictates selective miRNA loading into extracellular vesicles during inflammation. Sci Rep. 2023;13:22952 pubmed publisher
Manners O, Baquero Perez B, Mottram T, Yonchev I, Trevelyan C, Harper K, et al. m6A Regulates the Stability of Cellular Transcripts Required for Efficient KSHV Lytic Replication. Viruses. 2023;15: pubmed publisher
Fleck A, Flotte A, Si E, Mu D. Loss of Gap Junction Factor Connexin 43 Results in an Increase of Exosomal Tetraspanins in Human Lung Cancer Cell Line A549. MicroPubl Biol. 2022;2022: pubmed publisher
van den Broek B, Wuyts C, Sisto A, Pintelon I, Timmermans J, Somers V, et al. Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles. Cell Commun Signal. 2022;20:58 pubmed publisher
Uygur B, Melikov K, Arakelyan A, Margolis L, Chernomordik L. Syncytin 1 dependent horizontal transfer of marker genes from retrovirally transduced cells. Sci Rep. 2019;9:17637 pubmed publisher
Wang S, Liu Z, Ye T, Mabrouk O, Maltbie T, Aasly J, et al. Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers. Acta Neuropathol Commun. 2017;5:86 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.