product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Bcl-2 (124) Mouse mAb
catalog :
15071
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
124
reactivity :
human, mouse, rat
application :
western blot
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 9a
Li K, Wu R, Zhou M, Tong H, Luo K. Desmosomal proteins of DSC2 and PKP1 promote cancer cells survival and metastasis by increasing cluster formation in circulatory system. Sci Adv. 2021;7:eabg7265 pubmed publisher
  • western blot; human; loading ...; fig 6f
Yan D, Li X, Yang Q, Huang Q, Yao L, Zhang P, et al. Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30. Cell Death Discov. 2021;7:211 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2c
Zhao Z, Szczepanski A, Tsuboyama N, Abdala Valencia H, Goo Y, Singer B, et al. PAX9 Determines Epigenetic State Transition and Cell Fate in Cancer. Cancer Res. 2021;81:4696-4708 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 2c
Meng L, Zhang Y, Li D, Shang X, Hao X, Chen X, et al. TIMP3 attenuates cerebral ischemia/reperfusion-induced apoptosis and oxidative stress in neurocytes by regulating the AKT pathway. Exp Ther Med. 2021;22:973 pubmed publisher
  • western blot; human; loading ...; fig 3c
Lee S, Jung J, Lee Y, Kim S, Kim J, Kim B, et al. Targeting HSF1 as a Therapeutic Strategy for Multiple Mechanisms of EGFR Inhibitor Resistance in EGFR Mutant Non-Small-Cell Lung Cancer. Cancers (Basel). 2021;13: pubmed publisher
  • western blot; human; loading ...; fig 4a
Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, et al. IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation. Nat Commun. 2021;12:3651 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7d
Li Q, Liu M, Sun Y, Jin T, Zhu P, Wan X, et al. SLC6A8-mediated intracellular creatine accumulation enhances hypoxic breast cancer cell survival via ameliorating oxidative stress. J Exp Clin Cancer Res. 2021;40:168 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4g
  • western blot; mouse; loading ...; fig 4h
Nishad R, Mukhi D, Singh A, Motrapu M, Chintala K, Tammineni P, et al. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021;12:342 pubmed publisher
  • western blot; human; loading ...; fig 4f
Yin S, Song M, Zhao R, Liu X, Kang W, Lee J, et al. Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and in vivo. Front Cell Dev Biol. 2020;8:366 pubmed publisher
  • western blot; human; loading ...; fig 3d
Han B, Meng X, Wu P, Li Z, Li S, Zhang Y, et al. ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma. Theranostics. 2020;10:3351-3365 pubmed publisher
  • western blot; human; loading ...; fig 8
Thangaraj K, Balasubramanian B, Park S, Natesan K, Liu W, Manju V. Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells. Biomolecules. 2019;9: pubmed publisher
  • western blot; human; loading ...; fig 7e
Roy N, Monisha J, Padmavathi G, Lalhruaitluanga H, Kumar N, Singh A, et al. Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma. Biomolecules. 2019;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6b
Yue X, Zuo Y, Ke H, Luo J, Lou L, Qin W, et al. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. Biochem Pharmacol. 2017;137:29-50 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a
Sun J, Zhang X, Sun Y, Tang Z, Guo D. Effects of Hylomecon vernalis ethanol extracts on cell cycle and apoptosis of colon cancer cells. Mol Med Rep. 2017;15:3485-3492 pubmed publisher
  • western blot; human; loading ...; fig 3
Ji X, Pan C, Li X, Gao Y, Xia L, Quan X, et al. Trametes robiniophila may induce apoptosis and inhibit MMPs expression in the human gastric carcinoma cell line MKN-45. Oncol Lett. 2017;13:841-846 pubmed publisher
  • western blot; mouse; loading ...; fig 2b
Xiao F, Zhang J, Zhang C, An W. Hepatic stimulator substance inhibits calcium overflow through the mitochondria-associated membrane compartment during nonalcoholic steatohepatitis. Lab Invest. 2017;97:289-301 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7a
Zhu X, Wang K, Zhang K, Zhang T, Yin Y, Xu F. Ziyuglycoside I Inhibits the Proliferation of MDA-MB-231 Breast Carcinoma Cells through Inducing p53-Mediated G2/M Cell Cycle Arrest and Intrinsic/Extrinsic Apoptosis. Int J Mol Sci. 2016;17: pubmed
  • western blot; human; 1:500; fig 6
Zhan Y, Mou L, Cheng K, Wang C, Deng X, Chen J, et al. Hepatocellular carcinoma stem cell-like cells are enriched following low-dose 5-fluorouracil chemotherapy. Oncol Lett. 2016;12:2511-2516 pubmed
  • western blot; human; loading ...; fig 5b
Cheng S, Jiang X, Ding C, Du C, Owusu Ansah K, Weng X, et al. Expression and Critical Role of Interleukin Enhancer Binding Factor 2 in Hepatocellular Carcinoma. Int J Mol Sci. 2016;17: pubmed publisher
  • western blot; human; 1:1000; fig 2
Geng J, Li J, Huang T, Zhao K, Chen Q, Guo W, et al. A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria. Mol Med Rep. 2016;14:1970-8 pubmed publisher
  • western blot; human; 1:800; fig 4a
Zhou X, Wei Y, Qiu S, Xu Y, Zhang T, Zhang S. Propofol Decreases Endoplasmic Reticulum Stress-Mediated Apoptosis in Retinal Pigment Epithelial Cells. PLoS ONE. 2016;11:e0157590 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.