product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rpb1 NTD (D8L4Y) Rabbit mAb
catalog :
14958
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D8L4Y
reactivity :
human, mouse
application :
western blot, chromatin immunoprecipitation, ChIP-Seq
citations: 12
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; 1:50; fig s5
Gusyatiner O, Bady P, Pham M, Lei Y, Park J, Daniel R, et al. BET inhibitors repress expression of interferon-stimulated genes and synergize with HDAC inhibitors in glioblastoma. Neuro Oncol. 2021;23:1680-1692 pubmed publisher
  • western blot; human; loading ...; fig 1c
Tufegdzic Vidakovic A, Mitter R, Kelly G, Neumann M, Harreman M, Rodríguez Martínez M, et al. Regulation of the RNAPII Pool Is Integral to the DNA Damage Response. Cell. 2020;180:1245-1261.e21 pubmed publisher
  • chromatin immunoprecipitation; human; 1:147; loading ...; fig s27, s28
  • western blot; human; 1:1000; loading ...; fig s25a, s25b, s26
Ghezzi C, Wong A, Chen B, Ribalet B, Damoiseaux R, Clark P. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. Nat Commun. 2019;10:5444 pubmed publisher
  • chromatin immunoprecipitation; mouse; loading ...; fig e1j
Zhang H, Emerson D, Gilgenast T, Titus K, Lan Y, Huang P, et al. Chromatin structure dynamics during the mitosis-to-G1 phase transition. Nature. 2019;576:158-162 pubmed publisher
  • ChIP-Seq; mouse; loading ...; fig s6i
Turberfield A, Kondo T, Nakayama M, Koseki Y, King H, Koseki H, et al. KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity. Nucleic Acids Res. 2019;47:9005-9023 pubmed publisher
Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, et al. The role of Mediator and Little Elongation Complex in transcription termination. Nat Commun. 2020;11:1063 pubmed publisher
Blake D, Vaseva A, Hodge R, Kline M, Gilbert T, Tyagi V, et al. Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer. Sci Signal. 2019;12: pubmed publisher
Gregersen L, Mitter R, Ugalde A, Nojima T, Proudfoot N, Agami R, et al. SCAF4 and SCAF8, mRNA Anti-Terminator Proteins. Cell. 2019;: pubmed publisher
Sharma P, Lioutas A, Fernandez Fuentes N, Quilez J, Carbonell Caballero J, Wright R, et al. Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription. Mol Cell. 2019;73:84-96.e7 pubmed publisher
Bornelöv S, Reynolds N, Xenophontos M, Gharbi S, Johnstone E, Floyd R, et al. The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression. Mol Cell. 2018;71:56-72.e4 pubmed publisher
Cardiello J, Goodrich J, Kugel J. Heat Shock Causes a Reversible Increase in RNA Polymerase II Occupancy Downstream of mRNA Genes, Consistent with a Global Loss in Transcriptional Termination. Mol Cell Biol. 2018;38: pubmed publisher
Sze C, Cao K, Collings C, Marshall S, Rendleman E, Ozark P, et al. Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation. Genes Dev. 2017;31:1732-1737 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.